547 related articles for article (PubMed ID: 21471965)
1. Suppression of lung adenocarcinoma progression by Nkx2-1.
Winslow MM; Dayton TL; Verhaak RG; Kim-Kiselak C; Snyder EL; Feldser DM; Hubbard DD; DuPage MJ; Whittaker CA; Hoersch S; Yoon S; Crowley D; Bronson RT; Chiang DY; Meyerson M; Jacks T
Nature; 2011 May; 473(7345):101-4. PubMed ID: 21471965
[TBL] [Abstract][Full Text] [Related]
2. Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis.
Li CM; Gocheva V; Oudin MJ; Bhutkar A; Wang SY; Date SR; Ng SR; Whittaker CA; Bronson RT; Snyder EL; Gertler FB; Jacks T
Genes Dev; 2015 Sep; 29(17):1850-62. PubMed ID: 26341558
[TBL] [Abstract][Full Text] [Related]
3. NKX2-1-mediated p53 expression modulates lung adenocarcinoma progression via modulating IKKβ/NF-κB activation.
Chen PM; Wu TC; Cheng YW; Chen CY; Lee H
Oncotarget; 2015 Jun; 6(16):14274-89. PubMed ID: 25881545
[TBL] [Abstract][Full Text] [Related]
4. Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung.
Maeda Y; Tsuchiya T; Hao H; Tompkins DH; Xu Y; Mucenski ML; Du L; Keiser AR; Fukazawa T; Naomoto Y; Nagayasu T; Whitsett JA
J Clin Invest; 2012 Dec; 122(12):4388-400. PubMed ID: 23143308
[TBL] [Abstract][Full Text] [Related]
5. KRAS and NKX2-1 Mutations in Invasive Mucinous Adenocarcinoma of the Lung.
Hwang DH; Sholl LM; Rojas-Rudilla V; Hall DL; Shivdasani P; Garcia EP; MacConaill LE; Vivero M; Hornick JL; Kuo FC; Lindeman NI; Dong F
J Thorac Oncol; 2016 Apr; 11(4):496-503. PubMed ID: 26829311
[TBL] [Abstract][Full Text] [Related]
6. Inactivating mutations and hypermethylation of the NKX2-1/TTF-1 gene in non-terminal respiratory unit-type lung adenocarcinomas.
Matsubara D; Soda M; Yoshimoto T; Amano Y; Sakuma Y; Yamato A; Ueno T; Kojima S; Shibano T; Hosono Y; Kawazu M; Yamashita Y; Endo S; Hagiwara K; Fukayama M; Takahashi T; Mano H; Niki T
Cancer Sci; 2017 Sep; 108(9):1888-1896. PubMed ID: 28677170
[TBL] [Abstract][Full Text] [Related]
7. LKB1 loss by alteration of the NKX2-1/p53 pathway promotes tumor malignancy and predicts poor survival and relapse in lung adenocarcinomas.
Tsai LH; Chen PM; Cheng YW; Chen CY; Sheu GT; Wu TC; Lee H
Oncogene; 2014 Jul; 33(29):3851-60. PubMed ID: 23995788
[TBL] [Abstract][Full Text] [Related]
8. Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1).
Runkle EA; Rice SJ; Qi J; Masser D; Antonetti DA; Winslow MM; Mu D
J Biol Chem; 2012 Aug; 287(34):28790-801. PubMed ID: 22761434
[TBL] [Abstract][Full Text] [Related]
9. Obligate progression precedes lung adenocarcinoma dissemination.
Caswell DR; Chuang CH; Yang D; Chiou SH; Cheemalavagu S; Kim-Kiselak C; Connolly A; Winslow MM
Cancer Discov; 2014 Jul; 4(7):781-9. PubMed ID: 24740995
[TBL] [Abstract][Full Text] [Related]
10. Thyroid transcription factor-1-regulated microRNA-532-5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells.
Griesing S; Kajino T; Tai MC; Liu Z; Nakatochi M; Shimada Y; Suzuki M; Takahashi T
Cancer Sci; 2017 Jul; 108(7):1394-1404. PubMed ID: 28474808
[TBL] [Abstract][Full Text] [Related]
11. Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target.
Watanabe H; Francis JM; Woo MS; Etemad B; Lin W; Fries DF; Peng S; Snyder EL; Tata PR; Izzo F; Schinzel AC; Cho J; Hammerman PS; Verhaak RG; Hahn WC; Rajagopal J; Jacks T; Meyerson M
Genes Dev; 2013 Jan; 27(2):197-210. PubMed ID: 23322301
[TBL] [Abstract][Full Text] [Related]
12. The complexity of thyroid transcription factor 1 with both pro- and anti-oncogenic activities.
Mu D
J Biol Chem; 2013 Aug; 288(35):24992-25000. PubMed ID: 23818522
[TBL] [Abstract][Full Text] [Related]
13. Transcription factor and microRNA interactions in lung cells: an inhibitory link between NK2 homeobox 1, miR-200c and the developmental and oncogenic factors Nfib and Myb.
Tagne JB; Mohtar OR; Campbell JD; Lakshminarayanan M; Huang J; Hinds AC; Lu J; Ramirez MI
Respir Res; 2015 Feb; 16(1):22. PubMed ID: 25763778
[TBL] [Abstract][Full Text] [Related]
14. Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.
Snyder EL; Watanabe H; Magendantz M; Hoersch S; Chen TA; Wang DG; Crowley D; Whittaker CA; Meyerson M; Kimura S; Jacks T
Mol Cell; 2013 Apr; 50(2):185-99. PubMed ID: 23523371
[TBL] [Abstract][Full Text] [Related]
15. NKX2-1/TTF-1: an enigmatic oncogene that functions as a double-edged sword for cancer cell survival and progression.
Yamaguchi T; Hosono Y; Yanagisawa K; Takahashi T
Cancer Cell; 2013 Jun; 23(6):718-23. PubMed ID: 23763999
[TBL] [Abstract][Full Text] [Related]
16. MicroRNA-33a mediates the regulation of high mobility group AT-hook 2 gene (HMGA2) by thyroid transcription factor 1 (TTF-1/NKX2-1).
Rice SJ; Lai SC; Wood LW; Helsley KR; Runkle EA; Winslow MM; Mu D
J Biol Chem; 2013 Jun; 288(23):16348-16360. PubMed ID: 23625920
[TBL] [Abstract][Full Text] [Related]
17. Tumor Suppressor Activity of Selenbp1, a Direct Nkx2-1 Target, in Lung Adenocarcinoma.
Caswell DR; Chuang CH; Ma RK; Winters IP; Snyder EL; Winslow MM
Mol Cancer Res; 2018 Nov; 16(11):1737-1749. PubMed ID: 30002193
[TBL] [Abstract][Full Text] [Related]
18. Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors.
Tagne JB; Gupta S; Gower AC; Shen SS; Varma S; Lakshminarayanan M; Cao Y; Spira A; Volkert TL; Ramirez MI
PLoS One; 2012; 7(1):e29907. PubMed ID: 22242187
[TBL] [Abstract][Full Text] [Related]
19. Homeobox Transcription Factor NKX2-1 Promotes
Harada M; Sakai S; Ohhata T; Kitagawa K; Mikamo M; Nishimoto K; Uchida C; Niida H; Kotake Y; Sugimura H; Suda T; Kitagawa M
Mol Cancer Res; 2017 Oct; 15(10):1388-1397. PubMed ID: 28634225
[TBL] [Abstract][Full Text] [Related]
20. NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma.
Yamaguchi T; Yanagisawa K; Sugiyama R; Hosono Y; Shimada Y; Arima C; Kato S; Tomida S; Suzuki M; Osada H; Takahashi T
Cancer Cell; 2012 Mar; 21(3):348-61. PubMed ID: 22439932
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
