210 related articles for article (PubMed ID: 21472003)
1. Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways.
Gao N; Budhraja A; Cheng S; Liu EH; Chen J; Yang Z; Chen D; Zhang Z; Shi X
Cell Death Dis; 2011 Apr; 2(4):e140. PubMed ID: 21472003
[TBL] [Abstract][Full Text] [Related]
2. 3,3'-Diindolylmethane exhibits antileukemic activity in vitro and in vivo through a Akt-dependent process.
Gao N; Cheng S; Budhraja A; Liu EH; Chen J; Chen D; Yang Z; Luo J; Shi X; Zhang Z
PLoS One; 2012; 7(2):e31783. PubMed ID: 22363731
[TBL] [Abstract][Full Text] [Related]
3. Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity in vivo.
Budhraja A; Gao N; Zhang Z; Son YO; Cheng S; Wang X; Ding S; Hitron A; Chen G; Luo J; Shi X
Mol Cancer Ther; 2012 Jan; 11(1):132-42. PubMed ID: 22084167
[TBL] [Abstract][Full Text] [Related]
4. Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways.
Hahn M; Li W; Yu C; Rahmani M; Dent P; Grant S
Mol Cancer Ther; 2005 Mar; 4(3):457-70. PubMed ID: 15767555
[TBL] [Abstract][Full Text] [Related]
5. Farnesyltransferase inhibitors interact synergistically with the Chk1 inhibitor UCN-01 to induce apoptosis in human leukemia cells through interruption of both Akt and MEK/ERK pathways and activation of SEK1/JNK.
Dai Y; Rahmani M; Pei XY; Khanna P; Han SI; Mitchell C; Dent P; Grant S
Blood; 2005 Feb; 105(4):1706-16. PubMed ID: 15494423
[TBL] [Abstract][Full Text] [Related]
6. Ursolic acid induces apoptosis in human leukaemia cells and exhibits anti-leukaemic activity in nude mice through the PKB pathway.
Gao N; Cheng S; Budhraja A; Gao Z; Chen J; Liu EH; Huang C; Chen D; Yang Z; Liu Q; Li P; Shi X; Zhang Z
Br J Pharmacol; 2012 Mar; 165(6):1813-1826. PubMed ID: 21950524
[TBL] [Abstract][Full Text] [Related]
7. 2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process.
Gao N; Rahmani M; Dent P; Grant S
Oncogene; 2005 May; 24(23):3797-809. PubMed ID: 15782127
[TBL] [Abstract][Full Text] [Related]
8. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
Rahmani M; Aust MM; Attkisson E; Williams DC; Ferreira-Gonzalez A; Grant S
Cancer Res; 2013 Feb; 73(4):1340-51. PubMed ID: 23243017
[TBL] [Abstract][Full Text] [Related]
9. RhoA/ROCK/PTEN signaling is involved in AT-101-mediated apoptosis in human leukemia cells in vitro and in vivo.
Li G; Liu L; Shan C; Cheng Q; Budhraja A; Zhou T; Cui H; Gao N
Cell Death Dis; 2014 Jan; 5(1):e998. PubMed ID: 24434521
[TBL] [Abstract][Full Text] [Related]
10. Interruption of the MEK/ERK signaling cascade promotes dihydroartemisinin-induced apoptosis in vitro and in vivo.
Gao N; Budhraja A; Cheng S; Liu EH; Huang C; Chen J; Yang Z; Chen D; Zhang Z; Shi X
Apoptosis; 2011 May; 16(5):511-23. PubMed ID: 21336837
[TBL] [Abstract][Full Text] [Related]
11. Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK- and NF-kappaB-dependent process.
Dai Y; Rahmani M; Grant S
Oncogene; 2003 Oct; 22(46):7108-22. PubMed ID: 14562039
[TBL] [Abstract][Full Text] [Related]
12. The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib.
Yu C; Rahmani M; Dent P; Grant S
Exp Cell Res; 2004 May; 295(2):555-66. PubMed ID: 15093752
[TBL] [Abstract][Full Text] [Related]
13. Downregulation of Mcl-1 through inhibition of translation contributes to benzyl isothiocyanate-induced cell cycle arrest and apoptosis in human leukemia cells.
Zhou T; Li G; Cao B; Liu L; Cheng Q; Kong H; Shan C; Huang X; Chen J; Gao N
Cell Death Dis; 2013 Feb; 4(2):e515. PubMed ID: 23449451
[TBL] [Abstract][Full Text] [Related]
14. Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK- and AKT-dependent process.
Yu C; Rahmani M; Almenara J; Sausville EA; Dent P; Grant S
Oncogene; 2004 Feb; 23(7):1364-76. PubMed ID: 14647418
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of the PI3K pathway sensitizes fludarabine-induced apoptosis in human leukemic cells through an inactivation of MAPK-dependent pathway.
Yu C; Mao X; Li WX
Biochem Biophys Res Commun; 2005 Jun; 331(2):391-7. PubMed ID: 15850772
[TBL] [Abstract][Full Text] [Related]
16. Synergistic antileukemic interactions between 17-AAG and UCN-01 involve interruption of RAF/MEK- and AKT-related pathways.
Jia W; Yu C; Rahmani M; Krystal G; Sausville EA; Dent P; Grant S
Blood; 2003 Sep; 102(5):1824-32. PubMed ID: 12738674
[TBL] [Abstract][Full Text] [Related]
17. Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
Rahmani M; Reese E; Dai Y; Bauer C; Payne SG; Dent P; Spiegel S; Grant S
Cancer Res; 2005 Mar; 65(6):2422-32. PubMed ID: 15781658
[TBL] [Abstract][Full Text] [Related]
18. The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells.
Maggio SC; Rosato RR; Kramer LB; Dai Y; Rahmani M; Paik DS; Czarnik AC; Payne SG; Spiegel S; Grant S
Cancer Res; 2004 Apr; 64(7):2590-600. PubMed ID: 15059916
[TBL] [Abstract][Full Text] [Related]
19. The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
Yu C; Rahmani M; Dai Y; Conrad D; Krystal G; Dent P; Grant S
Cancer Res; 2003 Apr; 63(8):1822-33. PubMed ID: 12702569
[TBL] [Abstract][Full Text] [Related]
20. Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of Bax.
Cheng S; Gao N; Zhang Z; Chen G; Budhraja A; Ke Z; Son YO; Wang X; Luo J; Shi X
Clin Cancer Res; 2010 Dec; 16(23):5679-91. PubMed ID: 21138867
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]