These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 21473615)

  • 21. Multienzyme Kinetics and Sequential Metabolism.
    Wienkers LC; Rock BM
    Methods Mol Biol; 2021; 2342():89-112. PubMed ID: 34272692
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substates.
    Lampe JN; Brandman R; Sivaramakrishnan S; de Montellano PRO
    J Biol Chem; 2010 Mar; 285(13):9594-9603. PubMed ID: 20097757
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Folding funnels and conformational transitions via hinge-bending motions.
    Kumar S; Ma B; Tsai CJ; Wolfson H; Nussinov R
    Cell Biochem Biophys; 1999; 31(2):141-64. PubMed ID: 10593256
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Cytochrome P450 structure-function: insights from molecular dynamics simulations.
    Nair PC; McKinnon RA; Miners JO
    Drug Metab Rev; 2016 Aug; 48(3):434-52. PubMed ID: 27167388
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Functional promiscuity correlates with conformational heterogeneity in A-class glutathione S-transferases.
    Hou L; Honaker MT; Shireman LM; Balogh LM; Roberts AG; Ng KC; Nath A; Atkins WM
    J Biol Chem; 2007 Aug; 282(32):23264-74. PubMed ID: 17561509
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Conformational plasticity of an enzyme during catalysis: intricate coupling between cyclophilin A dynamics and substrate turnover.
    McGowan LC; Hamelberg D
    Biophys J; 2013 Jan; 104(1):216-26. PubMed ID: 23332074
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Enzyme promiscuity: mechanism and applications.
    Hult K; Berglund P
    Trends Biotechnol; 2007 May; 25(5):231-8. PubMed ID: 17379338
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Differential behavior of the sub-sites of cytochrome 450 active site in binding of substrates, and products (implications for coupling/uncoupling).
    Narasimhulu S
    Biochim Biophys Acta; 2007 Mar; 1770(3):360-75. PubMed ID: 17134838
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Allosteric P450 mechanisms: multiple binding sites, multiple conformers or both?
    Davydov DR; Halpert JR
    Expert Opin Drug Metab Toxicol; 2008 Dec; 4(12):1523-35. PubMed ID: 19040328
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A shifting specificity model for enzyme catalysis.
    Britt BM
    J Theor Biol; 1993 Sep; 164(2):181-90. PubMed ID: 8246515
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Odd Loop Regions of XenA and XenB Enzymes Modulate Their Interaction with Nitro-explosives Compounds and Provide Structural Support for Their Regioselectivity.
    Osorio MI; Cabrera MA; González-Nilo F; Pérez-Donoso JM
    J Chem Inf Model; 2019 Sep; 59(9):3860-3870. PubMed ID: 31454238
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Conformational analyses of the reaction coordinate of glycosidases.
    Davies GJ; Planas A; Rovira C
    Acc Chem Res; 2012 Feb; 45(2):308-16. PubMed ID: 21923088
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Dynamic disorder in simple enzymatic reactions induces stochastic amplification of substrate.
    Gupta A; Milias-Argeitis A; Khammash M
    J R Soc Interface; 2017 Jul; 14(132):. PubMed ID: 28747400
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Enzyme dynamics from NMR spectroscopy.
    Palmer AG
    Acc Chem Res; 2015 Feb; 48(2):457-65. PubMed ID: 25574774
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active-site residues.
    Hall KR; Robins KJ; Williams EM; Rich MH; Calcott MJ; Copp JN; Little RF; Schwörer R; Evans GB; Patrick WM; Ackerley DF
    Elife; 2020 Nov; 9():. PubMed ID: 33185191
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Promiscuity of Exiguobacterium sp. AT1b o-succinylbenzoate synthase illustrates evolutionary transitions in the OSBS family.
    Brizendine AM; Odokonyero D; McMillan AW; Zhu M; Hull K; Romo D; Glasner ME
    Biochem Biophys Res Commun; 2014 Jul; 450(1):679-84. PubMed ID: 24937446
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Reexamination of induced fit as a determinant of substrate specificity in enzymatic reactions.
    Post CB; Ray WJ
    Biochemistry; 1995 Dec; 34(49):15881-5. PubMed ID: 8519743
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Transition state analysis of the coupling of drug transport to ATP hydrolysis by P-glycoprotein.
    Al-Shawi MK; Polar MK; Omote H; Figler RA
    J Biol Chem; 2003 Dec; 278(52):52629-40. PubMed ID: 14551217
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Ligand-induced conformational heterogeneity of cytochrome P450 CYP119 identified by 2D NMR spectroscopy with the unnatural amino acid (13)C-p-methoxyphenylalanine.
    Lampe JN; Floor SN; Gross JD; Nishida CR; Jiang Y; Trnka MJ; Ortiz de Montellano PR
    J Am Chem Soc; 2008 Dec; 130(48):16168-9. PubMed ID: 18998650
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Conformational dynamics and enzyme evolution.
    Petrović D; Risso VA; Kamerlin SCL; Sanchez-Ruiz JM
    J R Soc Interface; 2018 Jul; 15(144):. PubMed ID: 30021929
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.