217 related articles for article (PubMed ID: 21475772)
1. A novel family of RGD-containing disintegrins (Tablysin-15) from the salivary gland of the horsefly Tabanus yao targets αIIbβ3 or αVβ3 and inhibits platelet aggregation and angiogenesis.
Ma D; Xu X; An S; Liu H; Yang X; Andersen JF; Wang Y; Tokumasu F; Ribeiro JM; Francischetti IM; Lai R
Thromb Haemost; 2011 Jun; 105(6):1032-45. PubMed ID: 21475772
[TBL] [Abstract][Full Text] [Related]
2. Modulation of RGD sequence motifs regulates disintegrin recognition of alphaIIb beta3 and alpha5 beta1 integrin complexes. Replacement of elegantin alanine-50 with proline, N-terminal to the RGD sequence, diminishes recognition of the alpha5 beta1 complex with restoration induced by Mn2+ cation.
Rahman S; Aitken A; Flynn G; Formstone C; Savidge GF
Biochem J; 1998 Oct; 335 ( Pt 2)(Pt 2):247-57. PubMed ID: 9761721
[TBL] [Abstract][Full Text] [Related]
3. Disintegrin Tablysin-15 Suppresses Cancer Hallmarks in Melanoma Cells by Blocking FAK/Akt/ERK and NF-κB Signaling.
Deng Z; Zeng Q; Chai J; Zhang B; Zheng W; Xu X; Wu J
Curr Cancer Drug Targets; 2020; 20(4):306-315. PubMed ID: 31893992
[TBL] [Abstract][Full Text] [Related]
4. Accutin, a new disintegrin, inhibits angiogenesis in vitro and in vivo by acting as integrin alphavbeta3 antagonist and inducing apoptosis.
Yeh CH; Peng HC; Huang TF
Blood; 1998 Nov; 92(9):3268-76. PubMed ID: 9787163
[TBL] [Abstract][Full Text] [Related]
5. The anticancer properties and mechanism of action of tablysin-15, the RGD-containing disintegrin, in breast cancer cells.
Deng Z; Chai J; Zeng Q; Zhang B; Ye T; Chen X; Xu X
Int J Biol Macromol; 2019 May; 129():1155-1167. PubMed ID: 30660566
[TBL] [Abstract][Full Text] [Related]
6. Disagregin is a fibrinogen receptor antagonist lacking the Arg-Gly-Asp sequence from the tick, Ornithodoros moubata.
Karczewski J; Endris R; Connolly TM
J Biol Chem; 1994 Mar; 269(9):6702-8. PubMed ID: 8120028
[TBL] [Abstract][Full Text] [Related]
7. Expression and characterization of a fibrinogenolytic enzyme from horsefly salivary gland.
Sheng X; Gao L; Lu X; Wang Y; Han Y; Meng P; Chen W; Lu Q
Protein Expr Purif; 2017 Jan; 129():135-142. PubMed ID: 27138045
[TBL] [Abstract][Full Text] [Related]
8. Characterization of Neuwiedin, a new disintegrin from Bothrops neuwiedi venom gland with distinct cysteine pattern.
Lima-Dos-Santos I; Della-Casa MS; Portes-Junior JA; Calabria PA; Magalhães GS; Moura-da-Silva AM
Toxicon; 2015 Sep; 104():57-64. PubMed ID: 26272708
[TBL] [Abstract][Full Text] [Related]
9. A horsefly saliva antigen 5-like protein containing RTS motif is an angiogenesis inhibitor.
Ma D; Gao L; An S; Song Y; Wu J; Xu X; Lai R
Toxicon; 2010 Jan; 55(1):45-51. PubMed ID: 19635491
[TBL] [Abstract][Full Text] [Related]
10. Effect of amino acids near the RGD sequence on binding activities between αIIbβ3 integrin and fibrinogen in the presence of RGD-containing synthetic peptides from elegantin and angustatin.
Oyama E; Takahashi H; Ishii K
Peptides; 2017 Oct; 96():31-37. PubMed ID: 28887046
[TBL] [Abstract][Full Text] [Related]
11. Disintegrins from hematophagous sources.
Assumpcao TC; Ribeiro JM; Francischetti IM
Toxins (Basel); 2012 May; 4(5):296-322. PubMed ID: 22778902
[TBL] [Abstract][Full Text] [Related]
12. Crystal structure of trimestatin, a disintegrin containing a cell adhesion recognition motif RGD.
Fujii Y; Okuda D; Fujimoto Z; Horii K; Morita T; Mizuno H
J Mol Biol; 2003 Oct; 332(5):1115-22. PubMed ID: 14499613
[TBL] [Abstract][Full Text] [Related]
13. Structure of protein having inhibitory disintegrin and leukotriene scavenging functions contained in single domain.
Xu X; Francischetti IM; Lai R; Ribeiro JM; Andersen JF
J Biol Chem; 2012 Mar; 287(14):10967-76. PubMed ID: 22311975
[TBL] [Abstract][Full Text] [Related]
14. Proteolytic cleavage of the beta1 subunit of platelet alpha2beta1 integrin by the metalloproteinase jararhagin compromises collagen-stimulated phosphorylation of pp72.
Kamiguti AS; Markland FS; Zhou Q; Laing GD; Theakston RD; Zuzel M
J Biol Chem; 1997 Dec; 272(51):32599-605. PubMed ID: 9405475
[TBL] [Abstract][Full Text] [Related]
15. rJararacin, a recombinant disintegrin from Bothrops jararaca venom: Exploring its effects on hemostasis and thrombosis.
David V; Wermelinger LS; Frattani FS; Lima AGF; Santos YFS; Mourão PAS; Almeida FCL; Kurtenbach E; Zingali RB
Arch Biochem Biophys; 2023 Apr; 738():109557. PubMed ID: 36878339
[TBL] [Abstract][Full Text] [Related]
16. A new short chain RGD-containing disintegrin, accutin, inhibits the common pathway of human platelet aggregation.
Yeh CH; Peng HC; Yih JB; Huang TF
Biochim Biophys Acta; 1998 Nov; 1425(3):493-504. PubMed ID: 9838213
[TBL] [Abstract][Full Text] [Related]
17. Aegyptin, a novel mosquito salivary gland protein, specifically binds to collagen and prevents its interaction with platelet glycoprotein VI, integrin alpha2beta1, and von Willebrand factor.
Calvo E; Tokumasu F; Marinotti O; Villeval JL; Ribeiro JMC; Francischetti IMB
J Biol Chem; 2007 Sep; 282(37):26928-26938. PubMed ID: 17650501
[TBL] [Abstract][Full Text] [Related]
18. Induction of fibrinogen binding and platelet aggregation as a potential intrinsic property of various glycoprotein IIb/IIIa (alphaIIbbeta3) inhibitors.
Peter K; Schwarz M; Ylänne J; Kohler B; Moser M; Nordt T; Salbach P; Kübler W; Bode C
Blood; 1998 Nov; 92(9):3240-9. PubMed ID: 9787160
[TBL] [Abstract][Full Text] [Related]
19. Savignygrin, a platelet aggregation inhibitor from the soft tick Ornithodoros savignyi, presents the RGD integrin recognition motif on the Kunitz-BPTI fold.
Mans BJ; Louw AI; Neitz AW
J Biol Chem; 2002 Jun; 277(24):21371-8. PubMed ID: 11932256
[TBL] [Abstract][Full Text] [Related]
20. Cloning, expression, and hemostatic activities of a disintegrin, r-mojastin 1, from the mohave rattlesnake (Crotalus scutulatus scutulatus).
Sánchez EE; Lucena SE; Reyes S; Soto JG; Cantu E; Lopez-Johnston JC; Guerrero B; Salazar AM; Rodríguez-Acosta A; Galán JA; Tao WA; Pérez JC
Thromb Res; 2010 Sep; 126(3):e211-9. PubMed ID: 20598348
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]