134 related articles for article (PubMed ID: 21476495)
21. Synergistic modulation of cystinyl aminopeptidase by divalent cation chelators.
Demaegdt H; Laeremans H; De Backer JP; Mosselmans S; Le MT; Kersemans V; Michotte Y; Vauquelin G; Vanderheyden PM
Biochem Pharmacol; 2004 Sep; 68(5):893-900. PubMed ID: 15294452
[TBL] [Abstract][Full Text] [Related]
22. Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening.
Engen K; Rosenström U; Axelsson H; Konda V; Dahllund L; Otrocka M; Sigmundsson K; Nikolaou A; Vauquelin G; Hallberg M; Jenmalm Jensen A; Lundbäck T; Larhed M
Assay Drug Dev Technol; 2016 Apr; 14(3):180-93. PubMed ID: 27078680
[TBL] [Abstract][Full Text] [Related]
23. Macrocyclic amino carboxylates as selective MMP-8 inhibitors.
Cherney RJ; Wang L; Meyer DT; Xue CB; Wasserman ZR; Hardman KD; Welch PK; Covington MB; Copeland RA; Arner EC; DeGrado WF; Decicco CP
J Med Chem; 1998 May; 41(11):1749-51. PubMed ID: 9599226
[No Abstract] [Full Text] [Related]
24. Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers.
Albiston AL; Diwakarla S; Fernando RN; Mountford SJ; Yeatman HR; Morgan B; Pham V; Holien JK; Parker MW; Thompson PE; Chai SY
Br J Pharmacol; 2011 Sep; 164(1):37-47. PubMed ID: 21470200
[TBL] [Abstract][Full Text] [Related]
25. Insulin-regulated aminopeptidase/placental leucil Aminopeptidase (IRAP/P-lAP) and angiotensin IV-forming activities are modified in serum of rats with breast cancer induced by N-methyl-nitrosourea.
Pilar Carrera M; Ramírez-Expósito MJ; Dueñas B; Dolores Mayas M; Jesús García M; De la Chica S; Cortés P; Ruíz-Sanjuan M; Martínez-Martos JM
Anticancer Res; 2006; 26(2A):1011-4. PubMed ID: 16619500
[TBL] [Abstract][Full Text] [Related]
26. The most potent organophosphorus inhibitors of leucine aminopeptidase. Structure-based design, chemistry, and activity.
Grembecka J; Mucha A; Cierpicki T; Kafarski P
J Med Chem; 2003 Jun; 46(13):2641-55. PubMed ID: 12801228
[TBL] [Abstract][Full Text] [Related]
27. Blockade of pro-cognitive effects of angiotensin IV and physostigmine in mice by oxytocin antagonism.
Gard PR; Naylor C; Ali S; Partington C
Eur J Pharmacol; 2012 May; 683(1-3):155-60. PubMed ID: 22433837
[TBL] [Abstract][Full Text] [Related]
28. Development of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase.
Chai SY; Yeatman HR; Parker MW; Ascher DB; Thompson PE; Mulvey HT; Albiston AL
BMC Neurosci; 2008 Dec; 9 Suppl 2(Suppl 2):S14. PubMed ID: 19090987
[TBL] [Abstract][Full Text] [Related]
29. Assessment of biological activity of novel peptide analogues of angiotensin IV.
Gard PR; Olivier G; Golding B; Bourner C; Dang T; Haliru H; Higgins E; Kimberley H; Loginova O; Madhavi S; Ryan D
J Pharm Pharmacol; 2011 Apr; 63(4):565-71. PubMed ID: 21401609
[TBL] [Abstract][Full Text] [Related]
30. Insulin-regulated aminopeptidase: analysis of peptide substrate and inhibitor binding to the catalytic domain.
Ye S; Chai SY; Lew RA; Albiston AL
Biol Chem; 2007 Apr; 388(4):399-403. PubMed ID: 17391061
[TBL] [Abstract][Full Text] [Related]
31. Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity.
Devadas B; Freeman SK; Zupec ME; Lu HF; Nagarajan SR; Kishore NS; Lodge JK; Kuneman DW; McWherter CA; Vinjamoori DV; Getman DP; Gordon JI; Sikorski JA
J Med Chem; 1997 Aug; 40(16):2609-25. PubMed ID: 9258368
[TBL] [Abstract][Full Text] [Related]
32. Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors.
Engen K; Vanga SR; Lundbäck T; Agalo F; Konda V; Jensen AJ; Åqvist J; Gutiérrez-de-Terán H; Hallberg M; Larhed M; Rosenström U
ChemistryOpen; 2020 Mar; 9(3):325-337. PubMed ID: 32154052
[TBL] [Abstract][Full Text] [Related]
33. The angiotensin IV/AT4 receptor.
Chai SY; Fernando R; Peck G; Ye SY; Mendelsohn FA; Jenkins TA; Albiston AL
Cell Mol Life Sci; 2004 Nov; 61(21):2728-37. PubMed ID: 15549174
[TBL] [Abstract][Full Text] [Related]
34. Targeting the insulin-regulated aminopeptidase/AT4 receptor for cognitive disorders.
Hallberg M
Drug News Perspect; 2009 Apr; 22(3):133-9. PubMed ID: 19440555
[TBL] [Abstract][Full Text] [Related]
35. From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase.
Hallberg M; Larhed M
Front Pharmacol; 2020; 11():590855. PubMed ID: 33178027
[TBL] [Abstract][Full Text] [Related]
36. Gene knockout of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory.
Albiston AL; Fernando RN; Yeatman HR; Burns P; Ng L; Daswani D; Diwakarla S; Pham V; Chai SY
Neurobiol Learn Mem; 2010 Jan; 93(1):19-30. PubMed ID: 19660563
[TBL] [Abstract][Full Text] [Related]
37. Macrocyclic inhibitors of the malarial aspartic proteases plasmepsin I, II, and IV.
Ersmark K; Nervall M; Gutiérrez-de-Terán H; Hamelink E; Janka LK; Clemente JC; Dunn BM; Gogoll A; Samuelsson B; Qvist J; Hallberg A
Bioorg Med Chem; 2006 Apr; 14(7):2197-208. PubMed ID: 16307884
[TBL] [Abstract][Full Text] [Related]
38. Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors.
Malamas MS; Erdei J; Gunawan I; Turner J; Hu Y; Wagner E; Fan K; Chopra R; Olland A; Bard J; Jacobsen S; Magolda RL; Pangalos M; Robichaud AJ
J Med Chem; 2010 Feb; 53(3):1146-58. PubMed ID: 19968289
[TBL] [Abstract][Full Text] [Related]
39. In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.
Costanzo MJ; Almond HR; Hecker LR; Schott MR; Yabut SC; Zhang HC; Andrade-Gordon P; Corcoran TW; Giardino EC; Kauffman JA; Lewis JM; de Garavilla L; Haertlein BJ; Maryanoff BE
J Med Chem; 2005 Mar; 48(6):1984-2008. PubMed ID: 15771442
[TBL] [Abstract][Full Text] [Related]
40. Brain and peripheral angiotensin II type 1 receptors mediate renal vasoconstrictor and blood pressure responses to angiotensin IV in the rat.
Yang R; Smolders I; De Bundel D; Fouyn R; Halberg M; Demaegdt H; Vanderheyden P; Dupont AG
J Hypertens; 2008 May; 26(5):998-1007. PubMed ID: 18398343
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
