These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 21476971)

  • 41. Stereoselective metabolism of ifosfamide by human P-450s 3A4 and 2B6. Favorable metabolic properties of R-enantiomer.
    Roy P; Tretyakov O; Wright J; Waxman DJ
    Drug Metab Dispos; 1999 Nov; 27(11):1309-18. PubMed ID: 10534317
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Identification of the human liver cytochrome P450 isoenzyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid.
    Zhou S; Paxton JW; Tingle MD; Kestell P
    Drug Metab Dispos; 2000 Dec; 28(12):1449-56. PubMed ID: 11095582
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Characterization of mixtures of recombinant human cytochrome p450s as a screening model for metabolic stability in drug discovery.
    Hagen N; Olsen AK; Andersen JV; Tjørnelund J; Hansen SH
    Xenobiotica; 2002 Sep; 32(9):749-59. PubMed ID: 12396272
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Intestinal and hepatic metabolic activity of five cytochrome P450 enzymes: impact on prediction of first-pass metabolism.
    Galetin A; Houston JB
    J Pharmacol Exp Ther; 2006 Sep; 318(3):1220-9. PubMed ID: 16763093
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Inhibition kinetics of monoclonal antibodies against cytochromes P450.
    Mei Q; Tang C; Lin Y; Rushmore TH; Shou M
    Drug Metab Dispos; 2002 Jun; 30(6):701-8. PubMed ID: 12019198
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Utility of intersystem extrapolation factors in early reaction phenotyping and the quantitative extrapolation of human liver microsomal intrinsic clearance using recombinant cytochromes P450.
    Chen Y; Liu L; Nguyen K; Fretland AJ
    Drug Metab Dispos; 2011 Mar; 39(3):373-82. PubMed ID: 21148079
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Quantitative structure-activity relationships (QSARs) within substrates of human cytochromes P450 involved in drug metabolism.
    Lewis DF; Modi S; Dickins M
    Drug Metabol Drug Interact; 2001; 18(3-4):221-42. PubMed ID: 11791886
    [TBL] [Abstract][Full Text] [Related]  

  • 48. The interactions of a selective protein kinase C beta inhibitor with the human cytochromes P450.
    Ring BJ; Gillespie JS; Binkley SN; Campanale KM; Wrighton SA
    Drug Metab Dispos; 2002 Sep; 30(9):957-61. PubMed ID: 12167559
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
    Marill J; Cresteil T; Lanotte M; Chabot GG
    Mol Pharmacol; 2000 Dec; 58(6):1341-8. PubMed ID: 11093772
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Interaction of irinotecan (CPT-11) and its active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38) with human cytochrome P450 enzymes.
    Hanioka N; Ozawa S; Jinno H; Tanaka-Kagawa T; Nishimura T; Ando M; Sawada Ji J
    Drug Metab Dispos; 2002 Apr; 30(4):391-6. PubMed ID: 11901092
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Trimethoprim and sulfamethoxazole are selective inhibitors of CYP2C8 and CYP2C9, respectively.
    Wen X; Wang JS; Backman JT; Laitila J; Neuvonen PJ
    Drug Metab Dispos; 2002 Jun; 30(6):631-5. PubMed ID: 12019187
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity.
    Krasulova K; Holas O; Anzenbacher P
    Molecules; 2017 Nov; 22(11):. PubMed ID: 29099769
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Enantioselective inhibition of Cytochrome P450-mediated drug metabolism by a novel antithrombotic agent, S002-333: Major effect on CYP2B6.
    Bhateria M; Ramakrishna R; Puttrevu SK; Saxena AK; Bhatta RS
    Chem Biol Interact; 2016 Aug; 256():257-65. PubMed ID: 27387538
    [TBL] [Abstract][Full Text] [Related]  

  • 54. In-vitro metabolism of glycyrrhetinic acid by human and rat liver microsomes and its interactions with six CYP substrates.
    Zhao K; Ding M; Cao H; Cao ZX
    J Pharm Pharmacol; 2012 Oct; 64(10):1445-51. PubMed ID: 22943175
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of ethosuximide by human hepatic microsomal enzymes.
    Bachmann K; He Y; Sarver JG; Peng N
    Xenobiotica; 2003 Mar; 33(3):265-76. PubMed ID: 12637244
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Further assessment of 17alpha-ethinyl estradiol as an inhibitor of different human cytochrome P450 forms in vitro.
    Chang SY; Chen C; Yang Z; Rodrigues AD
    Drug Metab Dispos; 2009 Aug; 37(8):1667-75. PubMed ID: 19454483
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Role of CYP3A4 and CYP2C19 in the stereoselective metabolism of lansoprazole by human liver microsomes.
    Katsuki H; Hamada A; Nakamura C; Arimori K; Nakano M
    Eur J Clin Pharmacol; 2001 Dec; 57(10):709-15. PubMed ID: 11829200
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Inhibitory effects of amiodarone and its N-deethylated metabolite on human cytochrome P450 activities: prediction of in vivo drug interactions.
    Ohyama K; Nakajima M; Suzuki M; Shimada N; Yamazaki H; Yokoi T
    Br J Clin Pharmacol; 2000 Mar; 49(3):244-53. PubMed ID: 10718780
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil.
    Tracy TS; Korzekwa KR; Gonzalez FJ; Wainer IW
    Br J Clin Pharmacol; 1999 May; 47(5):545-52. PubMed ID: 10336579
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Reaction Phenotyping of Low-Turnover Compounds in Long-Term Hepatocyte Cultures Through Persistent Selective Inhibition of Cytochromes P450.
    Smith S; Lyman M; Ma B; Tweedie D; Menzel K
    Drug Metab Dispos; 2021 Nov; 49(11):995-1002. PubMed ID: 34407991
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.