BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 21477091)

  • 1. Comparative QSAR analyses of competitive CYP2C9 inhibitors using three-dimensional molecular descriptors.
    Lather V; Fernandes MX
    Chem Biol Drug Des; 2011 Jul; 78(1):112-23. PubMed ID: 21477091
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conformer- and alignment-independent model for predicting structurally diverse competitive CYP2C9 inhibitors.
    Afzelius L; Zamora I; Masimirembwa CM; Karlén A; Andersson TB; Mecucci S; Baroni M; Cruciani G
    J Med Chem; 2004 Feb; 47(4):907-14. PubMed ID: 14761192
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Three- and four-dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2C9 inhibitors.
    Ekins S; Bravi G; Binkley S; Gillespie JS; Ring BJ; Wikel JH; Wrighton SA
    Drug Metab Dispos; 2000 Aug; 28(8):994-1002. PubMed ID: 10901712
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative QSAR studies of CYP1A2 inhibitor flavonoids using 2D and 3D descriptors.
    Roy K; Roy PP
    Chem Biol Drug Des; 2008 Nov; 72(5):370-82. PubMed ID: 19012573
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 3D QSAR studies on protein tyrosine phosphatase 1B inhibitors: comparison of the quality and predictivity among 3D QSAR models obtained from different conformer-based alignments.
    Pandey G; Saxena AK
    J Chem Inf Model; 2006; 46(6):2579-90. PubMed ID: 17125198
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Three and four dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2D6 inhibitors.
    Ekins S; Bravi G; Binkley S; Gillespie JS; Ring BJ; Wikel JH; Wrighton SA
    Pharmacogenetics; 1999 Aug; 9(4):477-89. PubMed ID: 10780267
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modeling the activity of furin inhibitors using artificial neural network.
    Worachartcheewan A; Nantasenamat C; Naenna T; Isarankura-Na-Ayudhya C; Prachayasittikul V
    Eur J Med Chem; 2009 Apr; 44(4):1664-73. PubMed ID: 18977558
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel inhibitors of human histone deacetylase (HDAC) identified by QSAR modeling of known inhibitors, virtual screening, and experimental validation.
    Tang H; Wang XS; Huang XP; Roth BL; Butler KV; Kozikowski AP; Jung M; Tropsha A
    J Chem Inf Model; 2009 Feb; 49(2):461-76. PubMed ID: 19182860
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Predictive QSAR modeling of HIV reverse transcriptase inhibitor TIBO derivatives.
    Mandal AS; Roy K
    Eur J Med Chem; 2009 Apr; 44(4):1509-24. PubMed ID: 18760864
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.
    Schormann N; Senkovich O; Walker K; Wright DL; Anderson AC; Rosowsky A; Ananthan S; Shinkre B; Velu S; Chattopadhyay D
    Proteins; 2008 Dec; 73(4):889-901. PubMed ID: 18536013
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 4D-fingerprints, universal QSAR and QSPR descriptors.
    Senese CL; Duca J; Pan D; Hopfinger AJ; Tseng YJ
    J Chem Inf Comput Sci; 2004; 44(5):1526-39. PubMed ID: 15446810
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exploring QSAR and QAAR for inhibitors of cytochrome P450 2A6 and 2A5 enzymes using GFA and G/PLS techniques.
    Roy K; Roy PP
    Eur J Med Chem; 2009 May; 44(5):1941-51. PubMed ID: 19110342
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 3D QSAR studies of AChE inhibitors based on molecular docking scores and CoMFA.
    Akula N; Lecanu L; Greeson J; Papadopoulos V
    Bioorg Med Chem Lett; 2006 Dec; 16(24):6277-80. PubMed ID: 17049234
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Optimizing QSAR models for predicting ligand binding to the drug-metabolizing cytochrome P450 isoenzyme CYP2D6.
    Saraceno M; Massarelli I; Imbriani M; James TL; Bianucci AM
    Chem Biol Drug Des; 2011 Aug; 78(2):236-51. PubMed ID: 21575140
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein-based alignment in 3D-QSAR of FBPase inhibitors.
    Yi P; Di YT; Liu W; Hao XJ; Ming Y; Huang DS; Yang J; Yi ZZ; Li ZJ; Yang RD; Zhang JC
    Eur J Med Chem; 2011 Mar; 46(3):885-92. PubMed ID: 21269737
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Receptor-based 3D-QSAR studies of checkpoint Wee1 kinase inhibitors.
    Wichapong K; Lindner M; Pianwanit S; Kokpol S; Sippl W
    Eur J Med Chem; 2009 Apr; 44(4):1383-95. PubMed ID: 18976834
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exploring molecular shape analysis of styrylquinoline derivatives as HIV-1 integrase inhibitors.
    Leonard JT; Roy K
    Eur J Med Chem; 2008 Jan; 43(1):81-92. PubMed ID: 17452064
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Determination and prediction of xenoestrogens by recombinant yeast-based assay and QSAR.
    Li F; Chen J; Wang Z; Li J; Qiao X
    Chemosphere; 2009 Mar; 74(9):1152-7. PubMed ID: 19136139
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Competitive CYP2C9 inhibitors: enzyme inhibition studies, protein homology modeling, and three-dimensional quantitative structure-activity relationship analysis.
    Afzelius L; Zamora I; Ridderström M; Andersson TB; Karlén A; Masimirembwa CM
    Mol Pharmacol; 2001 Apr; 59(4):909-19. PubMed ID: 11259637
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular modeling studies of pyridopurinone derivatives--potential phosphodiesterase 5 inhibitors.
    Srivani P; Srinivas E; Raghu R; Sastry GN
    J Mol Graph Model; 2007 Jul; 26(1):378-90. PubMed ID: 17307372
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.