These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 21478863)

  • 1. ERK and PDE4 cooperate to induce RAF isoform switching in melanoma.
    Marquette A; André J; Bagot M; Bensussan A; Dumaz N
    Nat Struct Mol Biol; 2011 May; 18(5):584-91. PubMed ID: 21478863
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling.
    Dumaz N; Hayward R; Martin J; Ogilvie L; Hedley D; Curtin JA; Bastian BC; Springer C; Marais R
    Cancer Res; 2006 Oct; 66(19):9483-91. PubMed ID: 17018604
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism of RAF isoform switching induced by oncogenic RAS in melanoma.
    Dumaz N
    Small GTPases; 2011 Sep; 2(5):289-292. PubMed ID: 22292133
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PDE4D promotes FAK-mediated cell invasion in BRAF-mutated melanoma.
    Delyon J; Servy A; Laugier F; André J; Ortonne N; Battistella M; Mourah S; Bensussan A; Lebbé C; Dumaz N
    Oncogene; 2017 Jun; 36(23):3252-3262. PubMed ID: 28092671
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF.
    Poulikakos PI; Zhang C; Bollag G; Shokat KM; Rosen N
    Nature; 2010 Mar; 464(7287):427-30. PubMed ID: 20179705
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation.
    Li Y; Takahashi M; Stork PJS
    J Biol Chem; 2013 Sep; 288(38):27646-27657. PubMed ID: 23893412
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.
    Hatzivassiliou G; Song K; Yen I; Brandhuber BJ; Anderson DJ; Alvarado R; Ludlam MJ; Stokoe D; Gloor SL; Vigers G; Morales T; Aliagas I; Liu B; Sideris S; Hoeflich KP; Jaiswal BS; Seshagiri S; Koeppen H; Belvin M; Friedman LS; Malek S
    Nature; 2010 Mar; 464(7287):431-5. PubMed ID: 20130576
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The BRAF(V600E) inhibitor, PLX4032, increases type I collagen synthesis in melanoma cells.
    Jenkins MH; Croteau W; Mullins DW; Brinckerhoff CE
    Matrix Biol; 2015 Oct; 48():66-77. PubMed ID: 25989506
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth.
    Romeo Y; Moreau J; Zindy PJ; Saba-El-Leil M; Lavoie G; Dandachi F; Baptissart M; Borden KLB; Meloche S; Roux PP
    Oncogene; 2013 Jun; 32(24):2917-2926. PubMed ID: 22797077
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation.
    Wellbrock C; Marais R
    J Cell Biol; 2005 Aug; 170(5):703-8. PubMed ID: 16129781
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes.
    Buscà R; Abbe P; Mantoux F; Aberdam E; Peyssonnaux C; Eychène A; Ortonne JP; Ballotti R
    EMBO J; 2000 Jun; 19(12):2900-10. PubMed ID: 10856235
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ROS production induced by BRAF inhibitor treatment rewires metabolic processes affecting cell growth of melanoma cells.
    Cesi G; Walbrecq G; Zimmer A; Kreis S; Haan C
    Mol Cancer; 2017 Jun; 16(1):102. PubMed ID: 28595656
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cyclic AMP differentially regulates cell proliferation of normal human keratinocytes through ERK activation depending on the expression pattern of B-Raf.
    Takahashi H; Honma M; Miyauchi Y; Nakamura S; Ishida-Yamamoto A; Iizuka H
    Arch Dermatol Res; 2004 Jul; 296(2):74-82. PubMed ID: 15278365
    [TBL] [Abstract][Full Text] [Related]  

  • 14. c-Kit mutants require hypoxia-inducible factor 1alpha to transform melanocytes.
    Monsel G; Ortonne N; Bagot M; Bensussan A; Dumaz N
    Oncogene; 2010 Jan; 29(2):227-36. PubMed ID: 19802003
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vertical Inhibition of the RAF-MEK-ERK Cascade Induces Myogenic Differentiation, Apoptosis, and Tumor Regression in
    Garcia N; Del Pozo V; Yohe ME; Goodwin CM; Shackleford TJ; Wang L; Baxi K; Chen Y; Rogojina AT; Zimmerman SM; Peer CJ; Figg WD; Ignatius MS; Wood KC; Houghton PJ; Vaseva AV
    Mol Cancer Ther; 2022 Jan; 21(1):170-183. PubMed ID: 34737198
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RKTG sequesters B-Raf to the Golgi apparatus and inhibits the proliferation and tumorigenicity of human malignant melanoma cells.
    Fan F; Feng L; He J; Wang X; Jiang X; Zhang Y; Wang Z; Chen Y
    Carcinogenesis; 2008 Jun; 29(6):1157-63. PubMed ID: 18515281
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation.
    Nazarian R; Shi H; Wang Q; Kong X; Koya RC; Lee H; Chen Z; Lee MK; Attar N; Sazegar H; Chodon T; Nelson SF; McArthur G; Sosman JA; Ribas A; Lo RS
    Nature; 2010 Dec; 468(7326):973-7. PubMed ID: 21107323
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E).
    Poulikakos PI; Persaud Y; Janakiraman M; Kong X; Ng C; Moriceau G; Shi H; Atefi M; Titz B; Gabay MT; Salton M; Dahlman KB; Tadi M; Wargo JA; Flaherty KT; Kelley MC; Misteli T; Chapman PB; Sosman JA; Graeber TG; Ribas A; Lo RS; Rosen N; Solit DB
    Nature; 2011 Nov; 480(7377):387-90. PubMed ID: 22113612
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein Kinase CK2α Maintains Extracellular Signal-regulated Kinase (ERK) Activity in a CK2α Kinase-independent Manner to Promote Resistance to Inhibitors of RAF and MEK but Not ERK in BRAF Mutant Melanoma.
    Zhou B; Ritt DA; Morrison DK; Der CJ; Cox AD
    J Biol Chem; 2016 Aug; 291(34):17804-15. PubMed ID: 27226552
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional status and relationships of melanocortin 1 receptor signaling to the cAMP and extracellular signal-regulated protein kinases 1 and 2 pathways in human melanoma cells.
    Herraiz C; Journé F; Ghanem G; Jiménez-Cervantes C; García-Borrón JC
    Int J Biochem Cell Biol; 2012 Dec; 44(12):2244-52. PubMed ID: 23000456
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.