BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 21483943)

  • 1. Cyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analogues.
    Brumshtein B; Aguilar-Moncayo M; Benito JM; García Fernandez JM; Silman I; Shaaltiel Y; Aviezer D; Sussman JL; Futerman AH; Ortiz Mellet C
    Org Biomol Chem; 2011 Jun; 9(11):4160-7. PubMed ID: 21483943
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chaperone activity of bicyclic nojirimycin analogues for Gaucher mutations in comparison with N-(n-nonyl)deoxynojirimycin.
    Luan Z; Higaki K; Aguilar-Moncayo M; Ninomiya H; Ohno K; García-Moreno MI; Ortiz Mellet C; García Fernández JM; Suzuki Y
    Chembiochem; 2009 Nov; 10(17):2780-92. PubMed ID: 19830760
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Fluorescent sp2-iminosugar with pharmacological chaperone activity for gaucher disease: synthesis and intracellular distribution studies.
    Luan Z; Higaki K; Aguilar-Moncayo M; Li L; Ninomiya H; Nanba E; Ohno K; García-Moreno MI; Ortiz Mellet C; García Fernández JM; Suzuki Y
    Chembiochem; 2010 Nov; 11(17):2453-64. PubMed ID: 21064079
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidase.
    Aguilar-Moncayo M; García-Moreno MI; Trapero A; Egido-Gabás M; Llebaria A; Fernández JM; Mellet CO
    Org Biomol Chem; 2011 May; 9(10):3698-713. PubMed ID: 21451818
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 6-Amino-6-deoxy-5,6-di-N-(N'-octyliminomethylidene)nojirimycin: synthesis, biological evaluation, and crystal structure in complex with acid beta-glucosidase.
    Brumshtein B; Aguilar-Moncayo M; García-Moreno MI; Ortiz Mellet C; García Fernández JM; Silman I; Shaaltiel Y; Aviezer D; Sussman JL; Futerman AH
    Chembiochem; 2009 Jun; 10(9):1480-5. PubMed ID: 19437524
    [No Abstract]   [Full Text] [Related]  

  • 6. Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid beta-glucosidase: insights into the mechanism of chemical chaperone action in Gaucher disease.
    Brumshtein B; Greenblatt HM; Butters TD; Shaaltiel Y; Aviezer D; Silman I; Futerman AH; Sussman JL
    J Biol Chem; 2007 Sep; 282(39):29052-29058. PubMed ID: 17666401
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bicyclic isoureas derived from 1-deoxynojirimycin are potent inhibitors of β-glucocerebrosidase.
    Sevšek A; Čelan M; Erjavec B; Quarles van Ufford L; Sastre Toraño J; Moret EE; Pieters RJ; Martin NI
    Org Biomol Chem; 2016 Oct; 14(37):8670-3. PubMed ID: 27604065
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular structures of the inclusion complexes beta-cyclodextrin-1,2-bis(4-aminophenyl)ethane and beta-cyclodextrin-4,4'-diaminobiphenyl; packing of dimeric beta-cyclodextrin inclusion complexes.
    Giastas P; Yannakopoulou K; Mavridis IM
    Acta Crystallogr B; 2003 Apr; 59(Pt 2):287-99. PubMed ID: 12657820
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fluorescent-tagged sp2-iminosugars with potent β-glucosidase inhibitory activity.
    Aguilar-Moncayo M; García-Moreno MI; Stütz AE; García Fernández JM; Wrodnigg TM; Ortiz Mellet C
    Bioorg Med Chem; 2010 Nov; 18(21):7439-45. PubMed ID: 20889348
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of the inclusion complex of the antibacterial agent triclosan with cyclomaltoheptaose and NMR study of its molecular encapsulation in positively and negatively charged cyclomaltoheptaose derivatives.
    Paulidou A; Maffeo D; Yannakopoulou K; Mavridis IM
    Carbohydr Res; 2008 Oct; 343(15):2634-40. PubMed ID: 18684438
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective action of the iminosugar isofagomine, a pharmacological chaperone for mutant forms of acid-beta-glucosidase.
    Steet R; Chung S; Lee WS; Pine CW; Do H; Kornfeld S
    Biochem Pharmacol; 2007 May; 73(9):1376-83. PubMed ID: 17217920
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amphiphilic 1-deoxynojirimycin derivatives through click strategies for chemical chaperoning in N370S Gaucher cells.
    Diot JD; Garcia Moreno I; Twigg G; Ortiz Mellet C; Haupt K; Butters TD; Kovensky J; Gouin SG
    J Org Chem; 2011 Oct; 76(19):7757-68. PubMed ID: 21830816
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Miglustat (NB-DNJ) works as a chaperone for mutated acid beta-glucosidase in cells transfected with several Gaucher disease mutations.
    Alfonso P; Pampín S; Estrada J; Rodríguez-Rey JC; Giraldo P; Sancho J; Pocoví M
    Blood Cells Mol Dis; 2005; 35(2):268-76. PubMed ID: 16039881
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A 1H NMR Study of Host/Guest Supramolecular Complexes of a Curcumin Analogue with β-Cyclodextrin and a β-Cyclodextrin-Conjugated Gemini Surfactant.
    Poorghorban M; Karoyo AH; Grochulski P; Verrall RE; Wilson LD; Badea I
    Mol Pharm; 2015 Aug; 12(8):2993-3006. PubMed ID: 26083126
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase.
    Abian O; Alfonso P; Velazquez-Campoy A; Giraldo P; Pocovi M; Sancho J
    Mol Pharm; 2011 Dec; 8(6):2390-7. PubMed ID: 21988669
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Physicochemical and biological properties of 6(1),6(3),6(5)-tri-O-alpha-maltosyl-cyclomaltoheptaose (6(1),6(3),6(5)-tri-O-alpha-maltosyl-beta-cyclodextrin).
    Okada Y; Semma M; Ichikawa A
    Carbohydr Res; 2007 Jul; 342(10):1315-22. PubMed ID: 17498674
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The dimeric complex of cyclomaltoheptaose with 1,14-tetradecanedioic acid. Comparison with related complexes.
    Makedonopoulou S; Mavridis IM
    Carbohydr Res; 2001 Oct; 335(3):213-20. PubMed ID: 11578637
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acid beta-glucosidase: insights from structural analysis and relevance to Gaucher disease therapy.
    Kacher Y; Brumshtein B; Boldin-Adamsky S; Toker L; Shainskaya A; Silman I; Sussman JL; Futerman AH
    Biol Chem; 2008 Nov; 389(11):1361-9. PubMed ID: 18783340
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of cyclomaltoheptaose (beta-cyclodextrin) complexes with p-aminobenzoic acid and o-aminobenzoic acid.
    Zhang Y; Yu S; Bao F
    Carbohydr Res; 2008 Sep; 343(14):2504-8. PubMed ID: 18675404
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Induced circular dichroism and structural assignment of the cyclodextrin inclusion complexes of bicyclic azoalkanes.
    Bakirci H; Zhang X; Nau WM
    J Org Chem; 2005 Jan; 70(1):39-46. PubMed ID: 15624904
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.