These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 21486005)

  • 1. Gambogic acid, a natural product inhibitor of Hsp90.
    Davenport J; Manjarrez JR; Peterson L; Krumm B; Blagg BS; Matts RL
    J Nat Prod; 2011 May; 74(5):1085-92. PubMed ID: 21486005
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells.
    Zhang T; Hamza A; Cao X; Wang B; Yu S; Zhan CG; Sun D
    Mol Cancer Ther; 2008 Jan; 7(1):162-70. PubMed ID: 18202019
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novobiocin induces a distinct conformation of Hsp90 and alters Hsp90-cochaperone-client interactions.
    Yun BG; Huang W; Leach N; Hartson SD; Matts RL
    Biochemistry; 2004 Jun; 43(25):8217-29. PubMed ID: 15209518
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hsp90 regulates p50(cdc37) function during the biogenesis of the activeconformation of the heme-regulated eIF2 alpha kinase.
    Shao J; Grammatikakis N; Scroggins BT; Uma S; Huang W; Chen JJ; Hartson SD; Matts RL
    J Biol Chem; 2001 Jan; 276(1):206-14. PubMed ID: 11036079
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of celastrol to inhibit hsp90 and cdc37 interaction.
    Zhang T; Li Y; Yu Y; Zou P; Jiang Y; Sun D
    J Biol Chem; 2009 Dec; 284(51):35381-9. PubMed ID: 19858214
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein quality control of DYRK family protein kinases by the Hsp90-Cdc37 molecular chaperone.
    Miyata Y; Nishida E
    Biochim Biophys Acta Mol Cell Res; 2021 Sep; 1868(10):119081. PubMed ID: 34147560
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evidence that protein phosphatase 5 functions to negatively modulate the maturation of the Hsp90-dependent heme-regulated eIF2alpha kinase.
    Shao J; Hartson SD; Matts RL
    Biochemistry; 2002 May; 41(21):6770-9. PubMed ID: 12022881
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery.
    Hall JA; Seedarala S; Rice N; Kopel L; Halaweish F; Blagg BS
    J Nat Prod; 2015 Apr; 78(4):873-9. PubMed ID: 25756299
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors.
    Zhang MQ; Gaisser S; Nur-E-Alam M; Sheehan LS; Vousden WA; Gaitatzis N; Peck G; Coates NJ; Moss SJ; Radzom M; Foster TA; Sheridan RM; Gregory MA; Roe SM; Prodromou C; Pearl L; Boyd SM; Wilkinson B; Martin CJ
    J Med Chem; 2008 Sep; 51(18):5494-7. PubMed ID: 18800759
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90.
    Lundgren K; Zhang H; Brekken J; Huser N; Powell RE; Timple N; Busch DJ; Neely L; Sensintaffar JL; Yang YC; McKenzie A; Friedman J; Scannevin R; Kamal A; Hong K; Kasibhatla SR; Boehm MF; Burrows FJ
    Mol Cancer Ther; 2009 Apr; 8(4):921-9. PubMed ID: 19372565
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heat shock protein 90 inhibitors suppress aryl hydrocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and DNA adduct formation.
    Hughes D; Guttenplan JB; Marcus CB; Subbaramaiah K; Dannenberg AJ
    Cancer Prev Res (Phila); 2008 Nov; 1(6):485-93. PubMed ID: 19138996
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model.
    Gorska-Ponikowska M; Kuban-Jankowska A; Marino Gammazza A; Daca A; Wierzbicka JM; Zmijewski MA; Luu HH; Wozniak M; Cappello F
    Int J Mol Sci; 2020 Jan; 21(2):. PubMed ID: 31963524
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functioning of the Hsp90 machine in chaperoning checkpoint kinase I (Chk1) and the progesterone receptor (PR).
    Felts SJ; Karnitz LM; Toft DO
    Cell Stress Chaperones; 2007; 12(4):353-63. PubMed ID: 18229454
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specific association of a set of molecular chaperones including HSP90 and Cdc37 with MOK, a member of the mitogen-activated protein kinase superfamily.
    Miyata Y; Ikawa Y; Shibuya M; Nishida E
    J Biol Chem; 2001 Jun; 276(24):21841-8. PubMed ID: 11278794
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Convergent synthesis and discovery of a natural product-inspired paralog-selective Hsp90 inhibitor.
    Jeso V; Cherry L; Macklin TK; Pan SC; LoGrasso PV; Micalizio GC
    Org Lett; 2011 Oct; 13(19):5108-11. PubMed ID: 21866939
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hsp90 inhibitor geldanamycin attenuates the cytotoxicity of sunitinib in cardiomyocytes via inhibition of the autophagy pathway.
    Kimura T; Uesugi M; Takase K; Miyamoto N; Sawada K
    Toxicol Appl Pharmacol; 2017 Aug; 329():282-292. PubMed ID: 28624441
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, and structure--activity relationships for chimeric inhibitors of Hsp90.
    Shen G; Wang M; Welch TR; Blagg BS
    J Org Chem; 2006 Sep; 71(20):7618-31. PubMed ID: 16995666
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte.
    Ota A; Zhang J; Ping P; Han J; Wang Y
    Circ Res; 2010 Apr; 106(8):1404-12. PubMed ID: 20299663
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Molecular chaperone HSP90 as a novel target for cancer chemotherapy].
    Miyata Y
    Nihon Yakurigaku Zasshi; 2003 Jan; 121(1):33-42. PubMed ID: 12617036
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors.
    Smith JR; Clarke PA; de Billy E; Workman P
    Oncogene; 2009 Jan; 28(2):157-69. PubMed ID: 18931700
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.