These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 21486193)

  • 1. Surgical and pharmacological animal models used in drug metabolism and pharmacokinetics.
    Landskroner KA; Hess P; Treiber A
    Xenobiotica; 2011 Aug; 41(8):687-700. PubMed ID: 21486193
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Altered disposition of drugs in acute renal failure rat models: drug development strategies and perspectives.
    Srinivas NR
    Arzneimittelforschung; 2010; 60(12):731-48. PubMed ID: 21265465
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Use of radioactive compounds and autoradiography to determine drug tissue distribution.
    Solon EG
    Chem Res Toxicol; 2012 Mar; 25(3):543-55. PubMed ID: 22280496
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Drug transporter and cytochrome P450 mRNA expression in human ocular barriers: implications for ocular drug disposition.
    Zhang T; Xiang CD; Gale D; Carreiro S; Wu EY; Zhang EY
    Drug Metab Dispos; 2008 Jul; 36(7):1300-7. PubMed ID: 18411399
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Use of radiolabeled compounds in drug metabolism and pharmacokinetic studies.
    Isin EM; Elmore CS; Nilsson GN; Thompson RA; Weidolf L
    Chem Res Toxicol; 2012 Mar; 25(3):532-42. PubMed ID: 22372867
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In silico predictive metabolism: a structural/electronic filter method.
    Harris DL
    Curr Opin Drug Discov Devel; 2004 Jan; 7(1):43-8. PubMed ID: 14982147
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Addressing central nervous system (CNS) penetration in drug discovery: basics and implications of the evolving new concept.
    Reichel A
    Chem Biodivers; 2009 Nov; 6(11):2030-49. PubMed ID: 19937839
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A critical analysis of the interplay between cytochrome P450 3A and P-glycoprotein: recent insights from knockout and transgenic mice.
    van Waterschoot RA; Schinkel AH
    Pharmacol Rev; 2011 Jun; 63(2):390-410. PubMed ID: 21490128
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development and application of physiologically based pharmacokinetic-modeling tools to support drug discovery.
    Lüpfert C; Reichel A
    Chem Biodivers; 2005 Nov; 2(11):1462-86. PubMed ID: 17191947
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cunninghamella--a microbial model for drug metabolism studies--a review.
    Asha S; Vidyavathi M
    Biotechnol Adv; 2009; 27(1):16-29. PubMed ID: 18775773
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Building predictive ADMET models for early decisions in drug discovery.
    Penzotti JE; Landrum GA; Putta S
    Curr Opin Drug Discov Devel; 2004 Jan; 7(1):49-61. PubMed ID: 14982148
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Preclinical pharmacokinetics of a novel HIV-1 attachment inhibitor BMS-378806 and prediction of its human pharmacokinetics.
    Yang Z; Zadjura L; D'Arienzo C; Marino A; Santone K; Klunk L; Greene D; Lin PF; Colonno R; Wang T; Meanwell N; Hansel S
    Biopharm Drug Dispos; 2005 Dec; 26(9):387-402. PubMed ID: 16142720
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cellular models for ADMET predictions and evaluation of drug-drug interactions.
    Riley RJ; Kenna JG
    Curr Opin Drug Discov Devel; 2004 Jan; 7(1):86-99. PubMed ID: 14982152
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Improving compound quality through in vitro and in silico physicochemical profiling.
    van de Waterbeemd H
    Chem Biodivers; 2009 Nov; 6(11):1760-6. PubMed ID: 19937820
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prediction of pharmacokinetics and drug-drug interactions from in vitro metabolism data.
    Shou M
    Curr Opin Drug Discov Devel; 2005 Jan; 8(1):66-77. PubMed ID: 15679174
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mice as clinically relevant models for the study of cytochrome P450-dependent metabolism.
    Muruganandan S; Sinal CJ
    Clin Pharmacol Ther; 2008 Jun; 83(6):818-28. PubMed ID: 18388875
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MetaSite: understanding metabolism in human cytochromes from the perspective of the chemist.
    Cruciani G; Carosati E; De Boeck B; Ethirajulu K; Mackie C; Howe T; Vianello R
    J Med Chem; 2005 Nov; 48(22):6970-9. PubMed ID: 16250655
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of water deprivation on drug pharmacokinetics: correlation between drug metabolism and hepatic CYP isozymes.
    Lee JH; Oh JM; Lee MG
    Arch Pharm Res; 2008 Aug; 31(8):951-64. PubMed ID: 18787780
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High-throughput screening in drug metabolism and pharmacokinetic support of drug discovery.
    White RE
    Annu Rev Pharmacol Toxicol; 2000; 40():133-57. PubMed ID: 10836130
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Designing better drugs: predicting cytochrome P450 metabolism.
    de Groot MJ
    Drug Discov Today; 2006 Jul; 11(13-14):601-6. PubMed ID: 16793528
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.