These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

372 related articles for article (PubMed ID: 21488093)

  • 1. Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo.
    Umeda T; Tomiyama T; Sakama N; Tanaka S; Lambert MP; Klein WL; Mori H
    J Neurosci Res; 2011 Jul; 89(7):1031-42. PubMed ID: 21488093
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypercholesterolemia accelerates intraneuronal accumulation of Aβ oligomers resulting in memory impairment in Alzheimer's disease model mice.
    Umeda T; Tomiyama T; Kitajima E; Idomoto T; Nomura S; Lambert MP; Klein WL; Mori H
    Life Sci; 2012 Dec; 91(23-24):1169-76. PubMed ID: 22273754
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intracellular accumulation of toxic turn amyloid-β is associated with endoplasmic reticulum stress in Alzheimer's disease.
    Soejima N; Ohyagi Y; Nakamura N; Himeno E; Iinuma KM; Sakae N; Yamasaki R; Tabira T; Murakami K; Irie K; Kinoshita N; LaFerla FM; Kiyohara Y; Iwaki T; Kira J
    Curr Alzheimer Res; 2013 Jan; 10(1):11-20. PubMed ID: 22950910
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Amyloid beta oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors.
    Alberdi E; Sánchez-Gómez MV; Cavaliere F; Pérez-Samartín A; Zugaza JL; Trullas R; Domercq M; Matute C
    Cell Calcium; 2010 Mar; 47(3):264-72. PubMed ID: 20061018
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alzheimer's disease amyloid β-protein mutations and deletions that define neuronal binding/internalization as early stage nonfibrillar/fibrillar aggregates and late stage fibrils.
    Poduslo JF; Howell KG; Olson NC; Ramirez-Alvarado M; Kandimalla KK
    Biochemistry; 2012 May; 51(19):3993-4003. PubMed ID: 22545812
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protective effects of [Gly14]-Humanin on beta-amyloid-induced PC12 cell death by preventing mitochondrial dysfunction.
    Jin H; Liu T; Wang WX; Xu JH; Yang PB; Lu HX; Sun QR; Hu HT
    Neurochem Int; 2010 Feb; 56(3):417-23. PubMed ID: 19941922
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hippocampal GABAergic neurons are susceptible to amyloid-β toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model.
    Krantic S; Isorce N; Mechawar N; Davoli MA; Vignault E; Albuquerque M; Chabot JG; Moyse E; Chauvin JP; Aubert I; McLaurin J; Quirion R
    J Alzheimers Dis; 2012; 29(2):293-308. PubMed ID: 22232004
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The E693Δ (Osaka) mutation in amyloid precursor protein potentiates cholesterol-mediated intracellular amyloid β toxicity via its impaired cholesterol efflux.
    Nomura S; Umeda T; Tomiyama T; Mori H
    J Neurosci Res; 2013 Dec; 91(12):1541-50. PubMed ID: 24105984
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proteomic analysis of the brain tissues from a transgenic mouse model of amyloid β oligomers.
    Takano M; Maekura K; Otani M; Sano K; Nakamura-Hirota T; Tokuyama S; Min KS; Tomiyama T; Mori H; Matsuyama S
    Neurochem Int; 2012 Aug; 61(3):347-55. PubMed ID: 22634250
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Intracellular Aß triggers neuron loss in the cholinergic system of the APP/PS1KI mouse model of Alzheimer's disease.
    Christensen DZ; Bayer TA; Wirths O
    Neurobiol Aging; 2010 Jul; 31(7):1153-63. PubMed ID: 18771817
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transient intraneuronal A beta rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice.
    Christensen DZ; Kraus SL; Flohr A; Cotel MC; Wirths O; Bayer TA
    Acta Neuropathol; 2008 Dec; 116(6):647-55. PubMed ID: 18974993
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
    Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.
    Pihlaja R; Koistinaho J; Malm T; Sikkilä H; Vainio S; Koistinaho M
    Glia; 2008 Jan; 56(2):154-63. PubMed ID: 18004725
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction.
    Takuma K; Yao J; Huang J; Xu H; Chen X; Luddy J; Trillat AC; Stern DM; Arancio O; Yan SS
    FASEB J; 2005 Apr; 19(6):597-8. PubMed ID: 15665036
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Early intraneuronal Abeta deposition in the hippocampus of APP transgenic mice.
    Shie FS; LeBoeuf RC; Jin LW
    Neuroreport; 2003 Jan; 14(1):123-9. PubMed ID: 12544843
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glycyrrhiza and Uncaria Hook contribute to protective effect of traditional Japanese medicine yokukansan against amyloid β oligomer-induced neuronal death.
    Kanno H; Kawakami Z; Iizuka S; Tabuchi M; Mizoguchi K; Ikarashi Y; Kase Y
    J Ethnopharmacol; 2013 Aug; 149(1):360-70. PubMed ID: 23838475
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease.
    Jawhar S; Trawicka A; Jenneckens C; Bayer TA; Wirths O
    Neurobiol Aging; 2012 Jan; 33(1):196.e29-40. PubMed ID: 20619937
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of mitochondrial cytochrome c oxidase potentiates Aβ-induced ER stress and cell death in cortical neurons.
    Costa RO; Ferreiro E; Oliveira CR; Pereira CM
    Mol Cell Neurosci; 2013 Jan; 52():1-8. PubMed ID: 23026561
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Endoplasmic reticulum chaperones inhibit the production of amyloid-beta peptides.
    Hoshino T; Nakaya T; Araki W; Suzuki K; Suzuki T; Mizushima T
    Biochem J; 2007 Mar; 402(3):581-9. PubMed ID: 17132139
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells.
    Nishitsuji K; Tomiyama T; Ishibashi K; Ito K; Teraoka R; Lambert MP; Klein WL; Mori H
    Am J Pathol; 2009 Mar; 174(3):957-69. PubMed ID: 19164507
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.