288 related articles for article (PubMed ID: 21489988)
1. Domain 3 of NS5A protein from the hepatitis C virus has intrinsic alpha-helical propensity and is a substrate of cyclophilin A.
Verdegem D; Badillo A; Wieruszeski JM; Landrieu I; Leroy A; Bartenschlager R; Penin F; Lippens G; Hanoulle X
J Biol Chem; 2011 Jun; 286(23):20441-54. PubMed ID: 21489988
[TBL] [Abstract][Full Text] [Related]
2. Hepatitis C virus NS5A protein is a substrate for the peptidyl-prolyl cis/trans isomerase activity of cyclophilins A and B.
Hanoulle X; Badillo A; Wieruszeski JM; Verdegem D; Landrieu I; Bartenschlager R; Penin F; Lippens G
J Biol Chem; 2009 May; 284(20):13589-13601. PubMed ID: 19297321
[TBL] [Abstract][Full Text] [Related]
3. Hepatitis C virus NS5B and host cyclophilin A share a common binding site on NS5A.
Rosnoblet C; Fritzinger B; Legrand D; Launay H; Wieruszeski JM; Lippens G; Hanoulle X
J Biol Chem; 2012 Dec; 287(53):44249-60. PubMed ID: 23152499
[TBL] [Abstract][Full Text] [Related]
4. Overall Structural Model of NS5A Protein from Hepatitis C Virus and Modulation by Mutations Confering Resistance of Virus Replication to Cyclosporin A.
Badillo A; Receveur-Brechot V; Sarrazin S; Cantrelle FX; Delolme F; Fogeron ML; Molle J; Montserret R; Bockmann A; Bartenschlager R; Lohmann V; Lippens G; Ricard-Blum S; Hanoulle X; Penin F
Biochemistry; 2017 Jun; 56(24):3029-3048. PubMed ID: 28535337
[TBL] [Abstract][Full Text] [Related]
5. A Proline-Tryptophan Turn in the Intrinsically Disordered Domain 2 of NS5A Protein Is Essential for Hepatitis C Virus RNA Replication.
Dujardin M; Madan V; Montserret R; Ahuja P; Huvent I; Launay H; Leroy A; Bartenschlager R; Penin F; Lippens G; Hanoulle X
J Biol Chem; 2015 Jul; 290(31):19104-20. PubMed ID: 26085105
[TBL] [Abstract][Full Text] [Related]
6. HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors.
Chatterji U; Lim P; Bobardt MD; Wieland S; Cordek DG; Vuagniaux G; Chisari F; Cameron CE; Targett-Adams P; Parkinson T; Gallay PA
J Hepatol; 2010 Jul; 53(1):50-6. PubMed ID: 20451281
[TBL] [Abstract][Full Text] [Related]
7. Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication.
Dujardin M; Madan V; Gandhi NS; Cantrelle FX; Launay H; Huvent I; Bartenschlager R; Lippens G; Hanoulle X
J Biol Chem; 2019 Aug; 294(35):13171-13185. PubMed ID: 31315928
[TBL] [Abstract][Full Text] [Related]
8. ISGylation of Hepatitis C Virus NS5A Protein Promotes Viral RNA Replication via Recruitment of Cyclophilin A.
Abe T; Minami N; Bawono RG; Matsui C; Deng L; Fukuhara T; Matsuura Y; Shoji I
J Virol; 2020 Sep; 94(20):. PubMed ID: 32727878
[TBL] [Abstract][Full Text] [Related]
9. A conserved tandem cyclophilin-binding site in hepatitis C virus nonstructural protein 5A regulates Alisporivir susceptibility.
Grisé H; Frausto S; Logan T; Tang H
J Virol; 2012 May; 86(9):4811-22. PubMed ID: 22345441
[TBL] [Abstract][Full Text] [Related]
10. Domain 3 of non-structural protein 5A from hepatitis C virus is natively unfolded.
Hanoulle X; Verdegem D; Badillo A; Wieruszeski JM; Penin F; Lippens G
Biochem Biophys Res Commun; 2009 Apr; 381(4):634-8. PubMed ID: 19249289
[TBL] [Abstract][Full Text] [Related]
11. A major determinant of cyclophilin dependence and cyclosporine susceptibility of hepatitis C virus identified by a genetic approach.
Yang F; Robotham JM; Grise H; Frausto S; Madan V; Zayas M; Bartenschlager R; Robinson M; Greenstein AE; Nag A; Logan TM; Bienkiewicz E; Tang H
PLoS Pathog; 2010 Sep; 6(9):e1001118. PubMed ID: 20886100
[TBL] [Abstract][Full Text] [Related]
12. The C terminus of NS5A domain II is a key determinant of hepatitis C virus genome replication, but is not required for virion assembly and release.
Ross-Thriepland D; Amako Y; Harris M
J Gen Virol; 2013 May; 94(Pt 5):1009-1018. PubMed ID: 23324467
[TBL] [Abstract][Full Text] [Related]
13. The cyclophilin inhibitor SCY-635 disrupts hepatitis C virus NS5A-cyclophilin A complexes.
Hopkins S; Bobardt M; Chatterji U; Garcia-Rivera JA; Lim P; Gallay PA
Antimicrob Agents Chemother; 2012 Jul; 56(7):3888-97. PubMed ID: 22585215
[TBL] [Abstract][Full Text] [Related]
14. Interactions of the Disordered Domain II of Hepatitis C Virus NS5A with Cyclophilin A, NS5B, and Viral RNA Show Extensive Overlap.
Ngure M; Issur M; Shkriabai N; Liu HW; Cosa G; Kvaratskhelia M; Götte M
ACS Infect Dis; 2016 Nov; 2(11):839-851. PubMed ID: 27676132
[TBL] [Abstract][Full Text] [Related]
15. The use of AlphaLISA technology to detect interaction between hepatitis C virus-encoded NS5A and cyclophilin A.
Waller H; Chatterji U; Gallay P; Parkinson T; Targett-Adams P
J Virol Methods; 2010 May; 165(2):202-10. PubMed ID: 20132841
[TBL] [Abstract][Full Text] [Related]
16. DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A.
Coelmont L; Hanoulle X; Chatterji U; Berger C; Snoeck J; Bobardt M; Lim P; Vliegen I; Paeshuyse J; Vuagniaux G; Vandamme AM; Bartenschlager R; Gallay P; Lippens G; Neyts J
PLoS One; 2010 Oct; 5(10):e13687. PubMed ID: 21060866
[TBL] [Abstract][Full Text] [Related]
17. HCV NS5A and IRF9 compete for CypA binding.
Bobardt M; Hopkins S; Baugh J; Chatterji U; Hernandez F; Hiscott J; Sluder A; Lin K; Gallay PA
J Hepatol; 2013 Jan; 58(1):16-23. PubMed ID: 22902549
[TBL] [Abstract][Full Text] [Related]
18. Cyclophilin A interacts with domain II of hepatitis C virus NS5A and stimulates RNA binding in an isomerase-dependent manner.
Foster TL; Gallay P; Stonehouse NJ; Harris M
J Virol; 2011 Jul; 85(14):7460-4. PubMed ID: 21593166
[TBL] [Abstract][Full Text] [Related]
19. Domain 2 of nonstructural protein 5A (NS5A) of hepatitis C virus is natively unfolded.
Liang Y; Ye H; Kang CB; Yoon HS
Biochemistry; 2007 Oct; 46(41):11550-8. PubMed ID: 17880107
[TBL] [Abstract][Full Text] [Related]
20. Mutational analysis reveals a novel role for hepatitis C virus NS5A domain I in cyclophilin-dependent genome replication.
Chen S; Harris M
J Gen Virol; 2023 Sep; 104(9):. PubMed ID: 37672027
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
