233 related articles for article (PubMed ID: 21490315)
1. Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER.
Smith JL; McBride CM; Nataraj PS; Bartos DC; January CT; Delisle BP
Am J Physiol Cell Physiol; 2011 Jul; 301(1):C75-85. PubMed ID: 21490315
[TBL] [Abstract][Full Text] [Related]
2. Pharmacological correction of long QT-linked mutations in KCNH2 (hERG) increases the trafficking of Kv11.1 channels stored in the transitional endoplasmic reticulum.
Smith JL; Reloj AR; Nataraj PS; Bartos DC; Schroder EA; Moss AJ; Ohno S; Horie M; Anderson CL; January CT; Delisle BP
Am J Physiol Cell Physiol; 2013 Nov; 305(9):C919-30. PubMed ID: 23864605
[TBL] [Abstract][Full Text] [Related]
3. The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.
Ficker E; Obejero-Paz CA; Zhao S; Brown AM
J Biol Chem; 2002 Feb; 277(7):4989-98. PubMed ID: 11741928
[TBL] [Abstract][Full Text] [Related]
4. Properties of WT and mutant hERG K(+) channels expressed in neonatal mouse cardiomyocytes.
Lin EC; Holzem KM; Anson BD; Moungey BM; Balijepalli SY; Tester DJ; Ackerman MJ; Delisle BP; Balijepalli RC; January CT
Am J Physiol Heart Circ Physiol; 2010 Jun; 298(6):H1842-9. PubMed ID: 20363883
[TBL] [Abstract][Full Text] [Related]
5. Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndrome.
Gong Q; Jones MA; Zhou Z
J Biol Chem; 2006 Feb; 281(7):4069-74. PubMed ID: 16361248
[TBL] [Abstract][Full Text] [Related]
6. Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C.
Delisle BP; Anderson CL; Balijepalli RC; Anson BD; Kamp TJ; January CT
J Biol Chem; 2003 Sep; 278(37):35749-54. PubMed ID: 12837749
[TBL] [Abstract][Full Text] [Related]
7. Visualizing Mutation-Specific Differences in the Trafficking-Deficient Phenotype of Kv11.1 Proteins Linked to Long QT Syndrome Type 2.
Hall AR; Anderson CL; Smith JL; Mirshahi T; Elayi CS; January CT; Delisle BP
Front Physiol; 2018; 9():584. PubMed ID: 29875689
[No Abstract] [Full Text] [Related]
8. Small GTPase determinants for the Golgi processing and plasmalemmal expression of human ether-a-go-go related (hERG) K+ channels.
Delisle BP; Underkofler HAS; Moungey BM; Slind JK; Kilby JA; Best JM; Foell JD; Balijepalli RC; Kamp TJ; January CT
J Biol Chem; 2009 Jan; 284(5):2844-2853. PubMed ID: 19029296
[TBL] [Abstract][Full Text] [Related]
9. Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel.
Furutani M; Trudeau MC; Hagiwara N; Seki A; Gong Q; Zhou Z; Imamura S; Nagashima H; Kasanuki H; Takao A; Momma K; January CT; Robertson GA; Matsuoka R
Circulation; 1999 May; 99(17):2290-4. PubMed ID: 10226095
[TBL] [Abstract][Full Text] [Related]
10. Novel characteristics of a trafficking-defective G572R-hERG channel linked to hereditary long QT syndrome.
Lian J; Huang N; Zhou J; Ge S; Huang X; Huo J; Liu L; Xu W; Zhang S; Yang X; Zhou J; Huang C
Can J Cardiol; 2010 Oct; 26(8):417-22. PubMed ID: 20931094
[TBL] [Abstract][Full Text] [Related]
11. Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism.
Anderson CL; Delisle BP; Anson BD; Kilby JA; Will ML; Tester DJ; Gong Q; Zhou Z; Ackerman MJ; January CT
Circulation; 2006 Jan; 113(3):365-73. PubMed ID: 16432067
[TBL] [Abstract][Full Text] [Related]
12. Differential Effects of Remdesivir and Lumacaftor on Homomeric and Heteromeric hERG Channels.
Campagna N; Wall E; Lee K; Guo J; Li W; Yang T; Baranchuk A; El-Diasty M; Zhang S
Mol Pharmacol; 2023 Oct; 104(4):164-173. PubMed ID: 37419691
[TBL] [Abstract][Full Text] [Related]
13. Trafficking-deficient G572R-hERG and E637K-hERG activate stress and clearance pathways in endoplasmic reticulum.
Wang Y; Huang X; Zhou J; Yang X; Li D; Mao H; Sun HH; Liu N; Lian J
PLoS One; 2012; 7(1):e29885. PubMed ID: 22242185
[TBL] [Abstract][Full Text] [Related]
14. Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects.
Zhou Z; Gong Q; January CT
J Biol Chem; 1999 Oct; 274(44):31123-6. PubMed ID: 10531299
[TBL] [Abstract][Full Text] [Related]
15. Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether-à-go-go-Related Gene.
Roti EC; Myers CD; Ayers RA; Boatman DE; Delfosse SA; Chan EK; Ackerman MJ; January CT; Robertson GA
J Biol Chem; 2002 Dec; 277(49):47779-85. PubMed ID: 12270925
[TBL] [Abstract][Full Text] [Related]
16. Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-á-go-go-related gene potassium channels.
Gianulis EC; Trudeau MC
J Biol Chem; 2011 Jun; 286(25):22160-9. PubMed ID: 21536673
[TBL] [Abstract][Full Text] [Related]
17. HERG-F463L potassium channels linked to long QT syndrome reduce I(Kr) current by a trafficking-deficient mechanism.
Yang HT; Sun CF; Cui CC; Xue XL; Zhang AF; Li HB; Wang DQ; Shu J
Clin Exp Pharmacol Physiol; 2009 Aug; 36(8):822-7. PubMed ID: 19215240
[TBL] [Abstract][Full Text] [Related]
18. Regulation of the human ether-a-go-go-related gene (hERG) potassium channel by Nedd4 family interacting proteins (Ndfips).
Kang Y; Guo J; Yang T; Li W; Zhang S
Biochem J; 2015 Nov; 472(1):71-82. PubMed ID: 26363003
[TBL] [Abstract][Full Text] [Related]
19. hERG quality control and the long QT syndrome.
Foo B; Williamson B; Young JC; Lukacs G; Shrier A
J Physiol; 2016 May; 594(9):2469-81. PubMed ID: 26718903
[TBL] [Abstract][Full Text] [Related]
20. LQT2 nonsense mutations generate trafficking defective NH2-terminally truncated channels by the reinitiation of translation.
Stump MR; Gong Q; Zhou Z
Am J Physiol Heart Circ Physiol; 2013 Nov; 305(9):H1397-404. PubMed ID: 23997099
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
