BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 21490615)

  • 1. Chemical chaperones protect epidermolysis bullosa simplex keratinocytes from heat stress-induced keratin aggregation: involvement of heat shock proteins and MAP kinases.
    Chamcheu JC; Navsaria H; Pihl-Lundin I; Liovic M; Vahlquist A; Törmä H
    J Invest Dermatol; 2011 Aug; 131(8):1684-91. PubMed ID: 21490615
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of immortalized human epidermolysis bullosa simplex (KRT5) cell lines: trimethylamine N-oxide protects the keratin cytoskeleton against disruptive stress condition.
    Chamcheu JC; Lorié EP; Akgul B; Bannbers E; Virtanen M; Gammon L; Moustakas A; Navsaria H; Vahlquist A; Törmä H
    J Dermatol Sci; 2009 Mar; 53(3):198-206. PubMed ID: 19157792
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Epidermolysis bullosa simplex due to KRT5 mutations: mutation-related differences in cellular fragility and the protective effects of trimethylamine N-oxide in cultured primary keratinocytes.
    Chamcheu JC; Virtanen M; Navsaria H; Bowden PE; Vahlquist A; Törmä H
    Br J Dermatol; 2010 May; 162(5):980-9. PubMed ID: 20128788
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.
    Löffek S; Wöll S; Höhfeld J; Leube RE; Has C; Bruckner-Tuderman L; Magin TM
    Hum Mutat; 2010 Apr; 31(4):466-76. PubMed ID: 20151404
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ERK involvement in resistance to apoptosis in keratinocytes with mutant keratin.
    Russell D; Ross H; Lane EB
    J Invest Dermatol; 2010 Mar; 130(3):671-81. PubMed ID: 19847192
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reduction in keratin aggregates in epidermolysis bullosa simplex keratinocytes after pretreatment with trimethylamine N-oxide.
    Bchetnia M; Lacroix J; Farez T; Larouche M; Powell J; McCuaig C; Dupéré A; Morin C; Legendre-Guillemin V; Laprise C
    Exp Dermatol; 2016 Mar; 25(3):229-30. PubMed ID: 26264477
    [No Abstract]   [Full Text] [Related]  

  • 7. An autocrine/paracrine loop linking keratin 14 aggregates to tumor necrosis factor alpha-mediated cytotoxicity in a keratinocyte model of epidermolysis bullosa simplex.
    Yoneda K; Furukawa T; Zheng YJ; Momoi T; Izawa I; Inagaki M; Manabe M; Inagaki N
    J Biol Chem; 2004 Feb; 279(8):7296-303. PubMed ID: 14660619
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex.
    Evtushenko NA; Beilin AK; Kosykh AV; Vorotelyak EA; Gurskaya NG
    Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830328
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Generation and characterization of epidermolysis bullosa simplex cell lines: scratch assays show faster migration with disruptive keratin mutations.
    Morley SM; D'Alessandro M; Sexton C; Rugg EL; Navsaria H; Shemanko CS; Huber M; Hohl D; Heagerty AI; Leigh IM; Lane EB
    Br J Dermatol; 2003 Jul; 149(1):46-58. PubMed ID: 12890194
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Keratin mutations in patients with epidermolysis bullosa simplex: correlations between phenotype severity and disturbance of intermediate filament molecular structure.
    Jerábková B; Marek J; Bucková H; Kopecková L; Veselý K; Valícková J; Fajkus J; Fajkusová L
    Br J Dermatol; 2010 May; 162(5):1004-13. PubMed ID: 20030639
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional testing of keratin 14 mutant proteins associated with the three major subtypes of epidermolysis bullosa simplex.
    Sørensen CB; Andresen BS; Jensen UB; Jensen TG; Jensen PK; Gregersen N; Bolund L
    Exp Dermatol; 2003 Aug; 12(4):472-9. PubMed ID: 12930305
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Treatment of keratinocytes with 4-phenylbutyrate in epidermolysis bullosa: Lessons for therapies in keratin disorders.
    Spörrer M; Prochnicki A; Tölle RC; Nyström A; Esser PR; Homberg M; Athanasiou I; Zingkou E; Schilling A; Gerum R; Thievessen I; Winter L; Bruckner-Tuderman L; Fabry B; Magin TM; Dengjel J; Schröder R; Kiritsi D
    EBioMedicine; 2019 Jun; 44():502-515. PubMed ID: 31078522
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Threonine 150 Phosphorylation of Keratin 5 Is Linked to Epidermolysis Bullosa Simplex and Regulates Filament Assembly and Cell Viability.
    Sawant M; Schwarz N; Windoffer R; Magin TM; Krieger J; Mücke N; Obara B; Jankowski V; Jankowski J; Wally V; Lettner T; Leube RE
    J Invest Dermatol; 2018 Mar; 138(3):627-636. PubMed ID: 29080682
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A cell-based drug discovery assay identifies inhibition of cell stress responses as a new approach to treatment of epidermolysis bullosa simplex.
    Tan TS; Common JEA; Lim JSY; Badowski C; Firdaus MJ; Leonardi SS; Lane EB
    J Cell Sci; 2021 Oct; 134(19):. PubMed ID: 34643242
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutation analysis of the entire keratin 5 and 14 genes in patients with epidermolysis bullosa simplex and identification of novel mutations.
    Schuilenga-Hut PH; Vlies Pv; Jonkman MF; Waanders E; Buys CH; Scheffer H
    Hum Mutat; 2003 Apr; 21(4):447. PubMed ID: 12655565
    [TBL] [Abstract][Full Text] [Related]  

  • 16. JNK phosphorylates the HSF1 transcriptional activation domain: role of JNK in the regulation of the heat shock response.
    Park J; Liu AY
    J Cell Biochem; 2001; 82(2):326-38. PubMed ID: 11527157
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proteasome-mediated degradation of keratins 7, 8, 17 and 18 by mutant KLHL24 in a foetal keratinocyte model: Novel insight in congenital skin defects and fragility of epidermolysis bullosa simplex with cardiomyopathy.
    Logli E; Marzuolo E; D'Agostino M; Conti LA; Lena AM; Diociaiuti A; Dellambra E; Has C; Cianfanelli V; Zambruno G; El Hachem M; Magenta A; Candi E; Condorelli AG
    Hum Mol Genet; 2022 Apr; 31(8):1308-1324. PubMed ID: 34740256
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Drosophila Model of Epidermolysis Bullosa Simplex.
    Bohnekamp J; Cryderman DE; Paululat A; Baccam GC; Wallrath LL; Magin TM
    J Invest Dermatol; 2015 Aug; 135(8):2031-2039. PubMed ID: 25830653
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutations in KRT5 and KRT14 cause epidermolysis bullosa simplex in 75% of the patients.
    Bolling MC; Lemmink HH; Jansen GH; Jonkman MF
    Br J Dermatol; 2011 Mar; 164(3):637-44. PubMed ID: 21375516
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel and recurrent mutations in keratin KRT5 and KRT14 genes in epidermolysis bullosa simplex: implications for disease phenotype and keratin filament assembly.
    Müller FB; Küster W; Wodecki K; Almeida H; Bruckner-Tuderman L; Krieg T; Korge BP; Arin MJ
    Hum Mutat; 2006 Jul; 27(7):719-20. PubMed ID: 16786515
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.