These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 21495633)

  • 1. Double oxidation of the cyclic nonaketide dihydromonacolin L to monacolin J by a single cytochrome P450 monooxygenase, LovA.
    Barriuso J; Nguyen DT; Li JW; Roberts JN; MacNevin G; Chaytor JL; Marcus SL; Vederas JC; Ro DK
    J Am Chem Soc; 2011 Jun; 133(21):8078-81. PubMed ID: 21495633
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transformations of cyclic nonaketides by Aspergillus terreus mutants blocked for lovastatin biosynthesis at the lovA and lovC genes.
    Sorensen JL; Auclair K; Kennedy J; Hutchinson CR; Vederas JC
    Org Biomol Chem; 2003 Jan; 1(1):50-9. PubMed ID: 12929390
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aspects of the biosynthesis of non-aromatic fungal polyketides by iterative polyketide synthases.
    Hutchinson CR; Kennedy J; Park C; Kendrew S; Auclair K; Vederas J
    Antonie Van Leeuwenhoek; 2000 Dec; 78(3-4):287-95. PubMed ID: 11386351
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis.
    Kennedy J; Auclair K; Kendrew SG; Park C; Vederas JC; Hutchinson CR
    Science; 1999 May; 284(5418):1368-72. PubMed ID: 10334994
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Construction of an Efficient and Robust Aspergillus terreus Cell Factory for Monacolin J Production.
    Huang X; Tang S; Zheng L; Teng Y; Yang Y; Zhu J; Lu X
    ACS Synth Biol; 2019 Apr; 8(4):818-825. PubMed ID: 30856313
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced Single-Step Bioproduction of the Simvastatin Precursor Monacolin J in an Industrial Strain of Aspergillus terreus by Employing the Evolved Lovastatin Hydrolase.
    Liang B; Huang X; Teng Y; Liang Y; Yang Y; Zheng L; Lu X
    Biotechnol J; 2018 Jun; 13(6):e1800094. PubMed ID: 29637704
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Single-step production of the simvastatin precursor monacolin J by engineering of an industrial strain of Aspergillus terreus.
    Huang X; Liang Y; Yang Y; Lu X
    Metab Eng; 2017 Jul; 42():109-114. PubMed ID: 28619444
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Engineered monoculture and co-culture of methylotrophic yeast for de novo production of monacolin J and lovastatin from methanol.
    Liu Y; Tu X; Xu Q; Bai C; Kong C; Liu Q; Yu J; Peng Q; Zhou X; Zhang Y; Cai M
    Metab Eng; 2018 Jan; 45():189-199. PubMed ID: 29258964
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Complete reconstitution of a highly reducing iterative polyketide synthase.
    Ma SM; Li JW; Choi JW; Zhou H; Lee KK; Moorthie VA; Xie X; Kealey JT; Da Silva NA; Vederas JC; Tang Y
    Science; 2009 Oct; 326(5952):589-92. PubMed ID: 19900898
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Syntheses of conjugated pyrones for the enzymatic assay of lovastatin nonaketide synthase, an iterative polyketide synthase.
    Burr DA; Chen XB; Vederas JC
    Org Lett; 2007 Jan; 9(1):161-4. PubMed ID: 17192110
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Origin of monacolin L from Aspergillus terreus cultures.
    Treiber LR; Reamer RA; Rooney CS; Ramjit HG
    J Antibiot (Tokyo); 1989 Jan; 42(1):30-6. PubMed ID: 2921224
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Engineering Saccharomyces cerevisiae for production of simvastatin.
    Bond CM; Tang Y
    Metab Eng; 2019 Jan; 51():1-8. PubMed ID: 30213650
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for the biosynthesis of lovastatin.
    Wang J; Liang J; Chen L; Zhang W; Kong L; Peng C; Su C; Tang Y; Deng Z; Wang Z
    Nat Commun; 2021 Feb; 12(1):867. PubMed ID: 33558520
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of phenobarbital-inducible cytochrome P450 2B1/2 mRNA by lovastatin and oxysterols in primary cultures of adult rat hepatocytes.
    Kocarek TA; Schuetz EG; Guzelian PS
    Toxicol Appl Pharmacol; 1993 Jun; 120(2):298-307. PubMed ID: 8511800
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biosynthesis of monacolins: conversion of monacolin L to monacolin J by a monooxygenase of Monascus ruber.
    Komagata D; Shimada H; Murakawa S; Endo A
    J Antibiot (Tokyo); 1989 Mar; 42(3):407-12. PubMed ID: 2708134
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biochemical characterization of the minimal polyketide synthase domains in the lovastatin nonaketide synthase LovB.
    Ma SM; Tang Y
    FEBS J; 2007 Jun; 274(11):2854-64. PubMed ID: 17466016
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An overview on the biosynthesis and metabolic regulation of monacolin K/lovastatin.
    Zhang Y; Chen Z; Wen Q; Xiong Z; Cao X; Zheng Z; Zhang Y; Huang Z
    Food Funct; 2020 Jul; 11(7):5738-5748. PubMed ID: 32555902
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conversion of cyclic nonaketides to lovastatin and compactin by a lovC deficient mutant of Aspergillus terreus.
    Auclair K; Kennedy J; Hutchinson CR; Vederas JC
    Bioorg Med Chem Lett; 2001 Jun; 11(12):1527-31. PubMed ID: 11412974
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Monacolin N, a compound resulting from derailment of type I iterative polyketide synthase function en route to lovastatin.
    Sorensen JL; Vederas JC
    Chem Commun (Camb); 2003 Jul; (13):1492-3. PubMed ID: 12868719
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biotechnological production and applications of statins.
    Barrios-González J; Miranda RU
    Appl Microbiol Biotechnol; 2010 Jan; 85(4):869-83. PubMed ID: 19820926
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.