167 related articles for article (PubMed ID: 21495724)
1. Molecular modeling and molecular dynamics simulation studies of the GSK3β/ATP/substrate complex: understanding the unique P+4 primed phosphorylation specificity for GSK3β substrates.
Lu SY; Jiang YJ; Zou JW; Wu TX
J Chem Inf Model; 2011 May; 51(5):1025-36. PubMed ID: 21495724
[TBL] [Abstract][Full Text] [Related]
2. Structural basis for the complete loss of GSK3beta catalytic activity due to R96 mutation investigated by molecular dynamics study.
Zhang N; Jiang Y; Zou J; Yu Q; Zhao W
Proteins; 2009 May; 75(3):671-81. PubMed ID: 19003984
[TBL] [Abstract][Full Text] [Related]
3. How calcium inhibits the magnesium-dependent kinase gsk3β: a molecular simulation study.
Lu SY; Huang ZM; Huang WK; Liu XY; Chen YY; Shi T; Zhang J
Proteins; 2013 May; 81(5):740-53. PubMed ID: 23184735
[TBL] [Abstract][Full Text] [Related]
4. Effect of double mutations K214/A-E215/Q of FRATide on GSK3β: insights from molecular dynamics simulation and normal mode analysis.
Lu SY; Jiang YJ; Zou JW; Wu TX
Amino Acids; 2012 Jul; 43(1):267-77. PubMed ID: 21912861
[TBL] [Abstract][Full Text] [Related]
5. Homology modeling and molecular dynamics study of GSK3/SHAGGY-like kinase.
Xiao JF; Li ZS; Sun M; Zhang Y; Sun CC
Comput Biol Chem; 2004 Jul; 28(3):179-88. PubMed ID: 15261148
[TBL] [Abstract][Full Text] [Related]
6. Mechanism of kinase inactivation and nonbinding of FRATide to GSK3β due to K85M mutation: molecular dynamics simulation and normal mode analysis.
Lu S; Jiang Y; Lv J; Zou J; Wu T
Biopolymers; 2011 Oct; 95(10):669-81. PubMed ID: 21442609
[TBL] [Abstract][Full Text] [Related]
7. Structure of GSK3beta reveals a primed phosphorylation mechanism.
ter Haar E; Coll JT; Austen DA; Hsiao HM; Swenson L; Jain J
Nat Struct Biol; 2001 Jul; 8(7):593-6. PubMed ID: 11427888
[TBL] [Abstract][Full Text] [Related]
8. Microsecond molecular dynamics simulations and dynamic network analysis provide understanding of the allosteric inactivation of GSK3β induced by the L343R mutation.
Li J; Fu Q; Liang Y; Cheng B; Li X
J Mol Model; 2019 Apr; 25(5):111. PubMed ID: 30949773
[TBL] [Abstract][Full Text] [Related]
9. Unraveling the role of Arg4 and Arg6 in the auto-inhibition mechanism of GSK3β from molecular dynamics simulation.
Mou L; Li M; Lu SY; Li S; Shen Q; Zhang J; Li C; Lu X
Chem Biol Drug Des; 2014 Jun; 83(6):721-30. PubMed ID: 24444018
[TBL] [Abstract][Full Text] [Related]
10. Dissection of the difference between the group I metal ions in inhibiting GSK3β: a computational study.
Lu SY; Jiang YJ; Zou JW; Wu TX
Phys Chem Chem Phys; 2011 Apr; 13(15):7014-23. PubMed ID: 21409189
[TBL] [Abstract][Full Text] [Related]
11. The structural basis of the autoinhibition mechanism of glycogen synthase kinase 3β (GSK3β): molecular modeling and molecular dynamics simulation studies.
Mou L; Dou W; Meng G; Sun K; Chen X
J Biomol Struct Dyn; 2020 Apr; 38(6):1741-1750. PubMed ID: 31057052
[TBL] [Abstract][Full Text] [Related]
12. P2 purinergic receptors signal to glycogen synthase kinase-3beta in astrocytes.
Neary JT; Kang Y
J Neurosci Res; 2006 Aug; 84(3):515-24. PubMed ID: 16810687
[TBL] [Abstract][Full Text] [Related]
13. Molecular dynamics simulation studies of GSK-3β ATP competitive inhibitors: understanding the factors contributing to selectivity.
Arfeen M; Patel R; Khan T; Bharatam PV
J Biomol Struct Dyn; 2015; 33(12):2578-93. PubMed ID: 26209183
[TBL] [Abstract][Full Text] [Related]
14. Using thermodynamic integration MD simulation to compute relative protein-ligand binding free energy of a GSK3β kinase inhibitor and its analogs.
Lee HC; Hsu WC; Liu AL; Hsu CJ; Sun YC
J Mol Graph Model; 2014 Jun; 51():37-49. PubMed ID: 24858254
[TBL] [Abstract][Full Text] [Related]
15. Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP.
Yang J; Cron P; Good VM; Thompson V; Hemmings BA; Barford D
Nat Struct Biol; 2002 Dec; 9(12):940-4. PubMed ID: 12434148
[TBL] [Abstract][Full Text] [Related]
16. Xanthone glucoside 2-β-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one binds to the ATP-binding pocket of glycogen synthase kinase 3β and inhibits its activity: implications in prostate cancer and associated cardiovascular disease risk.
Mangangcha IR; Brojen Singh RK; Lebeche D; Ali S
J Biomol Struct Dyn; 2022 Oct; 40(17):7868-7884. PubMed ID: 33769184
[TBL] [Abstract][Full Text] [Related]
17. Theoretical Studies on the Selectivity Mechanisms of Glycogen Synthase Kinase 3β (GSK3β) with Pyrazine ATP-competitive Inhibitors by 3DQSAR, Molecular Docking, Molecular Dynamics Simulation and Free Energy Calculations.
Zhu J; Wu Y; Xu L; Jin J
Curr Comput Aided Drug Des; 2020; 16(1):17-30. PubMed ID: 31284868
[TBL] [Abstract][Full Text] [Related]
18. An ESI-MS/MS method for screening of small-molecule mixtures against glycogen synthase kinase-3beta (GSK-3beta).
Partserniak I; Werstuck G; Capretta A; Brennan JD
Chembiochem; 2008 May; 9(7):1065-73. PubMed ID: 18348127
[TBL] [Abstract][Full Text] [Related]
19. Phosphorylation of heart glycogen synthase by cAMP-dependent protein kinase. Regulatory effects of ATP.
Mitchell JW; Mellgren RL; Thomas JA
J Biol Chem; 1980 Nov; 255(21):10368-74. PubMed ID: 6253472
[TBL] [Abstract][Full Text] [Related]
20. Maintained activity of glycogen synthase kinase-3beta despite of its phosphorylation at serine-9 in okadaic acid-induced neurodegenerative model.
Lim YW; Yoon SY; Choi JE; Kim SM; Lee HS; Choe H; Lee SC; Kim DH
Biochem Biophys Res Commun; 2010 Apr; 395(2):207-12. PubMed ID: 20362550
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]