BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 21501597)

  • 1. Development of screening assays and discovery of initial inhibitors of pneumococcal peptidoglycan deacetylase PgdA.
    Bui NK; Turk S; Buckenmaier S; Stevenson-Jones F; Zeuch B; Gobec S; Vollmer W
    Biochem Pharmacol; 2011 Jul; 82(1):43-52. PubMed ID: 21501597
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Direct Staudinger-Phosphonite Reaction Provides Methylphosphonamidates as Inhibitors of CE4 De-N-acetylases.
    Ariyakumaran R; Pokrovskaya V; Little DJ; Howell PL; Nitz M
    Chembiochem; 2015 Jun; 16(9):1350-6. PubMed ID: 25864869
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The pgdA gene encodes for a peptidoglycan N-acetylglucosamine deacetylase in Streptococcus pneumoniae.
    Vollmer W; Tomasz A
    J Biol Chem; 2000 Jul; 275(27):20496-501. PubMed ID: 10781617
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Screening for antibacterial inhibitors of the UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) using a high-throughput mass spectrometry assay.
    Langsdorf EF; Malikzay A; Lamarr WA; Daubaras D; Kravec C; Zhang R; Hart R; Monsma F; Black T; Ozbal CC; Miesel L; Lunn CA
    J Biomol Screen; 2010 Jan; 15(1):52-61. PubMed ID: 20019290
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Streptococcus pneumononiae gyrase ATPase: development and validation of an assay for inhibitor discovery and characterization.
    Miller JR; Herberg JT; Tomilo M; McCroskey MC; Feilmeier BJ
    Anal Biochem; 2007 Jun; 365(1):132-43. PubMed ID: 17395144
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Peptidoglycan N-acetylglucosamine deacetylase, a putative virulence factor in Streptococcus pneumoniae.
    Vollmer W; Tomasz A
    Infect Immun; 2002 Dec; 70(12):7176-8. PubMed ID: 12438406
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening.
    Miguet L; Zervosen A; Gerards T; Pasha FA; Luxen A; Distèche-Nguyen M; Thomas A
    J Med Chem; 2009 Oct; 52(19):5926-36. PubMed ID: 19746934
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Benzothioxalone derivatives as novel inhibitors of UDP-N-acetylglucosamine enolpyruvyl transferases (MurA and MurZ).
    Miller K; Dunsmore CJ; Leeds JA; Patching SG; Sachdeva M; Blake KL; Stubbings WJ; Simmons KJ; Henderson PJ; De Los Angeles J; Fishwick CW; Chopra I
    J Antimicrob Chemother; 2010 Dec; 65(12):2566-73. PubMed ID: 20861142
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system.
    Boneca IG; Dussurget O; Cabanes D; Nahori MA; Sousa S; Lecuit M; Psylinakis E; Bouriotis V; Hugot JP; Giovannini M; Coyle A; Bertin J; Namane A; Rousselle JC; Cayet N; Prévost MC; Balloy V; Chignard M; Philpott DJ; Cossart P; Girardin SE
    Proc Natl Acad Sci U S A; 2007 Jan; 104(3):997-1002. PubMed ID: 17215377
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and evaluation of second generation MurF inhibitors based on a cyanothiophene scaffold.
    Hrast M; Anderluh M; Knez D; Randall CP; Barreteau H; O'Neill AJ; Blanot D; Gobec S
    Eur J Med Chem; 2014 Feb; 73():83-96. PubMed ID: 24384549
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibitors of Streptococcus pneumoniae surface endonuclease EndA discovered by high-throughput screening using a PicoGreen fluorescence assay.
    Peterson EJ; Kireev D; Moon AF; Midon M; Janzen WP; Pingoud A; Pedersen LC; Singleton SF
    J Biomol Screen; 2013 Mar; 18(3):247-57. PubMed ID: 23015019
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors.
    Giastas P; Andreou A; Papakyriakou A; Koutsioulis D; Balomenou S; Tzartos SJ; Bouriotis V; Eliopoulos EE
    Biochemistry; 2018 Feb; 57(5):753-763. PubMed ID: 29257674
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Monosaccharide inhibitors targeting carbohydrate esterase family 4 de-N-acetylases.
    DiFrancesco BR; Morrison ZA; Nitz M
    Bioorg Med Chem; 2018 Nov; 26(21):5631-5643. PubMed ID: 30344002
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Screening assay for inhibitors of a recombinant Streptococcus pneumoniae UDP-glucose pyrophosphorylase.
    Zavala A; Kovacec V; Levín G; Moglioni A; Miranda MV; García E; Bonofiglio L; Mollerach M
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):203-207. PubMed ID: 28114831
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In silico chemical library screening and experimental validation of a novel 9-aminoacridine based lead-inhibitor of human S-adenosylmethionine decarboxylase.
    Brooks WH; McCloskey DE; Daniel KG; Ealick SE; Secrist JA; Waud WR; Pegg AE; Guida WC
    J Chem Inf Model; 2007; 47(5):1897-905. PubMed ID: 17676832
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of new inhibitors of the bacterial peptidoglycan biosynthesis enzymes MurD and MurF by structure-based virtual screening.
    Turk S; Kovac A; Boniface A; Bostock JM; Chopra I; Blanot D; Gobec S
    Bioorg Med Chem; 2009 Mar; 17(5):1884-9. PubMed ID: 19223185
    [TBL] [Abstract][Full Text] [Related]  

  • 17. AG205, a novel agent directed against FabK of Streptococcus pneumoniae.
    Takahata S; Iida M; Osaki Y; Saito J; Kitagawa H; Ozawa T; Yoshida T; Hoshiko S
    Antimicrob Agents Chemother; 2006 Aug; 50(8):2869-71. PubMed ID: 16870790
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of new inhibitors of D-alanine:D-alanine ligase by structure-based virtual screening.
    Kovac A; Konc J; Vehar B; Bostock JM; Chopra I; Janezic D; Gobec S
    J Med Chem; 2008 Dec; 51(23):7442-8. PubMed ID: 19053785
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Theoretical study of Escherichia coli peptide deformylase inhibition by several drugs.
    Chikhi A; Bensegueni A; Boulahrouf A; Bencharif M
    In Silico Biol; 2006; 6(5):459-66. PubMed ID: 17274774
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical characterization of MurF from Streptococcus pneumoniae and the identification of a new MurF inhibitor through ligand-based virtual screening.
    Turk S; Hrast M; Sosic I; Barreteau H; Mengin-Lecreulx D; Blanot D; Gobec S
    Acta Chim Slov; 2013; 60(2):294-9. PubMed ID: 23878932
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.