BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

341 related articles for article (PubMed ID: 21502318)

  • 1. The beta-arrestin pathway-selective type 1A angiotensin receptor (AT1A) agonist [Sar1,Ile4,Ile8]angiotensin II regulates a robust G protein-independent signaling network.
    Kendall RT; Strungs EG; Rachidi SM; Lee MH; El-Shewy HM; Luttrell DK; Janech MG; Luttrell LM
    J Biol Chem; 2011 Jun; 286(22):19880-91. PubMed ID: 21502318
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2.
    Wei H; Ahn S; Barnes WG; Lefkowitz RJ
    J Biol Chem; 2004 Nov; 279(46):48255-61. PubMed ID: 15355986
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers.
    Wilson PC; Lee MH; Appleton KM; El-Shewy HM; Morinelli TA; Peterson YK; Luttrell LM; Jaffa AA
    J Biol Chem; 2013 Jun; 288(26):18872-84. PubMed ID: 23661707
    [TBL] [Abstract][Full Text] [Related]  

  • 4. β-Arrestin-biased AT1R stimulation promotes extracellular matrix synthesis in renal fibrosis.
    Wang Y; Huang J; Liu X; Niu Y; Zhao L; Yu Y; Zhou L; Lu L; Yu C
    Am J Physiol Renal Physiol; 2017 Jul; 313(1):F1-F8. PubMed ID: 28274926
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ezrin, radixin, and moesin phosphorylation in NIH3T3 cells revealed angiotensin II type 1 receptor cell-type-dependent biased signaling.
    Ibrahim IA; Nakaya M; Kurose H
    J Pharmacol Sci; 2013; 122(1):1-9. PubMed ID: 23575451
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).
    Xiao K; Sun J; Kim J; Rajagopal S; Zhai B; Villén J; Haas W; Kovacs JJ; Shukla AK; Hara MR; Hernandez M; Lachmann A; Zhao S; Lin Y; Cheng Y; Mizuno K; Ma'ayan A; Gygi SP; Lefkowitz RJ
    Proc Natl Acad Sci U S A; 2010 Aug; 107(34):15299-304. PubMed ID: 20686112
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs.
    Zimmerman B; Beautrait A; Aguila B; Charles R; Escher E; Claing A; Bouvier M; Laporte SA
    Sci Signal; 2012 Apr; 5(221):ra33. PubMed ID: 22534132
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of beta-arrestin-mediated desensitization and signaling in the control of angiotensin AT1a receptor-stimulated transcription.
    Lee MH; El-Shewy HM; Luttrell DK; Luttrell LM
    J Biol Chem; 2008 Jan; 283(4):2088-97. PubMed ID: 18006496
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Arrestin-dependent angiotensin AT1 receptor signaling regulates Akt and mTor-mediated protein synthesis.
    Kendall RT; Lee MH; Pleasant DL; Robinson K; Kuppuswamy D; McDermott PJ; Luttrell LM
    J Biol Chem; 2014 Sep; 289(38):26155-26166. PubMed ID: 25081544
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Association of beta-Arrestin 1 with the type 1A angiotensin II receptor involves phosphorylation of the receptor carboxyl terminus and correlates with receptor internalization.
    Qian H; Pipolo L; Thomas WG
    Mol Endocrinol; 2001 Oct; 15(10):1706-19. PubMed ID: 11579203
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selectively engaging β-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance.
    Violin JD; DeWire SM; Yamashita D; Rominger DH; Nguyen L; Schiller K; Whalen EJ; Gowen M; Lark MW
    J Pharmacol Exp Ther; 2010 Dec; 335(3):572-9. PubMed ID: 20801892
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Loss of biased signaling at a G protein-coupled receptor in overexpressed systems.
    Li A; Liu S; Huang R; Ahn S; Lefkowitz RJ
    PLoS One; 2023; 18(3):e0283477. PubMed ID: 36961836
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Angiotensin II type 1 receptor variants alter endosomal receptor-β-arrestin complex stability and MAPK activation.
    Cao Y; Kumar S; Namkung Y; Gagnon L; Cho A; Laporte SA
    J Biol Chem; 2020 Sep; 295(38):13169-13180. PubMed ID: 32703898
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor.
    Kim J; Ahn S; Rajagopal K; Lefkowitz RJ
    J Biol Chem; 2009 May; 284(18):11953-62. PubMed ID: 19254952
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biased signaling of the angiotensin II type 1 receptor can be mediated through distinct mechanisms.
    Bonde MM; Hansen JT; Sanni SJ; Haunsø S; Gammeltoft S; Lyngsø C; Hansen JL
    PLoS One; 2010 Nov; 5(11):e14135. PubMed ID: 21152433
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation.
    Gesty-Palmer D; Chen M; Reiter E; Ahn S; Nelson CD; Wang S; Eckhardt AE; Cowan CL; Spurney RF; Luttrell LM; Lefkowitz RJ
    J Biol Chem; 2006 Apr; 281(16):10856-64. PubMed ID: 16492667
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.
    Wei H; Ahn S; Shenoy SK; Karnik SS; Hunyady L; Luttrell LM; Lefkowitz RJ
    Proc Natl Acad Sci U S A; 2003 Sep; 100(19):10782-7. PubMed ID: 12949261
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Angiotensin II activates NF-κB through AT1A receptor recruitment of β-arrestin in cultured rat vascular smooth muscle cells.
    Morinelli TA; Lee MH; Kendall RT; Luttrell LM; Walker LP; Ullian ME
    Am J Physiol Cell Physiol; 2013 Jun; 304(12):C1176-86. PubMed ID: 23576578
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential beta-arrestin binding of AT1 and AT2 angiotensin receptors.
    Turu G; Szidonya L; Gáborik Z; Buday L; Spät A; Clark AJ; Hunyady L
    FEBS Lett; 2006 Jan; 580(1):41-5. PubMed ID: 16359671
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes.
    Rajagopal K; Whalen EJ; Violin JD; Stiber JA; Rosenberg PB; Premont RT; Coffman TM; Rockman HA; Lefkowitz RJ
    Proc Natl Acad Sci U S A; 2006 Oct; 103(44):16284-9. PubMed ID: 17060617
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.