These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 21502511)

  • 1. Aprataxin localizes to mitochondria and preserves mitochondrial function.
    Sykora P; Croteau DL; Bohr VA; Wilson DM
    Proc Natl Acad Sci U S A; 2011 May; 108(18):7437-42. PubMed ID: 21502511
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates.
    Ahel I; Rass U; El-Khamisy SF; Katyal S; Clements PM; McKinnon PJ; Caldecott KW; West SC
    Nature; 2006 Oct; 443(7112):713-6. PubMed ID: 16964241
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Actions of aprataxin in multiple DNA repair pathways.
    Rass U; Ahel I; West SC
    J Biol Chem; 2007 Mar; 282(13):9469-9474. PubMed ID: 17276982
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aprataxin forms a discrete branch in the HIT (histidine triad) superfamily of proteins with both DNA/RNA binding and nucleotide hydrolase activities.
    Kijas AW; Harris JL; Harris JM; Lavin MF
    J Biol Chem; 2006 May; 281(20):13939-48. PubMed ID: 16547001
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aprataxin, a novel protein that protects against genotoxic stress.
    Gueven N; Becherel OJ; Kijas AW; Chen P; Howe O; Rudolph JH; Gatti R; Date H; Onodera O; Taucher-Scholz G; Lavin MF
    Hum Mol Genet; 2004 May; 13(10):1081-93. PubMed ID: 15044383
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lack of aprataxin impairs mitochondrial functions via downregulation of the APE1/NRF1/NRF2 pathway.
    Garcia-Diaz B; Barca E; Balreira A; Lopez LC; Tadesse S; Krishna S; Naini A; Mariotti C; Castellotti B; Quinzii CM
    Hum Mol Genet; 2015 Aug; 24(16):4516-29. PubMed ID: 25976310
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Disease-associated mutations inactivate AMP-lysine hydrolase activity of Aprataxin.
    Seidle HF; Bieganowski P; Brenner C
    J Biol Chem; 2005 Jun; 280(22):20927-31. PubMed ID: 15790557
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.
    Sano Y; Date H; Igarashi S; Onodera O; Oyake M; Takahashi T; Hayashi S; Morimatsu M; Takahashi H; Makifuchi T; Fukuhara N; Tsuji S
    Ann Neurol; 2004 Feb; 55(2):241-9. PubMed ID: 14755728
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular mechanism of DNA deadenylation by the neurological disease protein aprataxin.
    Rass U; Ahel I; West SC
    J Biol Chem; 2008 Dec; 283(49):33994-4001. PubMed ID: 18836178
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin.
    Moreira MC; Barbot C; Tachi N; Kozuka N; Uchida E; Gibson T; Mendonça P; Costa M; Barros J; Yanagisawa T; Watanabe M; Ikeda Y; Aoki M; Nagata T; Coutinho P; Sequeiros J; Koenig M
    Nat Genet; 2001 Oct; 29(2):189-93. PubMed ID: 11586300
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA single-strand break repair is impaired in aprataxin-related ataxia.
    Hirano M; Yamamoto A; Mori T; Lan L; Iwamoto TA; Aoki M; Shimada K; Furiya Y; Kariya S; Asai H; Yasui A; Nishiwaki T; Imoto K; Kobayashi N; Kiriyama T; Nagata T; Konishi N; Itoyama Y; Ueno S
    Ann Neurol; 2007 Feb; 61(2):162-74. PubMed ID: 17315206
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin.
    El-Khamisy SF; Katyal S; Patel P; Ju L; McKinnon PJ; Caldecott KW
    DNA Repair (Amst); 2009 Jun; 8(6):760-6. PubMed ID: 19303373
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of TDP1 and APTX in mitochondrial DNA repair.
    Meagher M; Lightowlers RN
    Biochimie; 2014 May; 100():121-4. PubMed ID: 24161509
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment.
    Dopeso H; Mateo-Lozano S; Elez E; Landolfi S; Ramos Pascual FJ; Hernández-Losa J; Mazzolini R; Rodrigues P; Bazzocco S; Carreras MJ; Espín E; Armengol M; Wilson AJ; Mariadason JM; Ramon Y Cajal S; Tabernero J; Schwartz S; Arango D
    Clin Cancer Res; 2010 Apr; 16(8):2375-82. PubMed ID: 20371676
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular underpinnings of Aprataxin RNA/DNA deadenylase function and dysfunction in neurological disease.
    Schellenberg MJ; Tumbale PP; Williams RS
    Prog Biophys Mol Biol; 2015 Mar; 117(2-3):157-165. PubMed ID: 25637650
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Slow mitochondrial repair of 5'-AMP renders mtDNA susceptible to damage in APTX deficient cells.
    Akbari M; Sykora P; Bohr VA
    Sci Rep; 2015 Aug; 5():12876. PubMed ID: 26256098
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Generation and characterization of induced pluripotent stem cell (iPSC) line (JUCTCi002-A) from a patient with ataxia with oculomotor apraxia type 1 (AOA1) harboring a homozygous mutation in the APTX gene.
    Ababneh NA; Al-Kurdi B; Ali D; Abuarqoub D; Barham R; Alzibdeh AM; Khanfar AN; Altantawi AM; Ryalat AT; Sharrack B; Awidi A
    Stem Cell Res; 2020 Oct; 48():101925. PubMed ID: 32769066
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells.
    Zheng J; Croteau DL; Bohr VA; Akbari M
    Nucleic Acids Res; 2019 May; 47(8):4086-4110. PubMed ID: 30986824
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure of an aprataxin-DNA complex with insights into AOA1 neurodegenerative disease.
    Tumbale P; Appel CD; Kraehenbuehl R; Robertson PD; Williams JS; Krahn J; Ahel I; Williams RS
    Nat Struct Mol Biol; 2011 Oct; 18(11):1189-95. PubMed ID: 21984210
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends.
    Takahashi T; Tada M; Igarashi S; Koyama A; Date H; Yokoseki A; Shiga A; Yoshida Y; Tsuji S; Nishizawa M; Onodera O
    Nucleic Acids Res; 2007; 35(11):3797-809. PubMed ID: 17519253
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.