353 related articles for article (PubMed ID: 21504625)
41. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers.
Cheng M; Quail MR; Gingrich DE; Ott GR; Lu L; Wan W; Albom MS; Angeles TS; Aimone LD; Cristofani F; Machiorlatti R; Abele C; Ator MA; Dorsey BD; Inghirami G; Ruggeri BA
Mol Cancer Ther; 2012 Mar; 11(3):670-9. PubMed ID: 22203728
[TBL] [Abstract][Full Text] [Related]
42. [Cancer therapy by PARP inhibitors].
Seimiya H
Nihon Rinsho; 2015 Aug; 73(8):1330-5. PubMed ID: 26281686
[TBL] [Abstract][Full Text] [Related]
43. PARP inhibitors for cancer therapy.
Curtin NJ
Expert Rev Mol Med; 2005 Mar; 7(4):1-20. PubMed ID: 15836799
[TBL] [Abstract][Full Text] [Related]
44. Activity of EGFR-tyrosine kinase and ALK inhibitors for EML4-ALK-rearranged non-small-cell lung cancer harbored coexisting EGFR mutation.
Miyanaga A; Shimizu K; Noro R; Seike M; Kitamura K; Kosaihira S; Minegishi Y; Shukuya T; Yoshimura A; Kawamoto M; Tsuchiya S; Hagiwara K; Soda M; Takeuchi K; Yamamoto N; Mano H; Ishikawa Y; Gemma A
BMC Cancer; 2013 May; 13():262. PubMed ID: 23714228
[TBL] [Abstract][Full Text] [Related]
45. Evaluation of EML4-ALK fusion proteins in non-small cell lung cancer using small molecule inhibitors.
Li Y; Ye X; Liu J; Zha J; Pei L
Neoplasia; 2011 Jan; 13(1):1-11. PubMed ID: 21245935
[TBL] [Abstract][Full Text] [Related]
46. Poly(ADP-Ribose) polymerase inhibition: "targeted" therapy for triple-negative breast cancer.
Anders CK; Winer EP; Ford JM; Dent R; Silver DP; Sledge GW; Carey LA
Clin Cancer Res; 2010 Oct; 16(19):4702-10. PubMed ID: 20858840
[TBL] [Abstract][Full Text] [Related]
47. The anaplastic lymphoma kinase as an oncogene in solid tumors.
Voena C; Peola S; Chiarle R
Front Biosci (Schol Ed); 2015 Jun; 7(2):269-82. PubMed ID: 25961702
[TBL] [Abstract][Full Text] [Related]
48. Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants.
Heuckmann JM; Balke-Want H; Malchers F; Peifer M; Sos ML; Koker M; Meder L; Lovly CM; Heukamp LC; Pao W; Küppers R; Thomas RK
Clin Cancer Res; 2012 Sep; 18(17):4682-90. PubMed ID: 22912387
[TBL] [Abstract][Full Text] [Related]
49. Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics.
He JX; Yang CH; Miao ZH
Acta Pharmacol Sin; 2010 Sep; 31(9):1172-80. PubMed ID: 20676117
[TBL] [Abstract][Full Text] [Related]
50. The preclinical profile of crizotinib for the treatment of non-small-cell lung cancer and other neoplastic disorders.
Roskoski R
Expert Opin Drug Discov; 2013 Sep; 8(9):1165-79. PubMed ID: 23805942
[TBL] [Abstract][Full Text] [Related]
51. Current Strategies to Overcome Resistance to ALK-Inhibitor Agents.
Simionato F; Frizziero M; Carbone C; Tortora G; Melisi D
Curr Drug Metab; 2015; 16(7):585-96. PubMed ID: 26264346
[TBL] [Abstract][Full Text] [Related]
52. The ALK gene, an attractive target for inhibitor development.
Tartari CJ; Scapozza L; Gambacorti-Passerini C
Curr Top Med Chem; 2011; 11(11):1406-19. PubMed ID: 21513493
[TBL] [Abstract][Full Text] [Related]
53. A major component of vitamin E, α-tocopherol inhibits the anti-tumor activity of crizotinib against cells transformed by EML4-ALK.
Uchihara Y; Kidokoro T; Tago K; Mashino T; Tamura H; Funakoshi-Tago M
Eur J Pharmacol; 2018 Apr; 825():1-9. PubMed ID: 29444468
[TBL] [Abstract][Full Text] [Related]
54. Resistance to Crizotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) with ALK Rearrangement: Mechanisms, Treatment Strategies and New Targeted Therapies.
Casaluce F; Sgambato A; Sacco PC; Palazzolo G; Maione P; Rossi A; Ciardiello F; Gridelli C
Curr Clin Pharmacol; 2016; 11(2):77-87. PubMed ID: 27138017
[TBL] [Abstract][Full Text] [Related]
55. Differential protein stability and clinical responses of EML4-ALK fusion variants to various ALK inhibitors in advanced ALK-rearranged non-small cell lung cancer.
Woo CG; Seo S; Kim SW; Jang SJ; Park KS; Song JY; Lee B; Richards MW; Bayliss R; Lee DH; Choi J
Ann Oncol; 2017 Apr; 28(4):791-797. PubMed ID: 28039177
[TBL] [Abstract][Full Text] [Related]
56. Molecular breakdown: a comprehensive view of anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer.
Noh KW; Lee MS; Lee SE; Song JY; Shin HT; Kim YJ; Oh DY; Jung K; Sung M; Kim M; An S; Han J; Shim YM; Zo JI; Kim J; Park WY; Lee SH; Choi YL
J Pathol; 2017 Nov; 243(3):307-319. PubMed ID: 28741662
[TBL] [Abstract][Full Text] [Related]
57. ALK-immunoreactive neoplasms.
Minoo P; Wang HY
Int J Clin Exp Pathol; 2012; 5(5):397-410. PubMed ID: 22808292
[TBL] [Abstract][Full Text] [Related]
58. Mdm2 and MdmX inhibitors for the treatment of cancer: a patent review (2011-present).
Zak K; Pecak A; Rys B; Wladyka B; Dömling A; Weber L; Holak TA; Dubin G
Expert Opin Ther Pat; 2013 Apr; 23(4):425-48. PubMed ID: 23374098
[TBL] [Abstract][Full Text] [Related]
59. Activity of second-generation ALK inhibitors against crizotinib-resistant mutants in an NPM-ALK model compared to EML4-ALK.
Fontana D; Ceccon M; Gambacorti-Passerini C; Mologni L
Cancer Med; 2015 Jul; 4(7):953-65. PubMed ID: 25727400
[TBL] [Abstract][Full Text] [Related]
60. Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor.
Menichincheri M; Ardini E; Magnaghi P; Avanzi N; Banfi P; Bossi R; Buffa L; Canevari G; Ceriani L; Colombo M; Corti L; Donati D; Fasolini M; Felder E; Fiorelli C; Fiorentini F; Galvani A; Isacchi A; Borgia AL; Marchionni C; Nesi M; Orrenius C; Panzeri A; Pesenti E; Rusconi L; Saccardo MB; Vanotti E; Perrone E; Orsini P
J Med Chem; 2016 Apr; 59(7):3392-408. PubMed ID: 27003761
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]