323 related articles for article (PubMed ID: 21506277)
1. Inhibitors of the interactions between HIV-1 IN and the cofactor LEDGF/p75.
De Luca L; Ferro S; Morreale F; De Grazia S; Chimirri A
ChemMedChem; 2011 Jul; 6(7):1184-91. PubMed ID: 21506277
[TBL] [Abstract][Full Text] [Related]
2. D77, one benzoic acid derivative, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75.
Du L; Zhao Y; Chen J; Yang L; Zheng Y; Tang Y; Shen X; Jiang H
Biochem Biophys Res Commun; 2008 Oct; 375(1):139-44. PubMed ID: 18691555
[TBL] [Abstract][Full Text] [Related]
3. Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75.
De Luca L; Barreca ML; Ferro S; Christ F; Iraci N; Gitto R; Monforte AM; Debyser Z; Chimirri A
ChemMedChem; 2009 Aug; 4(8):1311-6. PubMed ID: 19565598
[TBL] [Abstract][Full Text] [Related]
4. The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy.
Christ F; Debyser Z
Virology; 2013 Jan; 435(1):102-9. PubMed ID: 23217620
[TBL] [Abstract][Full Text] [Related]
5. Identification of the LEDGF/p75 binding site in HIV-1 integrase.
Busschots K; Voet A; De Maeyer M; Rain JC; Emiliani S; Benarous R; Desender L; Debyser Z; Christ F
J Mol Biol; 2007 Feb; 365(5):1480-92. PubMed ID: 17137594
[TBL] [Abstract][Full Text] [Related]
6. Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor.
De Luca L; Ferro S; Gitto R; Barreca ML; Agnello S; Christ F; Debyser Z; Chimirri A
Bioorg Med Chem; 2010 Nov; 18(21):7515-21. PubMed ID: 20850978
[TBL] [Abstract][Full Text] [Related]
7. Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: insight into integrase-DNA complex formation and catalysis.
Al-Mawsawi LQ; Christ F; Dayam R; Debyser Z; Neamati N
FEBS Lett; 2008 Apr; 582(10):1425-30. PubMed ID: 18331842
[TBL] [Abstract][Full Text] [Related]
8. Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75.
Bartholomeeusen K; De Rijck J; Busschots K; Desender L; Gijsbers R; Emiliani S; Benarous R; Debyser Z; Christ F
J Mol Biol; 2007 Sep; 372(2):407-21. PubMed ID: 17669426
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of the interaction between HIV-1 integrase and its cofactor LEDGF/p75: a promising approach in anti-retroviral therapy.
De Luca L; Ferro S; Morreale F; Chimirri A
Mini Rev Med Chem; 2011 Jul; 11(8):714-27. PubMed ID: 21651465
[TBL] [Abstract][Full Text] [Related]
10. Insights into the interactions between HIV-1 integrase and human LEDGF/p75 by molecular dynamics simulation and free energy calculation.
Zhao Y; Li W; Zeng J; Liu G; Tang Y
Proteins; 2008 Aug; 72(2):635-45. PubMed ID: 18247352
[TBL] [Abstract][Full Text] [Related]
11. Computational studies of the interaction between the HIV-1 integrase tetramer and the cofactor LEDGF/p75: insights from molecular dynamics simulations and the informational spectrum method.
Tintori C; Veljkovic N; Veljkovic V; Botta M
Proteins; 2010 Dec; 78(16):3396-408. PubMed ID: 20878714
[TBL] [Abstract][Full Text] [Related]
12. Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering.
Vanegas M; Llano M; Delgado S; Thompson D; Peretz M; Poeschla E
J Cell Sci; 2005 Apr; 118(Pt 8):1733-43. PubMed ID: 15797927
[TBL] [Abstract][Full Text] [Related]
13. [LEDGF/p75: a novel target for anti-HIV therapy and advances in the study of its related inhibitors].
Chen WM; Liu XY
Yao Xue Xue Bao; 2009 Sep; 44(9):953-60. PubMed ID: 20055168
[TBL] [Abstract][Full Text] [Related]
14. Cyclic peptide inhibitors of HIV-1 integrase derived from the LEDGF/p75 protein.
Hayouka Z; Hurevich M; Levin A; Benyamini H; Iosub A; Maes M; Shalev DE; Loyter A; Gilon C; Friedler A
Bioorg Med Chem; 2010 Dec; 18(23):8388-95. PubMed ID: 20974536
[TBL] [Abstract][Full Text] [Related]
15. In vitro DNA tethering of HIV-1 integrase by the transcriptional coactivator LEDGF/p75.
McNeely M; Hendrix J; Busschots K; Boons E; Deleersnijder A; Gerard M; Christ F; Debyser Z
J Mol Biol; 2011 Jul; 410(5):811-30. PubMed ID: 21763490
[TBL] [Abstract][Full Text] [Related]
16. The evaluation of statins as potential inhibitors of the LEDGF/p75-HIV-1 integrase interaction.
Harrison AT; Kriel FH; Papathanasopoulos MA; Mosebi S; Abrahams S; Hewer R
Chem Biol Drug Des; 2015 Mar; 85(3):290-5. PubMed ID: 24954548
[TBL] [Abstract][Full Text] [Related]
17. Screening for antiviral inhibitors of the HIV integrase-LEDGF/p75 interaction using the AlphaScreen luminescent proximity assay.
Hou Y; McGuinness DE; Prongay AJ; Feld B; Ingravallo P; Ogert RA; Lunn CA; Howe JA
J Biomol Screen; 2008 Jun; 13(5):406-14. PubMed ID: 18480474
[TBL] [Abstract][Full Text] [Related]
18. 1,4-Bis(5-(naphthalen-1-yl)thiophen-2-yl)naphthalene, a small molecule, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular Lens epithelium-derived growth factor.
Gu WG; Ip DT; Liu SJ; Chan JH; Wang Y; Zhang X; Zheng YT; Wan DC
Chem Biol Interact; 2014 Apr; 213():21-7. PubMed ID: 24480521
[TBL] [Abstract][Full Text] [Related]
19. Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.
Hombrouck A; De Rijck J; Hendrix J; Vandekerckhove L; Voet A; De Maeyer M; Witvrouw M; Engelborghs Y; Christ F; Gijsbers R; Debyser Z
PLoS Pathog; 2007 Mar; 3(3):e47. PubMed ID: 17397262
[TBL] [Abstract][Full Text] [Related]
20. Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75.
Llano M; Vanegas M; Hutchins N; Thompson D; Delgado S; Poeschla EM
J Mol Biol; 2006 Jul; 360(4):760-73. PubMed ID: 16793062
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
