220 related articles for article (PubMed ID: 21507633)
21. Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors.
Zhao H; Liu G; Xin Z; Serby MD; Pei Z; Szczepankiewicz BG; Hajduk PJ; Abad-Zapatero C; Hutchins CW; Lubben TH; Ballaron SJ; Haasch DL; Kaszubska W; Rondinone CM; Trevillyan JM; Jirousek MR
Bioorg Med Chem Lett; 2004 Nov; 14(22):5543-6. PubMed ID: 15482920
[TBL] [Abstract][Full Text] [Related]
22. Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase.
Holder S; Lilly M; Brown ML
Bioorg Med Chem; 2007 Oct; 15(19):6463-73. PubMed ID: 17637507
[TBL] [Abstract][Full Text] [Related]
23. Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity.
Pogacic V; Bullock AN; Fedorov O; Filippakopoulos P; Gasser C; Biondi A; Meyer-Monard S; Knapp S; Schwaller J
Cancer Res; 2007 Jul; 67(14):6916-24. PubMed ID: 17638903
[TBL] [Abstract][Full Text] [Related]
24. Novel potent dual inhibitors of CK2 and Pim kinases with antiproliferative activity against cancer cells.
Pierre F; Regan CF; Chevrel MC; Siddiqui-Jain A; Macalino D; Streiner N; Drygin D; Haddach M; O'Brien SE; Rice WG; Ryckman DM
Bioorg Med Chem Lett; 2012 May; 22(9):3327-31. PubMed ID: 22460033
[TBL] [Abstract][Full Text] [Related]
25. Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode.
Qian K; Wang L; Cywin CL; Farmer BT; Hickey E; Homon C; Jakes S; Kashem MA; Lee G; Leonard S; Li J; Magboo R; Mao W; Pack E; Peng C; Prokopowicz A; Welzel M; Wolak J; Morwick T
J Med Chem; 2009 Apr; 52(7):1814-27. PubMed ID: 19256503
[TBL] [Abstract][Full Text] [Related]
26. Discovery and optimization of pyrrolo[1,2-a]pyrazinones leads to novel and selective inhibitors of PIM kinases.
Casuscelli F; Ardini E; Avanzi N; Casale E; Cervi G; D'Anello M; Donati D; Faiardi D; Ferguson RD; Fogliatto G; Galvani A; Marsiglio A; Mirizzi DG; Montemartini M; Orrenius C; Papeo G; Piutti C; Salom B; Felder ER
Bioorg Med Chem; 2013 Dec; 21(23):7364-80. PubMed ID: 24139169
[TBL] [Abstract][Full Text] [Related]
27. 3-Amino-pyrazolo[3,4-d]pyrimidines as p38α kinase inhibitors: design and development to a highly selective lead.
Soth M; Abbot S; Abubakari A; Arora N; Arzeno H; Billedeau R; Dewdney N; Durkin K; Frauchiger S; Ghate M; Goldstein DM; Hill RJ; Kuglstatter A; Li F; Loe B; McCaleb K; McIntosh J; Papp E; Park J; Stahl M; Sung ML; Suttman R; Swinney DC; Weller P; Wong B; Zecic H; Gabriel T
Bioorg Med Chem Lett; 2011 Jun; 21(11):3452-6. PubMed ID: 21515047
[TBL] [Abstract][Full Text] [Related]
28. Non-oxime pyrazole based inhibitors of B-Raf kinase.
Newhouse BJ; Hansen JD; Grina J; Welch M; Topalov G; Littman N; Callejo M; Martinson M; Galbraith S; Laird ER; Brandhuber BJ; Vigers G; Morales T; Woessner R; Randolph N; Lyssikatos J; Olivero A
Bioorg Med Chem Lett; 2011 Jun; 21(11):3488-92. PubMed ID: 21536432
[TBL] [Abstract][Full Text] [Related]
29. Discovery of novel quinoline carboxylic acid series as DGAT1 inhibitors.
Zhou G; Ting PC; Wishart G; Zorn N; Aslanian RG; Lin M; Smith M; Walker SS; Cook J; Van Heek M; Lachowicz J
Bioorg Med Chem Lett; 2014 Apr; 24(7):1790-4. PubMed ID: 24618302
[TBL] [Abstract][Full Text] [Related]
30. The design, synthesis, and biological evaluation of PIM kinase inhibitors.
Tsuhako AL; Brown DS; Koltun ES; Aay N; Arcalas A; Chan V; Du H; Engst S; Franzini M; Galan A; Huang P; Johnston S; Kane B; Kim MH; Laird AD; Lin R; Mock L; Ngan I; Pack M; Stott G; Stout TJ; Yu P; Zaharia C; Zhang W; Zhou P; Nuss JM; Kearney PC; Xu W
Bioorg Med Chem Lett; 2012 Jun; 22(11):3732-8. PubMed ID: 22542012
[TBL] [Abstract][Full Text] [Related]
31. Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1).
Asano Y; Kitamura S; Ohra T; Aso K; Igata H; Tamura T; Kawamoto T; Tanaka T; Sogabe S; Matsumoto S; Yamaguchi M; Kimura H; Itoh F
Bioorg Med Chem; 2008 Apr; 16(8):4715-32. PubMed ID: 18313304
[TBL] [Abstract][Full Text] [Related]
32. Synthesis and SAR of alpha-sulfonylcarboxylic acids as potent matrix metalloproteinase inhibitors.
Zhang YM; Fan X; Xiang B; Chakravarty D; Scannevin R; Burke S; Karnachi P; Rhodes K; Jackson P
Bioorg Med Chem Lett; 2006 Jun; 16(12):3096-100. PubMed ID: 16632358
[TBL] [Abstract][Full Text] [Related]
33. Synthesis and bioevaluation of 2-phenyl-4-methyl-1,3-selenazole-5-carboxylic acids as potent xanthine oxidase inhibitors.
Guan Q; Cheng Z; Ma X; Wang L; Feng D; Cui Y; Bao K; Wu L; Zhang W
Eur J Med Chem; 2014 Oct; 85():508-16. PubMed ID: 25113879
[TBL] [Abstract][Full Text] [Related]
34. Identification of pyrrolo[2,3-g]indazoles as new Pim kinase inhibitors.
Gavara L; Suchaud V; Nauton L; Théry V; Anizon F; Moreau P
Bioorg Med Chem Lett; 2013 Apr; 23(8):2298-301. PubMed ID: 23499503
[TBL] [Abstract][Full Text] [Related]
35. Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery.
Erlanson DA; Arndt JW; Cancilla MT; Cao K; Elling RA; English N; Friedman J; Hansen SK; Hession C; Joseph I; Kumaravel G; Lee WC; Lind KE; McDowell RS; Miatkowski K; Nguyen C; Nguyen TB; Park S; Pathan N; Penny DM; Romanowski MJ; Scott D; Silvian L; Simmons RL; Tangonan BT; Yang W; Sun L
Bioorg Med Chem Lett; 2011 May; 21(10):3078-83. PubMed ID: 21459573
[TBL] [Abstract][Full Text] [Related]
36. Discovery of N-substituted 7-azaindoles as Pan-PIM kinase inhibitors - Lead series identification - Part II.
Barberis C; Moorcroft N; Pribish J; Tserlin E; Gross A; Czekaj M; Barrague M; Erdman P; Majid T; Batchelor J; Levit M; Hebert A; Shen L; Moreno-Mazza S; Wang A
Bioorg Med Chem Lett; 2017 Oct; 27(20):4735-4740. PubMed ID: 28927793
[TBL] [Abstract][Full Text] [Related]
37. Identification and structure-activity relationship of 8-hydroxy-quinoline-7-carboxylic acid derivatives as inhibitors of Pim-1 kinase.
Sliman F; Blairvacq M; Durieu E; Meijer L; Rodrigo J; Desmaële D
Bioorg Med Chem Lett; 2010 May; 20(9):2801-5. PubMed ID: 20363627
[TBL] [Abstract][Full Text] [Related]
38. Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.
Bora-Tatar G; Dayangaç-Erden D; Demir AS; Dalkara S; Yelekçi K; Erdem-Yurter H
Bioorg Med Chem; 2009 Jul; 17(14):5219-28. PubMed ID: 19520580
[TBL] [Abstract][Full Text] [Related]
39. Discovery of novel pyrazolo[1,5-a]pyrimidines as potent pan-Pim inhibitors by structure- and property-based drug design.
Wang X; Magnuson S; Pastor R; Fan E; Hu H; Tsui V; Deng W; Murray J; Steffek M; Wallweber H; Moffat J; Drummond J; Chan G; Harstad E; Ebens AJ
Bioorg Med Chem Lett; 2013 Jun; 23(11):3149-53. PubMed ID: 23623490
[TBL] [Abstract][Full Text] [Related]
40. Synthesis and evaluation of benzothiazole-based analogues as novel, potent, and selective fatty acid amide hydrolase inhibitors.
Wang X; Sarris K; Kage K; Zhang D; Brown SP; Kolasa T; Surowy C; El Kouhen OF; Muchmore SW; Brioni JD; Stewart AO
J Med Chem; 2009 Jan; 52(1):170-80. PubMed ID: 19072118
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
