These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
437 related articles for article (PubMed ID: 21509569)
1. Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma. Faganel Kotnik B; Grabnar I; Bohanec Grabar P; Dolžan V; Jazbec J Eur J Clin Pharmacol; 2011 Oct; 67(10):993-1006. PubMed ID: 21509569 [TBL] [Abstract][Full Text] [Related]
2. Influence of folate pathway polymorphisms on high-dose methotrexate-related toxicity and survival in childhood acute lymphoblastic leukemia. Erčulj N; Kotnik BF; Debeljak M; Jazbec J; Dolžan V Leuk Lymphoma; 2012 Jun; 53(6):1096-104. PubMed ID: 22074251 [TBL] [Abstract][Full Text] [Related]
3. Effects of gene polymorphisms on delayed MTX clearance, toxicity, and metabolomic changes after HD-MTX treatment in children with acute lymphoblastic leukemia. Zhou Y; He H; Ding L; Wang T; Liu X; Zhang M; Zhang A; Fu J Eur J Pediatr; 2024 Feb; 183(2):581-590. PubMed ID: 37851084 [TBL] [Abstract][Full Text] [Related]
4. Use of MTHFR C677T polymorphism and plasma pharmacokinetics to predict methotrexate toxicity in patients with acute lymphoblastic leukemia. Mahmoud LB; Mdhaffar M; Frikha R; Ghozzi H; Hakim A; Sahnoun Z; Elloumi M; Zeghal K Adv Clin Exp Med; 2018 Aug; 27(8):1061-1068. PubMed ID: 29911750 [TBL] [Abstract][Full Text] [Related]
5. Folate pathway genetic polymorphisms modulate methotrexate-induced toxicity in childhood acute lymphoblastic leukemia. Yousef AM; Farhad R; Alshamaseen D; Alsheikh A; Zawiah M; Kadi T Cancer Chemother Pharmacol; 2019 Apr; 83(4):755-762. PubMed ID: 30684021 [TBL] [Abstract][Full Text] [Related]
6. Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia. de Jonge R; Hooijberg JH; van Zelst BD; Jansen G; van Zantwijk CH; Kaspers GJ; Peters GJ; Ravindranath Y; Pieters R; Lindemans J Blood; 2005 Jul; 106(2):717-20. PubMed ID: 15797993 [TBL] [Abstract][Full Text] [Related]
7. Associations of novel genetic variations in the folate-related and ARID5B genes with the pharmacokinetics and toxicity of high-dose methotrexate in paediatric acute lymphoblastic leukaemia. Csordas K; Lautner-Csorba O; Semsei AF; Harnos A; Hegyi M; Erdelyi DJ; Eipel OT; Szalai C; Kovacs GT Br J Haematol; 2014 Aug; 166(3):410-20. PubMed ID: 24712521 [TBL] [Abstract][Full Text] [Related]
8. Genetic polymorphisms in candidate genes predict increased toxicity with methotrexate therapy in Lebanese children with acute lymphoblastic leukemia. Zgheib NK; Akra-Ismail M; Aridi C; Mahfouz R; Abboud MR; Solh H; Muwakkit SA Pharmacogenet Genomics; 2014 Aug; 24(8):387-96. PubMed ID: 25007187 [TBL] [Abstract][Full Text] [Related]
9. Influence of plasma methotrexate level and MTHFR genotype in Korean paediatric patients with acute lymphoblastic leukaemia. Chae H; Kim M; Choi SH; Kim SK; Lee JW; Chung NG; Cho B; Kim Y J Chemother; 2020 Sep; 32(5):251-259. PubMed ID: 32431230 [TBL] [Abstract][Full Text] [Related]
10. Effect of polymorphisms within methotrexate pathway genes on methotrexate toxicity and plasma levels in adults with hematological malignancies. Suthandiram S; Gan GG; Zain SM; Bee PC; Lian LH; Chang KM; Ong TC; Mohamed Z Pharmacogenomics; 2014 Aug; 15(11):1479-94. PubMed ID: 25303299 [TBL] [Abstract][Full Text] [Related]
11. Association of MTHFR and ABCB1 polymorphisms with MTX-induced mucositis in Chinese paediatric patients with acute lymphoblastic leukaemia, lymphoma or osteosarcoma-A retrospective cohort study. Gong Y; Luo L; Wang L; Chen J; Chen F; Ma Y; Xu Z; Sun Y; Luo L; Shi C; Li X J Clin Pharm Ther; 2021 Dec; 46(6):1557-1563. PubMed ID: 34346513 [TBL] [Abstract][Full Text] [Related]
12. Influence of Folate-Related Gene Polymorphisms on High-Dose Methotrexate-Related Toxicity and Prognosis in Turkish Children with Acute Lymphoblastic Leukemia. Yazıcıoğlu B; Kaya Z; Güntekin Ergun S; Perçin F; Koçak Ü; Yenicesu İ; Gürsel T Turk J Haematol; 2017 Jun; 34(2):143-150. PubMed ID: 27094381 [TBL] [Abstract][Full Text] [Related]
13. Methotrexate-induced mucositis in acute leukemia patients is not associated with the MTHFR 677T allele in Mexico. Ruiz-Argüelles GJ; Coconi-Linares LN; Garcés-Eisele J; Reyes-Núñez V Hematology; 2007 Oct; 12(5):387-91. PubMed ID: 17891601 [TBL] [Abstract][Full Text] [Related]
14. High dose methotrexate treatment in childhood ALL: pilot study on the impact of the MTHFR 677C>T and 1298A>C polymorphisms on MTX-related toxicity. Haase R; Elsner K; Merkel N; Stiefel M; Mauz-Körholz C; Kramm CM; Körholz D Klin Padiatr; 2012 Apr; 224(3):156-9. PubMed ID: 22513795 [TBL] [Abstract][Full Text] [Related]
15. Functional variants of gene encoding folate metabolizing enzyme and methotrexate-related toxicity in children with acute lymphoblastic leukemia. Kałużna E; Strauss E; Zając-Spychała O; Gowin E; Świątek-Kościelna B; Nowak J; Fichna M; Mańkowski P; Januszkiewicz-Lewandowska D Eur J Pharmacol; 2015 Dec; 769():93-9. PubMed ID: 26528799 [TBL] [Abstract][Full Text] [Related]
16. Germline genetic variations in methotrexate candidate genes are associated with pharmacokinetics, toxicity, and outcome in childhood acute lymphoblastic leukemia. Radtke S; Zolk O; Renner B; Paulides M; Zimmermann M; Möricke A; Stanulla M; Schrappe M; Langer T Blood; 2013 Jun; 121(26):5145-53. PubMed ID: 23652803 [TBL] [Abstract][Full Text] [Related]
17. Polymorphisms of SLC19A1 80 G>A, MTHFR 677 C>T, and Tandem TS Repeats Influence Pharmacokinetics, Acute Liver Toxicity, and Vomiting in Children With Acute Lymphoblastic Leukemia Treated With High Doses of Methotrexate. Cwiklinska M; Czogala M; Kwiecinska K; Madetko-Talowska A; Szafarz M; Pawinska K; Wieczorek A; Klekawka T; Rej M; Stepien K; Halubiec P; Lazarczyk A; Miklusiak K; Bik-Multanowski M; Balwierz W; Skoczen S Front Pediatr; 2020; 8():307. PubMed ID: 32612964 [No Abstract] [Full Text] [Related]
18. Study of the pharmacokinetic and pharmacogenetic contribution to the toxicity of high-dose methotrexate in children with acute lymphoblastic leukemia. El-Khodary NM; El-Haggar SM; Eid MA; Ebeid EN Med Oncol; 2012 Sep; 29(3):2053-62. PubMed ID: 21644011 [TBL] [Abstract][Full Text] [Related]
19. Gene polymorphisms in folate metabolizing enzymes in adult acute lymphoblastic leukemia: effects on methotrexate-related toxicity and survival. Ongaro A; De Mattei M; Della Porta MG; Rigolin G; Ambrosio C; Di Raimondo F; Pellati A; Masieri FF; Caruso A; Catozzi L; Gemmati D Haematologica; 2009 Oct; 94(10):1391-8. PubMed ID: 19648163 [TBL] [Abstract][Full Text] [Related]
20. Influence of pre-hydration and pharmacogenetics on plasma methotrexate concentration and renal dysfunction following high-dose methotrexate therapy. Yanagimachi M; Goto H; Kaneko T; Naruto T; Sasaki K; Takeuchi M; Tanoshima R; Kato H; Yokosuka T; Kajiwara R; Fujii H; Tanaka F; Goto S; Takahashi H; Mori M; Kai S; Yokota S Int J Hematol; 2013 Dec; 98(6):702-7. PubMed ID: 24241962 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]