These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
530 related articles for article (PubMed ID: 21510863)
1. Trastuzumab-DM1 causes tumour growth inhibition by mitotic catastrophe in trastuzumab-resistant breast cancer cells in vivo. Barok M; Tanner M; Köninki K; Isola J Breast Cancer Res; 2011 Apr; 13(2):R46. PubMed ID: 21510863 [TBL] [Abstract][Full Text] [Related]
3. T-DM1, a novel antibody-drug conjugate, is highly effective against primary HER2 overexpressing uterine serous carcinoma in vitro and in vivo. English DP; Bellone S; Schwab CL; Bortolomai I; Bonazzoli E; Cocco E; Buza N; Hui P; Lopez S; Ratner E; Silasi DA; Azodi M; Schwartz PE; Rutherford TJ; Santin AD Cancer Med; 2014 Oct; 3(5):1256-65. PubMed ID: 24890382 [TBL] [Abstract][Full Text] [Related]
4. A Novel Anti-HER2 Antibody-Drug Conjugate XMT-1522 for HER2-Positive Breast and Gastric Cancers Resistant to Trastuzumab Emtansine. Le Joncour V; Martins A; Puhka M; Isola J; Salmikangas M; Laakkonen P; Joensuu H; Barok M Mol Cancer Ther; 2019 Oct; 18(10):1721-1730. PubMed ID: 31292166 [TBL] [Abstract][Full Text] [Related]
5. Trastuzumab causes antibody-dependent cellular cytotoxicity-mediated growth inhibition of submacroscopic JIMT-1 breast cancer xenografts despite intrinsic drug resistance. Barok M; Isola J; Pályi-Krekk Z; Nagy P; Juhász I; Vereb G; Kauraniemi P; Kapanen A; Tanner M; Vereb G; Szöllösi J Mol Cancer Ther; 2007 Jul; 6(7):2065-72. PubMed ID: 17620435 [TBL] [Abstract][Full Text] [Related]
6. Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance. Cretella D; Saccani F; Quaini F; Frati C; Lagrasta C; Bonelli M; Caffarra C; Cavazzoni A; Fumarola C; Galetti M; La Monica S; Ampollini L; Tiseo M; Ardizzoni A; Petronini PG; Alfieri RR Mol Cancer; 2014 Jun; 13():143. PubMed ID: 24898067 [TBL] [Abstract][Full Text] [Related]
7. An ERBB1-3 Neutralizing Antibody Mixture With High Activity Against Drug-Resistant HER2+ Breast Cancers With ERBB Ligand Overexpression. Schwarz LJ; Hutchinson KE; Rexer BN; Estrada MV; Gonzalez Ericsson PI; Sanders ME; Dugger TC; Formisano L; Guerrero-Zotano A; Red-Brewer M; Young CD; Lantto J; Pedersen MW; Kragh M; Horak ID; Arteaga CL J Natl Cancer Inst; 2017 Nov; 109(11):. PubMed ID: 29059433 [TBL] [Abstract][Full Text] [Related]
8. ARX788, a novel anti-HER2 antibody-drug conjugate, shows anti-tumor effects in preclinical models of trastuzumab emtansine-resistant HER2-positive breast cancer and gastric cancer. Barok M; Le Joncour V; Martins A; Isola J; Salmikangas M; Laakkonen P; Joensuu H Cancer Lett; 2020 Mar; 473():156-163. PubMed ID: 31904483 [TBL] [Abstract][Full Text] [Related]
9. Trastuzumab-DM1 (T-DM1) retains all the mechanisms of action of trastuzumab and efficiently inhibits growth of lapatinib insensitive breast cancer. Junttila TT; Li G; Parsons K; Phillips GL; Sliwkowski MX Breast Cancer Res Treat; 2011 Jul; 128(2):347-56. PubMed ID: 20730488 [TBL] [Abstract][Full Text] [Related]
10. Trastuzumab emtansine for HER2-positive advanced breast cancer. Verma S; Miles D; Gianni L; Krop IE; Welslau M; Baselga J; Pegram M; Oh DY; Diéras V; Guardino E; Fang L; Lu MW; Olsen S; Blackwell K; N Engl J Med; 2012 Nov; 367(19):1783-91. PubMed ID: 23020162 [TBL] [Abstract][Full Text] [Related]
11. Aberrant intracellular metabolism of T-DM1 confers T-DM1 resistance in human epidermal growth factor receptor 2-positive gastric cancer cells. Wang H; Wang W; Xu Y; Yang Y; Chen X; Quan H; Lou L Cancer Sci; 2017 Jul; 108(7):1458-1468. PubMed ID: 28388007 [TBL] [Abstract][Full Text] [Related]
12. Trastuzumab emtansine suppresses the growth of HER2-positive small-cell lung cancer in preclinical models. Morimura O; Minami T; Kijima T; Koyama S; Otsuka T; Kinehara Y; Osa A; Higashiguchi M; Miyake K; Nagatomo I; Hirata H; Iwahori K; Takimoto T; Takeda Y; Kida H; Kumanogoh A Biochem Biophys Res Commun; 2017 Jul; 488(4):596-602. PubMed ID: 28526406 [TBL] [Abstract][Full Text] [Related]
13. Trastuzumab emtansine: mechanisms of action and drug resistance. Barok M; Joensuu H; Isola J Breast Cancer Res; 2014 Mar; 16(2):209. PubMed ID: 24887180 [TBL] [Abstract][Full Text] [Related]
14. Targeting of preexisting and induced breast cancer stem cells with trastuzumab and trastuzumab emtansine (T-DM1). Diessner J; Bruttel V; Stein RG; Horn E; Häusler SF; Dietl J; Hönig A; Wischhusen J Cell Death Dis; 2014 Mar; 5(3):e1149. PubMed ID: 24675467 [TBL] [Abstract][Full Text] [Related]
15. SYD985, a novel duocarmycin-based HER2-targeting antibody-drug conjugate, shows promising antitumor activity in epithelial ovarian carcinoma with HER2/Neu expression. Menderes G; Bonazzoli E; Bellone S; Black J; Altwerger G; Masserdotti A; Pettinella F; Zammataro L; Buza N; Hui P; Wong S; Litkouhi B; Ratner E; Silasi DA; Huang GS; Azodi M; Schwartz PE; Santin AD Gynecol Oncol; 2017 Jul; 146(1):179-186. PubMed ID: 28473206 [TBL] [Abstract][Full Text] [Related]
16. Different mechanisms for resistance to trastuzumab versus lapatinib in HER2-positive breast cancers--role of estrogen receptor and HER2 reactivation. Wang YC; Morrison G; Gillihan R; Guo J; Ward RM; Fu X; Botero MF; Healy NA; Hilsenbeck SG; Phillips GL; Chamness GC; Rimawi MF; Osborne CK; Schiff R Breast Cancer Res; 2011; 13(6):R121. PubMed ID: 22123186 [TBL] [Abstract][Full Text] [Related]
17. Comparison of trastuzumab emtansine, trastuzumab deruxtecan, and disitamab vedotin in a multiresistant HER2-positive breast cancer lung metastasis model. Pourjamal N; Yazdi N; Halme A; Joncour VL; Laakkonen P; Saharinen P; Joensuu H; Barok M Clin Exp Metastasis; 2024 Apr; 41(2):91-102. PubMed ID: 38367127 [TBL] [Abstract][Full Text] [Related]
18. STAT3 activation confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive breast cancer. Wang L; Wang Q; Gao M; Fu L; Li Y; Quan H; Lou L Cancer Sci; 2018 Oct; 109(10):3305-3315. PubMed ID: 30076657 [TBL] [Abstract][Full Text] [Related]
19. Combination efficacy of pertuzumab and trastuzumab for trastuzumab emtansine-resistant cells exhibiting attenuated lysosomal trafficking or efflux pumps upregulation. Yamashita-Kashima Y; Shu S; Osada M; Fujimura T; Yoshiura S; Harada N; Yoshimura Y Cancer Chemother Pharmacol; 2020 Nov; 86(5):641-654. PubMed ID: 32997196 [TBL] [Abstract][Full Text] [Related]
20. Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate. Lewis Phillips GD; Li G; Dugger DL; Crocker LM; Parsons KL; Mai E; Blättler WA; Lambert JM; Chari RV; Lutz RJ; Wong WL; Jacobson FS; Koeppen H; Schwall RH; Kenkare-Mitra SR; Spencer SD; Sliwkowski MX Cancer Res; 2008 Nov; 68(22):9280-90. PubMed ID: 19010901 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]