BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

402 related articles for article (PubMed ID: 21513459)

  • 1. The role of body-on-a-chip devices in drug and toxicity studies.
    Esch MB; King TL; Shuler ML
    Annu Rev Biomed Eng; 2011 Aug; 13():55-72. PubMed ID: 21513459
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biofabrication of a three-dimensional liver micro-organ as an in vitro drug metabolism model.
    Chang R; Emami K; Wu H; Sun W
    Biofabrication; 2010 Dec; 2(4):045004. PubMed ID: 21079286
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Microfluidic cell culture systems for drug research.
    Wu MH; Huang SB; Lee GB
    Lab Chip; 2010 Apr; 10(8):939-56. PubMed ID: 20358102
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Microprinting of liver micro-organ for drug metabolism study.
    Chang RC; Emami K; Jeevarajan A; Wu H; Sun W
    Methods Mol Biol; 2011; 671():219-38. PubMed ID: 20967633
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Microfluidic devices for in vitro studies on liver drug metabolism and toxicity.
    van Midwoud PM; Verpoorte E; Groothuis GM
    Integr Biol (Camb); 2011 May; 3(5):509-21. PubMed ID: 21331391
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Physiologically based pharmacokinetics (PBPK).
    Espié P; Tytgat D; Sargentini-Maier ML; Poggesi I; Watelet JB
    Drug Metab Rev; 2009; 41(3):391-407. PubMed ID: 19601719
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Application of PBPK modelling in drug discovery and development at Pfizer.
    Jones HM; Dickins M; Youdim K; Gosset JR; Attkins NJ; Hay TL; Gurrell IK; Logan YR; Bungay PJ; Jones BC; Gardner IB
    Xenobiotica; 2012 Jan; 42(1):94-106. PubMed ID: 22035569
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development and application of physiologically based pharmacokinetic-modeling tools to support drug discovery.
    Lüpfert C; Reichel A
    Chem Biodivers; 2005 Nov; 2(11):1462-86. PubMed ID: 17191947
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A microfluidic device for a pharmacokinetic-pharmacodynamic (PK-PD) model on a chip.
    Sung JH; Kam C; Shuler ML
    Lab Chip; 2010 Feb; 10(4):446-55. PubMed ID: 20126684
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Applicability of bioanalysis of multiple analytes in drug discovery and development: review of select case studies including assay development considerations.
    Srinivas NR
    Biomed Chromatogr; 2006 May; 20(5):383-414. PubMed ID: 16307470
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preclinical pharmacokinetics: an approach towards safer and efficacious drugs.
    Singh SS
    Curr Drug Metab; 2006 Feb; 7(2):165-82. PubMed ID: 16472106
    [TBL] [Abstract][Full Text] [Related]  

  • 12. On setting the first dose in man: quantitating biotherapeutic drug-target binding through pharmacokinetic and pharmacodynamic models.
    Lowe PJ; Tannenbaum S; Wu K; Lloyd P; Sims J
    Basic Clin Pharmacol Toxicol; 2010 Mar; 106(3):195-209. PubMed ID: 20050847
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Microfluidic cell culture array chip for drug screening assays].
    Zheng Y; Wu J; Shao J; Jin Q; Zhao J
    Sheng Wu Gong Cheng Xue Bao; 2009 May; 25(5):779-85. PubMed ID: 19670650
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Use of physiologically based pharmacokinetic modeling for assessment of drug-drug interactions.
    Baneyx G; Fukushima Y; Parrott N
    Future Med Chem; 2012 Apr; 4(5):681-93. PubMed ID: 22458685
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PBPK models in risk assessment--A focus on chloroprene.
    DeWoskin RS
    Chem Biol Interact; 2007 Mar; 166(1-3):352-9. PubMed ID: 17324392
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The design and fabrication of three-chamber microscale cell culture analog devices with integrated dissolved oxygen sensors.
    Sin A; Chin KC; Jamil MF; Kostov Y; Rao G; Shuler ML
    Biotechnol Prog; 2004; 20(1):338-45. PubMed ID: 14763861
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Physiologically based approaches towards the prediction of pharmacokinetics: in vitro-in vivo extrapolation.
    De Buck SS; Mackie CE
    Expert Opin Drug Metab Toxicol; 2007 Dec; 3(6):865-78. PubMed ID: 18028030
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Promises, challenges and future directions of microCCAs.
    Esch MB; Sung JH; Shuler ML
    J Biotechnol; 2010 Jul; 148(1):64-9. PubMed ID: 20193719
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Pharmacokinetic and metabolic studies in the development of drugs].
    Vereczkey L
    Acta Pharm Hung; 1995 Jul; 65(4):105-11. PubMed ID: 7572191
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of a gastrointestinal tract microscale cell culture analog to predict drug transport.
    McAuliffe GJ; Chang JY; Glahn RP; Shuler ML
    Mol Cell Biomech; 2008 Jun; 5(2):119-32. PubMed ID: 18589500
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.