These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
140 related articles for article (PubMed ID: 21513881)
1. Rerouting chlorambucil to mitochondria combats drug deactivation and resistance in cancer cells. Fonseca SB; Pereira MP; Mourtada R; Gronda M; Horton KL; Hurren R; Minden MD; Schimmer AD; Kelley SO Chem Biol; 2011 Apr; 18(4):445-53. PubMed ID: 21513881 [TBL] [Abstract][Full Text] [Related]
2. A selective mitochondrial-targeted chlorambucil with remarkable cytotoxicity in breast and pancreatic cancers. Millard M; Gallagher JD; Olenyuk BZ; Neamati N J Med Chem; 2013 Nov; 56(22):9170-9. PubMed ID: 24147900 [TBL] [Abstract][Full Text] [Related]
3. Apoptosis induced by Magnolia Grandiflora extract in chlorambucil-resistant B-chronic lymphocytic leukemia cells. Marin GH; Mansilla E J Cancer Res Ther; 2010; 6(4):463-5. PubMed ID: 21358081 [TBL] [Abstract][Full Text] [Related]
4. Chlorambucil drug resistance in chronic lymphocytic leukemia: the emerging role of DNA repair. Panasci L; Paiement JP; Christodoulopoulos G; Belenkov A; Malapetsa A; Aloyz R Clin Cancer Res; 2001 Mar; 7(3):454-61. PubMed ID: 11297233 [TBL] [Abstract][Full Text] [Related]
5. Structural modifications of mitochondria-targeted chlorambucil alter cell death mechanism but preserve MDR evasion. Jean SR; Pereira MP; Kelley SO Mol Pharm; 2014 Aug; 11(8):2675-82. PubMed ID: 24922525 [TBL] [Abstract][Full Text] [Related]
7. Drug resistance to chlorambucil in murine B-cell leukemic cells is overcome by its conjugation to a targeting peptide. Gellerman G; Baskin S; Galia L; Gilad Y; Firer MA Anticancer Drugs; 2013 Feb; 24(2):112-9. PubMed ID: 23187462 [TBL] [Abstract][Full Text] [Related]
8. Bcl-2 protein expression and p53 gene mutation in chronic lymphocytic leukemia: correlation with in vitro sensitivity to chlorambucil and purine analogs. Morabito F; Filangeri M; Callea I; Sculli G; Callea V; Fracchiolla NS; Neri A; Brugiatelli M Haematologica; 1997; 82(1):16-20. PubMed ID: 9107076 [TBL] [Abstract][Full Text] [Related]
9. Acquired alkylating drug resistance of a human ovarian carcinoma cell line is unaffected by altered levels of pro- and anti-apoptotic proteins. Roy G; Horton JK; Roy R; Denning T; Mitra S; Boldogh I Oncogene; 2000 Jan; 19(1):141-50. PubMed ID: 10644989 [TBL] [Abstract][Full Text] [Related]
10. DNA repair and cellular resistance to alkylating agents in chronic lymphocytic leukemia. Müller MR; Buschfort C; Thomale J; Lensing C; Rajewsky MF; Seeber S Clin Cancer Res; 1997 Nov; 3(11):2055-61. PubMed ID: 9815597 [TBL] [Abstract][Full Text] [Related]
11. Pentostatin (Nipent) and chlorambucil with granulocyte-macrophage colony-stimulating factor support for patients with previously untreated, treated, and fludarabine-refractory B-cell chronic lymphocytic leukemia. Waselenko JK; Grever MR; Beer M; Lucas MA; Byrd JC Semin Oncol; 2000 Apr; 27(2 Suppl 5):44-51. PubMed ID: 10877052 [TBL] [Abstract][Full Text] [Related]
13. A Multi-Mitochondrial Anticancer Agent that Selectively Kills Cancer Cells and Overcomes Drug Resistance. Peng YB; Zhao ZL; Liu T; Xie GJ; Jin C; Deng TG; Sun Y; Li X; Hu XX; Zhang XB; Ye M; Tan WH ChemMedChem; 2017 Feb; 12(3):250-256. PubMed ID: 28098432 [TBL] [Abstract][Full Text] [Related]
14. Bendamustine for the treatment of chronic lymphocytic leukemia and rituximab-refractory, indolent B-cell non-Hodgkin lymphoma. Dennie TW; Kolesar JM Clin Ther; 2009; 31 Pt 2():2290-311. PubMed ID: 20110042 [TBL] [Abstract][Full Text] [Related]
15. Role of the TRAIL/APO2-L death receptors in chlorambucil- and fludarabine-induced apoptosis in chronic lymphocytic leukemia. Johnston JB; Kabore AF; Strutinsky J; Hu X; Paul JT; Kropp DM; Kuschak B; Begleiter A; Gibson SB Oncogene; 2003 Nov; 22(51):8356-69. PubMed ID: 14614459 [TBL] [Abstract][Full Text] [Related]
16. WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers. Hsiao CJ; Li TK; Chan YL; Hsin LW; Liao CH; Lee CH; Lyu PC; Guh JH Biochem Pharmacol; 2008 Feb; 75(4):847-56. PubMed ID: 18035333 [TBL] [Abstract][Full Text] [Related]
17. Mitochondria as cancer drug targets. Don AS; Hogg PJ Trends Mol Med; 2004 Aug; 10(8):372-8. PubMed ID: 15310457 [TBL] [Abstract][Full Text] [Related]
18. The sensitivity of chronic lymphocytic leukaemia lymphocytes to irradiation in vitro. Bentley P; Salter R; Blackmore J; Whittaker JA; Hanson JA; Champion AR Leuk Res; 1995 Dec; 19(12):985-8. PubMed ID: 8632669 [TBL] [Abstract][Full Text] [Related]
19. Chlorambucil synergizes with purine analogs in inducing in vitro cytotoxicity in B-cell chronic lymphocytic leukemia. Callea I; Console G; Sculli G; Filangeri M; Messina G; Morabito F Haematologica; 1998 Aug; 83(8):756-7. PubMed ID: 9793266 [TBL] [Abstract][Full Text] [Related]