BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 21515053)

  • 1. New indole amide derivatives as potent CRTH2 receptor antagonists.
    Zaghdane H; Boyd M; Colucci J; Simard D; Berthelette C; Leblanc Y; Wang Z; Houle R; Lévesque JF; Molinaro C; Hamel M; Stocco R; Sawyer N; Sillaots S; Gervais F; Gallant M
    Bioorg Med Chem Lett; 2011 Jun; 21(11):3471-4. PubMed ID: 21515053
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists.
    Becker DP; Flynn DL; Moormann AE; Nosal R; Villamil CI; Loeffler R; Gullikson GW; Moummi C; Yang DC
    J Med Chem; 2006 Feb; 49(3):1125-39. PubMed ID: 16451077
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chiral pyrrolo[2,3-d]pyrimidine and pyrimido[4,5-b]indole derivatives: structure-activity relationships of potent, highly stereoselective A1-adenosine receptor antagonists.
    Müller CE; Geis U; Grahner B; Lanzner W; Eger K
    J Med Chem; 1996 Jun; 39(13):2482-91. PubMed ID: 8691445
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Naphthalene/quinoline amides and sulfonylureas as potent and selective antagonists of the EP4 receptor.
    Burch JD; Farand J; Colucci J; Sturino C; Ducharme Y; Friesen RW; Lévesque JF; Gagné S; Wrona M; Therien AG; Mathieu MC; Denis D; Vigneault E; Xu D; Clark P; Rowland S; Han Y
    Bioorg Med Chem Lett; 2011 Feb; 21(3):1041-6. PubMed ID: 21215624
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Refinement of the benzodiazepine receptor site topology by structure-activity relationships of new N-(heteroarylmethyl)indol-3-ylglyoxylamides.
    Primofiore G; Da Settimo F; Marini AM; Taliani S; La Motta C; Simorini F; Novellino E; Greco G; Cosimelli B; Ehlardo M; Sala A; Besnard F; Montali M; Martini C
    J Med Chem; 2006 Apr; 49(8):2489-95. PubMed ID: 16610792
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of N-(3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-1H-indole-carboxamides as cholecystokinin antagonists.
    Lattmann E; Singh H; Boonprakob Y; Lattmann P; Sattayasai J
    J Pharm Pharmacol; 2006 Mar; 58(3):393-401. PubMed ID: 16536908
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists.
    Yaziji V; Rodríguez D; Gutiérrez-de-Terán H; Coelho A; Caamaño O; García-Mera X; Brea J; Loza MI; Cadavid MI; Sotelo E
    J Med Chem; 2011 Jan; 54(2):457-71. PubMed ID: 21186795
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and pharmacological evaluation of potent and highly selective D3 receptor ligands: inhibition of cocaine-seeking behavior and the role of dopamine D3/D2 receptors.
    Campiani G; Butini S; Trotta F; Fattorusso C; Catalanotti B; Aiello F; Gemma S; Nacci V; Novellino E; Stark JA; Cagnotto A; Fumagalli E; Carnovali F; Cervo L; Mennini T
    J Med Chem; 2003 Aug; 46(18):3822-39. PubMed ID: 12930145
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulations of the amide function of the preferential dopamine D3 agonist (R,R)-S32504: improvements of affinity and selectivity for D3 versus D2 receptors.
    Peglion JL; Poitevin C; Mannoury La Cour C; Dupuis D; Millan MJ
    Bioorg Med Chem Lett; 2009 Apr; 19(8):2133-8. PubMed ID: 19324548
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamide-derived antagonists of CC chemokine receptor 2 (CCR2).
    Yang MG; Xiao Z; Shi Q; Cherney RJ; Tebben AJ; De Lucca GV; Santella JB; Mo R; Cvijic ME; Zhao Q; Barrish JC; Carter PH
    Bioorg Med Chem Lett; 2012 Feb; 22(3):1384-7. PubMed ID: 22225639
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The discovery of novel indole-2-carboxamides as cannabinoid CB(1) receptor antagonists.
    Cowley PM; Baker J; Barn DR; Buchanan KI; Carlyle I; Clark JK; Clarkson TR; Deehan M; Edwards D; Goodwin RR; Jaap D; Kiyoi Y; Mort C; Palin R; Prosser A; Walker G; Ward N; Wishart G; Young T
    Bioorg Med Chem Lett; 2011 Jan; 21(1):497-501. PubMed ID: 21075628
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of indole-containing tetracycles as a new scaffold for androgen receptor ligands.
    Zhang X; Li X; Allan GF; Musto A; Lundeen SG; Sui Z
    Bioorg Med Chem Lett; 2006 Jun; 16(12):3233-7. PubMed ID: 16603353
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and serotonergic activity of 3-[2-(pyrrolidin-1-yl)ethyl]indoles: potent agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B receptor.
    Sternfeld F; Guiblin AR; Jelley RA; Matassa VG; Reeve AJ; Hunt PA; Beer MS; Heald A; Stanton JA; Sohal B; Watt AP; Street LJ
    J Med Chem; 1999 Feb; 42(4):677-90. PubMed ID: 10052975
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dopamine/serotonin receptor ligands. 10: SAR Studies on azecine-type dopamine receptor ligands by functional screening at human cloned D1, D2L, and D5 receptors with a microplate reader based calcium assay lead to a novel potent D1/D5 selective antagonist.
    Hoefgen B; Decker M; Mohr P; Schramm AM; Rostom SA; El-Subbagh H; Schweikert PM; Rudolf DR; Kassack MU; Lehmann J
    J Med Chem; 2006 Jan; 49(2):760-9. PubMed ID: 16420061
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substituted 3-(phenylmethyl)-1H-indole-5-carboxamides and 1-(phenylmethyl)indole-6-carboxamides as potent, selective, orally active antagonists of the peptidoleukotrienes.
    Jacobs RT; Brown FJ; Cronk LA; Aharony D; Buckner CK; Kusner EJ; Kirkland KM; Neilson KL
    J Med Chem; 1993 Feb; 36(3):394-409. PubMed ID: 8381184
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of novel 3-substituted-indole derivatives as selective H3 receptor antagonists and potent free radical scavengers.
    Tang L; Zhao L; Hong L; Yang F; Sheng R; Chen J; Shi Y; Zhou N; Hu Y
    Bioorg Med Chem; 2013 Oct; 21(19):5936-44. PubMed ID: 23978359
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of prostaglandin D2 receptor antagonists based on a tetrahydropyridoindole scaffold.
    Beaulieu C; Guay D; Wang Z; Leblanc Y; Roy P; Dufresne C; Zamboni R; Berthelette C; Day S; Tsou N; Denis D; Greig G; Mathieu MC; O'Neill G
    Bioorg Med Chem Lett; 2008 Apr; 18(8):2696-700. PubMed ID: 18359630
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of nonsteroidal glucocorticoid receptor ligands based on 6-indole-1,2,3,4-tetrahydroquinolines.
    Roach SL; Higuchi RI; Adams ME; Liu Y; Karanewsky DS; Marschke KB; Mais DE; Miner JN; Zhi L
    Bioorg Med Chem Lett; 2008 Jun; 18(12):3504-8. PubMed ID: 18513967
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands.
    Primofiore G; Taliani S; Da Settimo F; Marini AM; La Motta C; Simorini F; Patrizi MP; Sergianni V; Novellino E; Greco G; Cosimelli B; Calderone V; Montali M; Besnard F; Martini C
    J Med Chem; 2007 Apr; 50(7):1627-34. PubMed ID: 17335185
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of novel 1,2,3,4-tetrahydroisoquinoline derivatives and closely related compounds as potent and selective dopamine D3 receptor ligands.
    Mach UR; Hackling AE; Perachon S; Ferry S; Wermuth CG; Schwartz JC; Sokoloff P; Stark H
    Chembiochem; 2004 Apr; 5(4):508-18. PubMed ID: 15185375
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.