BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

385 related articles for article (PubMed ID: 21515403)

  • 1. Modulation of RXR function through ligand design.
    Pérez E; Bourguet W; Gronemeyer H; de Lera AR
    Biochim Biophys Acta; 2012 Jan; 1821(1):57-69. PubMed ID: 21515403
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Natural and Structure-based RXR Ligand Scaffolds and Their Functions.
    Dominguez M; Alvarez S; de Lera AR
    Curr Top Med Chem; 2017; 17(6):631-662. PubMed ID: 27320335
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Advances in drug design with RXR modulators.
    Vaz B; de Lera ÁR
    Expert Opin Drug Discov; 2012 Nov; 7(11):1003-16. PubMed ID: 22954251
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ligand Design for Modulation of RXR Functions.
    Martínez C; Souto JA; de Lera AR
    Methods Mol Biol; 2019; 2019():51-72. PubMed ID: 31359388
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A naturally occurring rexinoid, honokiol, can serve as a regulator of various retinoid x receptor heterodimers.
    Kotani H; Tanabe H; Mizukami H; Amagaya S; Inoue M
    Biol Pharm Bull; 2012; 35(1):1-9. PubMed ID: 22223330
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure basis of bigelovin as a selective RXR agonist with a distinct binding mode.
    Zhang H; Li L; Chen L; Hu L; Jiang H; Shen X
    J Mol Biol; 2011 Mar; 407(1):13-20. PubMed ID: 21262235
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists.
    Mukherjee R; Davies PJ; Crombie DL; Bischoff ED; Cesario RM; Jow L; Hamann LG; Boehm MF; Mondon CE; Nadzan AM; Paterniti JR; Heyman RA
    Nature; 1997 Mar; 386(6623):407-10. PubMed ID: 9121558
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Retinoid X Receptor Selective Agonists and their Synthetic Methods.
    Wagner CE; Jurutka PW; Marshall PA; Heck MC
    Curr Top Med Chem; 2017; 17(6):742-767. PubMed ID: 27320333
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The retinoid X receptor and its ligands: versatile regulators of metabolic function, cell differentiation and cell death.
    Ahuja HS; Szanto A; Nagy L; Davies PJ
    J Biol Regul Homeost Agents; 2003; 17(1):29-45. PubMed ID: 12757020
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modification at the acidic domain of RXR agonists has little effect on permissive RXR-heterodimer activation.
    Fujii S; Ohsawa F; Yamada S; Shinozaki R; Fukai R; Makishima M; Enomoto S; Tai A; Kakuta H
    Bioorg Med Chem Lett; 2010 Sep; 20(17):5139-42. PubMed ID: 20656484
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Retinoid X receptor ligands: a patent review (2007 - 2013).
    Yamada S; Kakuta H
    Expert Opin Ther Pat; 2014 Apr; 24(4):443-52. PubMed ID: 24456080
    [TBL] [Abstract][Full Text] [Related]  

  • 12. RAR and RXR modulation in cancer and metabolic disease.
    Altucci L; Leibowitz MD; Ogilvie KM; de Lera AR; Gronemeyer H
    Nat Rev Drug Discov; 2007 Oct; 6(10):793-810. PubMed ID: 17906642
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.
    Széles L; Póliska S; Nagy G; Szatmari I; Szanto A; Pap A; Lindstedt M; Santegoets SJ; Rühl R; Dezsö B; Nagy L
    Mol Endocrinol; 2010 Nov; 24(11):2218-31. PubMed ID: 20861222
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies.
    Pogenberg V; Guichou JF; Vivat-Hannah V; Kammerer S; Pérez E; Germain P; de Lera AR; Gronemeyer H; Royer CA; Bourguet W
    J Biol Chem; 2005 Jan; 280(2):1625-33. PubMed ID: 15528208
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biological characterization of a heterodimer-selective retinoid X receptor modulator: potential benefits for the treatment of type 2 diabetes.
    Leibowitz MD; Ardecky RJ; Boehm MF; Broderick CL; Carfagna MA; Crombie DL; D'Arrigo J; Etgen GJ; Faul MM; Grese TA; Havel H; Hein NI; Heyman RA; Jolley D; Klausing K; Liu S; Mais DE; Mapes CM; Marschke KB; Michellys PY; Montrose-Rafizadeh C; Ogilvie KM; Pascual B; Rungta D; Tyhonas JS; Urcan MS; Wardlow M; Yumibe N; Reifel-Miller A
    Endocrinology; 2006 Feb; 147(2):1044-53. PubMed ID: 16269450
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Retinoid X receptor agonists modulate Foxp3⁺ regulatory T cell and Th17 cell differentiation with differential dependence on retinoic acid receptor activation.
    Takeuchi H; Yokota-Nakatsuma A; Ohoka Y; Kagechika H; Kato C; Song SY; Iwata M
    J Immunol; 2013 Oct; 191(7):3725-33. PubMed ID: 23980207
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The "Phantom Effect" of the Rexinoid LG100754: structural and functional insights.
    Sato Y; Ramalanjaona N; Huet T; Potier N; Osz J; Antony P; Peluso-Iltis C; Poussin-Courmontagne P; Ennifar E; Mély Y; Dejaegere A; Moras D; Rochel N
    PLoS One; 2010 Nov; 5(11):e15119. PubMed ID: 21152046
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The rexinoid LG100754 is a novel RXR:PPARgamma agonist and decreases glucose levels in vivo.
    Cesario RM; Klausing K; Razzaghi H; Crombie D; Rungta D; Heyman RA; Lala DS
    Mol Endocrinol; 2001 Aug; 15(8):1360-9. PubMed ID: 11463859
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular determinants of the interactions between LXR/RXR heterodimers and TRAP220.
    Son YL; Lee YC
    Biochem Biophys Res Commun; 2009 Jul; 384(3):389-93. PubMed ID: 19410560
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of a "Gatekeeper" Antagonist that Blocks Entry Pathway to Retinoid X Receptors (RXRs) without Allosteric Ligand Inhibition in Permissive RXR Heterodimers.
    Watanabe M; Fujihara M; Motoyama T; Kawasaki M; Yamada S; Takamura Y; Ito S; Makishima M; Nakano S; Kakuta H
    J Med Chem; 2021 Jan; 64(1):430-439. PubMed ID: 33356247
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.