139 related articles for article (PubMed ID: 21520952)
1. Benzbromarone stabilizes ΔF508 CFTR at the cell surface.
Loo TW; Bartlett MC; Clarke DM
Biochemistry; 2011 May; 50(21):4393-5. PubMed ID: 21520952
[TBL] [Abstract][Full Text] [Related]
2. Corrector-mediated rescue of misprocessed CFTR mutants can be reduced by the P-glycoprotein drug pump.
Loo TW; Bartlett MC; Shi L; Clarke DM
Biochem Pharmacol; 2012 Feb; 83(3):345-54. PubMed ID: 22138447
[TBL] [Abstract][Full Text] [Related]
3. The V510D suppressor mutation stabilizes DeltaF508-CFTR at the cell surface.
Loo TW; Bartlett MC; Clarke DM
Biochemistry; 2010 Aug; 49(30):6352-7. PubMed ID: 20590134
[TBL] [Abstract][Full Text] [Related]
4. Thermally unstable gating of the most common cystic fibrosis mutant channel (ΔF508): "rescue" by suppressor mutations in nucleotide binding domain 1 and by constitutive mutations in the cytosolic loops.
Wang W; Okeyo GO; Tao B; Hong JS; Kirk KL
J Biol Chem; 2011 Dec; 286(49):41937-41948. PubMed ID: 21965669
[TBL] [Abstract][Full Text] [Related]
5. Activation of the cystic fibrosis transmembrane conductance regulator by the flavonoid quercetin: potential use as a biomarker of ΔF508 cystic fibrosis transmembrane conductance regulator rescue.
Pyle LC; Fulton JC; Sloane PA; Backer K; Mazur M; Prasain J; Barnes S; Clancy JP; Rowe SM
Am J Respir Cell Mol Biol; 2010 Nov; 43(5):607-16. PubMed ID: 20042712
[TBL] [Abstract][Full Text] [Related]
6. The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cells.
Swiatecka-Urban A; Brown A; Moreau-Marquis S; Renuka J; Coutermarsh B; Barnaby R; Karlson KH; Flotte TR; Fukuda M; Langford GM; Stanton BA
J Biol Chem; 2005 Nov; 280(44):36762-72. PubMed ID: 16131493
[TBL] [Abstract][Full Text] [Related]
7. The DeltaF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR.
Du K; Sharma M; Lukacs GL
Nat Struct Mol Biol; 2005 Jan; 12(1):17-25. PubMed ID: 15619635
[TBL] [Abstract][Full Text] [Related]
8. Low temperature and chemical rescue affect molecular proximity of DeltaF508-cystic fibrosis transmembrane conductance regulator (CFTR) and epithelial sodium channel (ENaC).
Qadri YJ; Cormet-Boyaka E; Rooj AK; Lee W; Parpura V; Fuller CM; Berdiev BK
J Biol Chem; 2012 May; 287(20):16781-90. PubMed ID: 22442149
[TBL] [Abstract][Full Text] [Related]
9. Correctors enhance maturation of DeltaF508 CFTR by promoting interactions between the two halves of the molecule.
Loo TW; Bartlett MC; Clarke DM
Biochemistry; 2009 Oct; 48(41):9882-90. PubMed ID: 19761259
[TBL] [Abstract][Full Text] [Related]
10. Annexin A5 increases the cell surface expression and the chloride channel function of the DeltaF508-cystic fibrosis transmembrane regulator.
Le Drévo MA; Benz N; Kerbiriou M; Giroux-Metges MA; Pennec JP; Trouvé P; Férec C
Biochim Biophys Acta; 2008 Oct; 1782(10):605-14. PubMed ID: 18773956
[TBL] [Abstract][Full Text] [Related]
11. Rescue of DeltaF508-CFTR (cystic fibrosis transmembrane conductance regulator) by curcumin: involvement of the keratin 18 network.
Lipecka J; Norez C; Bensalem N; Baudouin-Legros M; Planelles G; Becq F; Edelman A; Davezac N
J Pharmacol Exp Ther; 2006 May; 317(2):500-5. PubMed ID: 16424149
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of protein kinase CK2 closes the CFTR Cl channel, but has no effect on the cystic fibrosis mutant deltaF508-CFTR.
Treharne KJ; Xu Z; Chen JH; Best OG; Cassidy DM; Gruenert DC; Hegyi P; Gray MA; Sheppard DN; Kunzelmann K; Mehta A
Cell Physiol Biochem; 2009; 24(5-6):347-60. PubMed ID: 19910675
[TBL] [Abstract][Full Text] [Related]
13. Diffusional mobility of the cystic fibrosis transmembrane conductance regulator mutant, delta F508-CFTR, in the endoplasmic reticulum measured by photobleaching of GFP-CFTR chimeras.
Haggie PM; Stanton BA; Verkman AS
J Biol Chem; 2002 May; 277(19):16419-25. PubMed ID: 11877404
[TBL] [Abstract][Full Text] [Related]
14. Comparative processing and function of human and ferret cystic fibrosis transmembrane conductance regulator.
Fisher JT; Liu X; Yan Z; Luo M; Zhang Y; Zhou W; Lee BJ; Song Y; Guo C; Wang Y; Lukacs GL; Engelhardt JF
J Biol Chem; 2012 Jun; 287(26):21673-85. PubMed ID: 22570484
[TBL] [Abstract][Full Text] [Related]
15. Rescue of DeltaF508 and other misprocessed CFTR mutants by a novel quinazoline compound.
Loo TW; Bartlett MC; Clarke DM
Mol Pharm; 2005; 2(5):407-13. PubMed ID: 16196493
[TBL] [Abstract][Full Text] [Related]
16. Enhanced cell-surface stability of rescued DeltaF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones.
Varga K; Goldstein RF; Jurkuvenaite A; Chen L; Matalon S; Sorscher EJ; Bebok Z; Collawn JF
Biochem J; 2008 Mar; 410(3):555-64. PubMed ID: 18052931
[TBL] [Abstract][Full Text] [Related]
17. Activation of 3-phosphoinositide-dependent kinase 1 (PDK1) and serum- and glucocorticoid-induced protein kinase 1 (SGK1) by short-chain sphingolipid C4-ceramide rescues the trafficking defect of ΔF508-cystic fibrosis transmembrane conductance regulator (ΔF508-CFTR).
Caohuy H; Yang Q; Eudy Y; Ha TA; Xu AE; Glover M; Frizzell RA; Jozwik C; Pollard HB
J Biol Chem; 2014 Dec; 289(52):35953-68. PubMed ID: 25384981
[TBL] [Abstract][Full Text] [Related]
18. Additive effect of multiple pharmacological chaperones on maturation of CFTR processing mutants.
Wang Y; Loo TW; Bartlett MC; Clarke DM
Biochem J; 2007 Sep; 406(2):257-63. PubMed ID: 17535157
[TBL] [Abstract][Full Text] [Related]
19. Specific rescue of cystic fibrosis transmembrane conductance regulator processing mutants using pharmacological chaperones.
Wang Y; Bartlett MC; Loo TW; Clarke DM
Mol Pharmacol; 2006 Jul; 70(1):297-302. PubMed ID: 16624886
[TBL] [Abstract][Full Text] [Related]
20. The DeltaF508 mutation disrupts packing of the transmembrane segments of the cystic fibrosis transmembrane conductance regulator.
Chen EY; Bartlett MC; Loo TW; Clarke DM
J Biol Chem; 2004 Sep; 279(38):39620-7. PubMed ID: 15272010
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]