168 related articles for article (PubMed ID: 21520992)
1. Gamma-secretase inhibitor, a potential target therapy for MUC2-positive colorectal carcinoma.
Bu X; Li N; Tian X; Huang P
Neoplasma; 2011; 58(4):343-7. PubMed ID: 21520992
[TBL] [Abstract][Full Text] [Related]
2. Effects of N-[N-(3, 5-difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester (DAPT) on cell proliferation and apoptosis in Ishikawa endometrial cancer cells.
Mori M; Miyamoto T; Yakushiji H; Ohno S; Miyake Y; Sakaguchi T; Hattori M; Hongo A; Nakaizumi A; Ueda M; Ohno E
Hum Cell; 2012 Mar; 25(1):9-15. PubMed ID: 22189483
[TBL] [Abstract][Full Text] [Related]
3. [Effects of DAPT on proliferation of human dental pulp cells and Notch signaling pathway].
Zou XY; Zhuang H; Yue L; Gao XJ
Beijing Da Xue Xue Bao Yi Xue Ban; 2013 Apr; 45(2):274-9. PubMed ID: 23591351
[TBL] [Abstract][Full Text] [Related]
4. Down-regulation of Notch1 by gamma-secretase inhibition contributes to cell growth inhibition and apoptosis in ovarian cancer cells A2780.
Wang M; Wu L; Wang L; Xin X
Biochem Biophys Res Commun; 2010 Feb; 393(1):144-9. PubMed ID: 20117093
[TBL] [Abstract][Full Text] [Related]
5. [Effects of gamma-secretase inhibitor N-(3, 5-difluorophenacetyl-L-alanyl)-S-phenylglycine t-butyl ester on proliferation and differentiation of neural stem cells].
Cai LZ; Lin L; Hu JS; Zheng ZH
Zhonghua Yi Xue Za Zhi; 2008 Feb; 88(7):480-3. PubMed ID: 18642791
[TBL] [Abstract][Full Text] [Related]
6. [Expression of Notch intracellular domain in cervical cancer and effect of DAPT on cervical cancer cell].
Sun XM; Wen HW; Chen CL; Liao QP
Zhonghua Fu Chan Ke Za Zhi; 2009 May; 44(5):369-73. PubMed ID: 19573314
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of Notch signaling pathway using γ-secretase inhibitor delivered by a low dose of Triton-X100 in cultured oral cancer cells.
Nasrin A; Hassan M; Ye P
Biochem Biophys Res Commun; 2018 Jan; 495(3):2118-2124. PubMed ID: 29253571
[TBL] [Abstract][Full Text] [Related]
8. Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein.
Yang T; Arslanova D; Gu Y; Augelli-Szafran C; Xia W
Mol Brain; 2008 Nov; 1():15. PubMed ID: 18983676
[TBL] [Abstract][Full Text] [Related]
9. Pretreatment with the γ-secretase inhibitor DAPT sensitizes drug-resistant ovarian cancer cells to cisplatin by downregulation of Notch signaling.
Wang M; Ma X; Wang J; Wang L; Wang Y
Int J Oncol; 2014 Apr; 44(4):1401-9. PubMed ID: 24535252
[TBL] [Abstract][Full Text] [Related]
10. Down-regulation of Notch signaling by a γ-secretase inhibitor enhances the radiosensitivity of nasopharyngeal carcinoma cells.
Yu S; Zhang R; Liu F; Hu H; Yu S; Wang H
Oncol Rep; 2011 Nov; 26(5):1323-8. PubMed ID: 21805038
[TBL] [Abstract][Full Text] [Related]
11. C-terminal fragment of presenilin is the molecular target of a dipeptidic gamma-secretase-specific inhibitor DAPT (N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester).
Morohashi Y; Kan T; Tominari Y; Fuwa H; Okamura Y; Watanabe N; Sato C; Natsugari H; Fukuyama T; Iwatsubo T; Tomita T
J Biol Chem; 2006 May; 281(21):14670-6. PubMed ID: 16569643
[TBL] [Abstract][Full Text] [Related]
12. Suppression of mucin 2 enhances the proliferation and invasion of LS174T human colorectal cancer cells.
Bu X; Li L; Li N; Tian X; Huang P
Cell Biol Int; 2011 Nov; 35(11):1121-9. PubMed ID: 21605079
[TBL] [Abstract][Full Text] [Related]
13. gamma-secretase inhibitor induces adipogenesis of adipose-derived stem cells by regulation of Notch and PPAR-gamma.
Huang Y; Yang X; Wu Y; Jing W; Cai X; Tang W; Liu L; Liu Y; Grottkau BE; Lin Y
Cell Prolif; 2010 Apr; 43(2):147-56. PubMed ID: 20447060
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of gamma-secretases alters both proliferation and differentiation of mesenchymal stem cells.
Vujovic S; Henderson SR; Flanagan AM; Clements MO
Cell Prolif; 2007 Apr; 40(2):185-95. PubMed ID: 17472726
[TBL] [Abstract][Full Text] [Related]
15. γ-secretase inhibitor DAPT sensitizes t-AUCB-induced apoptosis of human glioblastoma cells in vitro via blocking the p38 MAPK/MAPKAPK2/Hsp27 pathway.
Li JY; Li RJ; Wang HD
Acta Pharmacol Sin; 2014 Jun; 35(6):825-31. PubMed ID: 24793313
[TBL] [Abstract][Full Text] [Related]
16. Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.
Konishi J; Kawaguchi KS; Vo H; Haruki N; Gonzalez A; Carbone DP; Dang TP
Cancer Res; 2007 Sep; 67(17):8051-7. PubMed ID: 17804716
[TBL] [Abstract][Full Text] [Related]
17. Nuclear factor-κB/p65 responds to changes in the Notch signaling pathway in murine BV-2 cells and in amoeboid microglia in postnatal rats treated with the γ-secretase complex blocker DAPT.
Cao Q; Li P; Lu J; Dheen ST; Kaur C; Ling EA
J Neurosci Res; 2010 Sep; 88(12):2701-14. PubMed ID: 20648656
[TBL] [Abstract][Full Text] [Related]
18. Blocking the NOTCH pathway can inhibit the growth of CD133-positive A549 cells and sensitize to chemotherapy.
Liu J; Mao Z; Huang J; Xie S; Liu T; Mao Z
Biochem Biophys Res Commun; 2014 Feb; 444(4):670-5. PubMed ID: 24502949
[TBL] [Abstract][Full Text] [Related]
19. Gamma secretase inhibitor impairs epithelial-to-mesenchymal transition induced by TGF-β in ovarian tumor cell lines.
Pazos MC; Abramovich D; Bechis A; Accialini P; Parborell F; Tesone M; Irusta G
Mol Cell Endocrinol; 2017 Jan; 440():125-137. PubMed ID: 27908834
[TBL] [Abstract][Full Text] [Related]
20. [Suppressive effects of gamma-secretase inhibitor DAPT on the proliferation of pancreatic cancer cells].
Du X; Cheng Z; Li Y; Zhou ZG; Yang L; Zhang MM
Sichuan Da Xue Xue Bao Yi Xue Ban; 2013 Sep; 44(5):699-702. PubMed ID: 24325093
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]