These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 21524095)

  • 21. Metabolic syndromes and malignant transformation: where the twain shall meet.
    Bhagwat N; Levine RL
    Sci Transl Med; 2010 Oct; 2(54):54ps50. PubMed ID: 20962328
    [TBL] [Abstract][Full Text] [Related]  

  • 22. An olive oil phenolic is a new chemotype of mutant isocitrate dehydrogenase 1 (IDH1) inhibitors.
    Verdura S; Cuyàs E; Lozano-Sánchez J; Bastidas-Velez C; Llorach-Parés L; Fernández-Arroyo S; Hernández-Aguilera A; Joven J; Nonell-Canals A; Bosch-Barrera J; Martin-Castillo B; Vellon L; Sanchez-Martinez M; Segura-Carretero A; Menendez JA
    Carcinogenesis; 2019 Mar; 40(1):27-40. PubMed ID: 30428017
    [TBL] [Abstract][Full Text] [Related]  

  • 23. IDH2 compensates for IDH1 mutation to maintain cell survival under hypoxic conditions in IDH1‑mutant tumor cells.
    Zhang Y; Lv W; Li Q; Wang Q; Ru Y; Xiong X; Yan F; Pan T; Lin W; Li X
    Mol Med Rep; 2019 Aug; 20(2):1893-1900. PubMed ID: 31257503
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.
    Hartmann C; Meyer J; Balss J; Capper D; Mueller W; Christians A; Felsberg J; Wolter M; Mawrin C; Wick W; Weller M; Herold-Mende C; Unterberg A; Jeuken JW; Wesseling P; Reifenberger G; von Deimling A
    Acta Neuropathol; 2009 Oct; 118(4):469-74. PubMed ID: 19554337
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Enzymatic assay for quantitative analysis of (D)-2-hydroxyglutarate.
    Balss J; Pusch S; Beck AC; Herold-Mende C; Krämer A; Thiede C; Buckel W; Langhans CD; Okun JG; von Deimling A
    Acta Neuropathol; 2012 Dec; 124(6):883-91. PubMed ID: 23117877
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Sells.
    Badur MG; Muthusamy T; Parker SJ; Ma S; McBrayer SK; Cordes T; Magana JH; Guan KL; Metallo CM
    Cell Rep; 2018 Oct; 25(4):1018-1026.e4. PubMed ID: 30355481
    [TBL] [Abstract][Full Text] [Related]  

  • 27. An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity.
    Luna LA; Lesecq Z; White KA; Hoang A; Scott DA; Zagnitko O; Bobkov AA; Barber DL; Schiffer JM; Isom DG; Sohl CD
    Biochem J; 2020 Aug; 477(16):2999-3018. PubMed ID: 32729927
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Isocitrate dehydrogenase 1/2 mutational analyses and 2-hydroxyglutarate measurements in Wilms tumors.
    Rakheja D; Mitui M; Boriack RL; DeBerardinis RJ
    Pediatr Blood Cancer; 2011 Mar; 56(3):379-83. PubMed ID: 21225914
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Kinetic and physiological effects of alterations in homologous isocitrate-binding sites of yeast NAD(+)-specific isocitrate dehydrogenase.
    Lin AP; McCammon MT; McAlister-Henn L
    Biochemistry; 2001 Nov; 40(47):14291-301. PubMed ID: 11714283
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Implication by site-directed mutagenesis of Arg314 and Tyr316 in the coenzyme site of pig mitochondrial NADP-dependent isocitrate dehydrogenase.
    Lee P; Colman RF
    Arch Biochem Biophys; 2002 May; 401(1):81-90. PubMed ID: 12054490
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Single arginine mutation in two yeast isocitrate dehydrogenases: biochemical characterization and functional implication.
    Song P; Wei H; Cao Z; Wang P; Zhu G
    PLoS One; 2014; 9(12):e115025. PubMed ID: 25502799
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Role of alpha-Asp181, beta-Asp192, and gamma-Asp190 in the distinctive subunits of human NAD-specific isocitrate dehydrogenase.
    Bzymek KP; Colman RF
    Biochemistry; 2007 May; 46(18):5391-7. PubMed ID: 17432878
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Proteomic analysis of oligodendrogliomas expressing a mutant isocitrate dehydrogenase-1.
    Thirant C; Varlet P; Lipecka J; Le Gall M; Broussard C; Chafey P; Studler JM; Lacombe J; Lions S; Guillaudeau A; Camoin L; Daumas-Duport C; Junier MP; Chneiweiss H
    Proteomics; 2011 Nov; 11(21):4139-54. PubMed ID: 21898821
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Isocitrate dehydrogenase mutations: a challenge to traditional views on the genesis and malignant progression of gliomas.
    Weller M; Wick W; von Deimling A
    Glia; 2011 Aug; 59(8):1200-4. PubMed ID: 21294161
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Cancer-associated isocitrate dehydrogenase mutations inactivate NADPH-dependent reductive carboxylation.
    Leonardi R; Subramanian C; Jackowski S; Rock CO
    J Biol Chem; 2012 Apr; 287(18):14615-20. PubMed ID: 22442146
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Segregation of non-p.R132H mutations in IDH1 in distinct molecular subtypes of glioma.
    Gravendeel LA; Kloosterhof NK; Bralten LB; van Marion R; Dubbink HJ; Dinjens W; Bleeker FE; Hoogenraad CC; Michiels E; Kros JM; van den Bent M; Smitt PA; French PJ
    Hum Mutat; 2010 Mar; 31(3):E1186-99. PubMed ID: 20077503
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Discovery of a Novel Chemical Scaffold Against Mutant Isocitrate Dehydrogenase 1 (IDH1).
    Kang CH; Choi SU; Son YH; Lee HK; Jeong HG; Yun CS; Ahn S; Park CH
    Anticancer Res; 2020 Sep; 40(9):4929-4935. PubMed ID: 32878781
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Glioma-derived mutations in IDH: from mechanism to potential therapy.
    Fu Y; Huang R; Du J; Yang R; An N; Liang A
    Biochem Biophys Res Commun; 2010 Jun; 397(2):127-30. PubMed ID: 20510884
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cancer-associated IDH mutations: biomarker and therapeutic opportunities.
    Yen KE; Bittinger MA; Su SM; Fantin VR
    Oncogene; 2010 Dec; 29(49):6409-17. PubMed ID: 20972461
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Novel allosteric properties produced by residue substitutions in the subunit interface of yeast NAD+-specific isocitrate dehydrogenase.
    Hu G; McAlister-Henn L
    Arch Biochem Biophys; 2006 Sep; 453(2):207-16. PubMed ID: 16884682
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.