These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 21525000)

  • 1. Phospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes.
    Jaafar R; Zeiller C; Pirola L; Di Grazia A; Naro F; Vidal H; Lefai E; Némoz G
    J Biol Chem; 2011 Jun; 286(25):22609-21. PubMed ID: 21525000
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin.
    Toschi A; Lee E; Xu L; Garcia A; Gadir N; Foster DA
    Mol Cell Biol; 2009 Mar; 29(6):1411-20. PubMed ID: 19114562
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of AMPK/TSC2/PLD by alcohol regulates mTORC1 and mTORC2 assembly in C2C12 myocytes.
    Hong-Brown LQ; Brown CR; Navaratnarajah M; Lang CH
    Alcohol Clin Exp Res; 2013 Nov; 37(11):1849-61. PubMed ID: 23895284
    [TBL] [Abstract][Full Text] [Related]  

  • 4. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA; Carriere A; Moreau J; Roux PP
    Mol Cell Biol; 2010 Feb; 30(4):908-21. PubMed ID: 19995915
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct amino acid-sensing mTOR pathways regulate skeletal myogenesis.
    Yoon MS; Chen J
    Mol Biol Cell; 2013 Dec; 24(23):3754-63. PubMed ID: 24068326
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts.
    Shu L; Houghton PJ
    Mol Cell Biol; 2009 Sep; 29(17):4691-700. PubMed ID: 19564418
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phospholipase D regulates the size of skeletal muscle cells through the activation of mTOR signaling.
    Jaafar R; De Larichaudy J; Chanon S; Euthine V; Durand C; Naro F; Bertolino P; Vidal H; Lefai E; Némoz G
    Cell Commun Signal; 2013 Aug; 11():55. PubMed ID: 23915343
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Constitutive activation with overexpression of the mTORC2-phospholipase D1 pathway in uterine leiomyosarcoma and STUMP: morphoproteomic analysis with therapeutic implications.
    Dhingra S; Rodriguez ME; Shen Q; Duan X; Stanton ML; Chen L; Zhang R; Brown RE
    Int J Clin Exp Pathol; 2010 Jan; 4(2):134-46. PubMed ID: 21326806
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Morphoproteomic analysis reveals an overexpressed and constitutively activated phospholipase D1-mTORC2 pathway in endometrial carcinoma.
    Shen Q; Stanton ML; Feng W; Rodriguez ME; Ramondetta L; Chen L; Brown RE; Duan X
    Int J Clin Exp Pathol; 2010 Nov; 4(1):13-21. PubMed ID: 21228924
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Platelet-derived growth factor-induced Akt phosphorylation requires mTOR/Rictor and phospholipase C-γ1, whereas S6 phosphorylation depends on mTOR/Raptor and phospholipase D.
    Razmara M; Heldin CH; Lennartsson J
    Cell Commun Signal; 2013 Jan; 11(1):3. PubMed ID: 23311350
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
    Guertin DA; Stevens DM; Thoreen CC; Burds AA; Kalaany NY; Moffat J; Brown M; Fitzgerald KJ; Sabatini DM
    Dev Cell; 2006 Dec; 11(6):859-71. PubMed ID: 17141160
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid.
    Kam Y; Exton JH
    FASEB J; 2004 Feb; 18(2):311-9. PubMed ID: 14769825
    [TBL] [Abstract][Full Text] [Related]  

  • 13. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
    García-Martínez JM; Alessi DR
    Biochem J; 2008 Dec; 416(3):375-85. PubMed ID: 18925875
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
    J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enhanced Akt phosphorylation and myogenic differentiation in PI3K p110β-deficient myoblasts is mediated by PI3K p110α and mTORC2.
    Matheny RW; Lynch CM; Leandry LA
    Growth Factors; 2012 Dec; 30(6):367-84. PubMed ID: 23137199
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological inhibition of S6K1 increases glucose metabolism and Akt signalling in vitro and in diet-induced obese mice.
    Shum M; Bellmann K; St-Pierre P; Marette A
    Diabetologia; 2016 Mar; 59(3):592-603. PubMed ID: 26733005
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Simulated microgravity inhibits C2C12 myogenesis via phospholipase D2-induced Akt/FOXO1 regulation.
    Baek MO; Ahn CB; Cho HJ; Choi JY; Son KH; Yoon MS
    Sci Rep; 2019 Oct; 9(1):14910. PubMed ID: 31624287
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alcohol-induced modulation of rictor and mTORC2 activity in C2C12 myoblasts.
    Hong-Brown LQ; Brown CR; Navaratnarajah M; Huber DS; Lang CH
    Alcohol Clin Exp Res; 2011 Aug; 35(8):1445-53. PubMed ID: 21438886
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phospholipase D is involved in myogenic differentiation through remodeling of actin cytoskeleton.
    Komati H; Naro F; Mebarek S; De Arcangelis V; Adamo S; Lagarde M; Prigent AF; Némoz G
    Mol Biol Cell; 2005 Mar; 16(3):1232-44. PubMed ID: 15616193
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.
    Chen L; Xu B; Liu L; Liu C; Luo Y; Chen X; Barzegar M; Chung J; Huang S
    Oncotarget; 2015 Mar; 6(9):7136-50. PubMed ID: 25762619
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.