These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

341 related articles for article (PubMed ID: 21527421)

  • 1. MLN4924 is an efficient inhibitor of NEDD8 conjugation in plants.
    Hakenjos JP; Richter R; Dohmann EM; Katsiarimpa A; Isono E; Schwechheimer C
    Plant Physiol; 2011 Jun; 156(2):527-36. PubMed ID: 21527421
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.
    Lan H; Tang Z; Jin H; Sun Y
    Sci Rep; 2016 Apr; 6():24218. PubMed ID: 27063292
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells.
    Luo Z; Pan Y; Jeong LS; Liu J; Jia L
    Autophagy; 2012 Nov; 8(11):1677-9. PubMed ID: 22874562
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells.
    Wang Y; Luo Z; Pan Y; Wang W; Zhou X; Jeong LS; Chu Y; Liu J; Jia L
    Cancer Biol Ther; 2015; 16(3):420-9. PubMed ID: 25782162
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DENEDDYLASE1 deconjugates NEDD8 from non-cullin protein substrates in Arabidopsis thaliana.
    Mergner J; Heinzlmeir S; Kuster B; Schwechheimer C
    Plant Cell; 2015 Mar; 27(3):741-53. PubMed ID: 25783028
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lack of SMALL ACIDIC PROTEIN 1 (SMAP1) causes increased sensitivity to an inhibitor of RUB/NEDD8-activating enzyme in Arabidopsis seedlings.
    Oono Y; Nakasone A
    Plant Signal Behav; 2013 Oct; 8(10):. PubMed ID: 24270629
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DENEDDYLASE1 Protein Counters Automodification of Neddylating Enzymes to Maintain NEDD8 Protein Homeostasis in
    Mergner J; Kuster B; Schwechheimer C
    J Biol Chem; 2017 Mar; 292(9):3854-3865. PubMed ID: 28096463
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MLN4924 suppresses neddylation and induces cell cycle arrest, senescence, and apoptosis in human osteosarcoma.
    Zhang Y; Shi CC; Zhang HP; Li GQ; Li SS
    Oncotarget; 2016 Jul; 7(29):45263-45274. PubMed ID: 27223074
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice.
    Yu H; Luo H; Chang L; Wang S; Geng X; Kang L; Zhong Y; Cao Y; Wang R; Yang X; Zhu Y; Shi MJ; Hu Y; Liu Z; Yin X; Ran Y; Yang H; Fan W; Zhao BQ
    Proc Natl Acad Sci U S A; 2022 Feb; 119(6):. PubMed ID: 35101976
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy.
    Zhao Y; Morgan MA; Sun Y
    Antioxid Redox Signal; 2014 Dec; 21(17):2383-400. PubMed ID: 24410571
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Suppression of tumor angiogenesis by targeting the protein neddylation pathway.
    Yao WT; Wu JF; Yu GY; Wang R; Wang K; Li LH; Chen P; Jiang YN; Cheng H; Lee HW; Yu J; Qi H; Yu XJ; Wang P; Chu YW; Yang M; Hua ZC; Ying HQ; Hoffman RM; Jeong LS; Jia LJ
    Cell Death Dis; 2014 Feb; 5(2):e1059. PubMed ID: 24525735
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibiting Neddylation with MLN4924 Suppresses Growth and Delays Multicellular Development in
    Huber RJ; Kim WD; Mathavarajah S
    Biomolecules; 2021 Mar; 11(3):. PubMed ID: 33807046
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of neddylation represses lipopolysaccharide-induced proinflammatory cytokine production in macrophage cells.
    Chang FM; Reyna SM; Granados JC; Wei SJ; Innis-Whitehouse W; Maffi SK; Rodriguez E; Slaga TJ; Short JD
    J Biol Chem; 2012 Oct; 287(42):35756-35767. PubMed ID: 22927439
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nedd8-Activating Enzyme Is a Druggable Host Dependency Factor of Human and Mouse Cytomegalovirus.
    Flores-Martínez YA; Le-Trilling VTK; Trilling M
    Viruses; 2021 Aug; 13(8):. PubMed ID: 34452475
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MLN4924 (Pevonedistat), a protein neddylation inhibitor, suppresses proliferation and migration of human clear cell renal cell carcinoma.
    Tong S; Si Y; Yu H; Zhang L; Xie P; Jiang W
    Sci Rep; 2017 Jul; 7(1):5599. PubMed ID: 28717191
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of neddylation induces mitotic defects and alters MKLP1 accumulation at the midbody during cytokinesis.
    Chung D; Salsman J; Dellaire G
    Cell Cycle; 2019 May; 18(10):1135-1153. PubMed ID: 31057046
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cullin neddylation inhibitor attenuates hyperglycemia by enhancing hepatic insulin signaling through insulin receptor substrate stabilization.
    Chen C; Gu L; Matye DJ; Clayton YD; Hasan MN; Wang Y; Friedman JE; Li T
    Proc Natl Acad Sci U S A; 2022 Feb; 119(6):. PubMed ID: 35115401
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Suppression of glioblastoma by targeting the overactivated protein neddylation pathway.
    Hua W; Li C; Yang Z; Li L; Jiang Y; Yu G; Zhu W; Liu Z; Duan S; Chu Y; Yang M; Zhang Y; Mao Y; Jia L
    Neuro Oncol; 2015 Oct; 17(10):1333-43. PubMed ID: 25904638
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of p21-dependent senescence by an NAE inhibitor, MLN4924, as a mechanism of growth suppression.
    Jia L; Li H; Sun Y
    Neoplasia; 2011 Jun; 13(6):561-9. PubMed ID: 21677879
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Diverse and pivotal roles of neddylation in metabolism and immunity.
    Zou T; Zhang J
    FEBS J; 2021 Jul; 288(13):3884-3912. PubMed ID: 33025631
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.