BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

278 related articles for article (PubMed ID: 21527497)

  • 1. Glucocorticoid receptor alpha isoform-selective regulation of antiapoptotic genes in osteosarcoma cells: a new mechanism for glucocorticoid resistance.
    Gross KL; Oakley RH; Scoltock AB; Jewell CM; Cidlowski JA
    Mol Endocrinol; 2011 Jul; 25(7):1087-99. PubMed ID: 21527497
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overexpression of the human glucocorticoid receptor alpha and beta isoforms inhibits AP-1 and NF-kappaB activities hormone independently.
    Gougat C; Jaffuel D; Gagliardo R; Henriquet C; Bousquet J; Demoly P; Mathieu M
    J Mol Med (Berl); 2002 May; 80(5):309-18. PubMed ID: 12021843
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The mRNA Expression and Regulation of Glucocorticoid Receptor Isoforms Associated with Response of Multiple Myeloma Treated with a Glucocorticoids-Dependent Regimen of Dexamethasone, Bortezomib and Thalidomide.
    Guan Y; Si Y; Cai W; Ma L; Fang M
    Ann Clin Lab Sci; 2021 Nov; 51(6):805-817. PubMed ID: 34921034
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein 14-3-3sigma interacts with and favors cytoplasmic subcellular localization of the glucocorticoid receptor, acting as a negative regulator of the glucocorticoid signaling pathway.
    Kino T; Souvatzoglou E; De Martino MU; Tsopanomihalu M; Wan Y; Chrousos GP
    J Biol Chem; 2003 Jul; 278(28):25651-6. PubMed ID: 12730237
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Complex human glucocorticoid receptor dim mutations define glucocorticoid induced apoptotic resistance in bone cells.
    Jewell CM; Scoltock AB; Hamel BL; Yudt MR; Cidlowski JA
    Mol Endocrinol; 2012 Feb; 26(2):244-56. PubMed ID: 22174376
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor κB and c-Jun N-terminal kinase activation.
    Papi A; Contoli M; Adcock IM; Bellettato C; Padovani A; Casolari P; Stanciu LA; Barnes PJ; Johnston SL; Ito K; Caramori G
    J Allergy Clin Immunol; 2013 Nov; 132(5):1075-1085.e6. PubMed ID: 23871663
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Changes of glucocorticoid receptor isoforms expression in acute lymphoblastic leukemia correlate with glucocorticoid resistance.
    Sun X; Fang M; Guan Y; Si Y; Ma L; Wang Y; Jia Z
    Pharmazie; 2015 May; 70(5):316-21. PubMed ID: 26062300
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective glucocorticoid receptor translational isoforms reveal glucocorticoid-induced apoptotic transcriptomes.
    Wu I; Shin SC; Cao Y; Bender IK; Jafari N; Feng G; Lin S; Cidlowski JA; Schleimer RP; Lu NZ
    Cell Death Dis; 2013 Jan; 4(1):e453. PubMed ID: 23303127
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative beta isoform: a mechanism for the generation of glucocorticoid resistance.
    Webster JC; Oakley RH; Jewell CM; Cidlowski JA
    Proc Natl Acad Sci U S A; 2001 Jun; 98(12):6865-70. PubMed ID: 11381138
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of EPA on Hsp90 and GRα protein expression in multiple myeloma drug-resistant cells.
    Wu S; Chen Y; Wang X; Weng S; Zhou W; Liu Z
    BMC Cancer; 2021 Oct; 21(1):1076. PubMed ID: 34600510
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glucocorticoid Receptor α Mediates Roflumilast's Ability to Restore Dexamethasone Sensitivity in COPD.
    Reddy AT; Lakshmi SP; Banno A; Reddy RC
    Int J Chron Obstruct Pulmon Dis; 2020; 15():125-134. PubMed ID: 32021151
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear factor-kappaB- and glucocorticoid receptor alpha- mediated mechanisms in the regulation of systemic and pulmonary inflammation during sepsis and acute respiratory distress syndrome. Evidence for inflammation-induced target tissue resistance to glucocorticoids.
    Meduri GU; Muthiah MP; Carratu P; Eltorky M; Chrousos GP
    Neuroimmunomodulation; 2005; 12(6):321-38. PubMed ID: 16557033
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dexamethasone and sex regulate placental glucocorticoid receptor isoforms in mice.
    Cuffe JSM; Saif Z; Perkins AV; Moritz KM; Clifton VL
    J Endocrinol; 2017 Aug; 234(2):89-100. PubMed ID: 28490442
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Determinants of the heightened activity of glucocorticoid receptor translational isoforms.
    Bender IK; Cao Y; Lu NZ
    Mol Endocrinol; 2013 Sep; 27(9):1577-87. PubMed ID: 23820903
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucocorticoid ligands specify different interactions with NF-kappaB by allosteric effects on the glucocorticoid receptor DNA binding domain.
    Garside H; Stevens A; Farrow S; Normand C; Houle B; Berry A; Maschera B; Ray D
    J Biol Chem; 2004 Nov; 279(48):50050-9. PubMed ID: 15355994
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB.
    Bougarne N; Paumelle R; Caron S; Hennuyer N; Mansouri R; Gervois P; Staels B; Haegeman G; De Bosscher K
    Proc Natl Acad Sci U S A; 2009 May; 106(18):7397-402. PubMed ID: 19376972
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sulfasalazine sensitises human monocytic/macrophage cells for glucocorticoids by upregulation of glucocorticoid receptor alpha and glucocorticoid induced apoptosis.
    Oerlemans R; Vink J; Dijkmans BA; Assaraf YG; van Miltenburg M; van der Heijden J; Ifergan I; Lems WF; Scheper RJ; Kaspers GJ; Cloos J; Jansen G
    Ann Rheum Dis; 2007 Oct; 66(10):1289-95. PubMed ID: 17267514
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Endothelial glucocorticoid receptor promoter methylation according to dexamethasone sensitivity.
    Mata-Greenwood E; Jackson PN; Pearce WJ; Zhang L
    J Mol Endocrinol; 2015 Oct; 55(2):133-46. PubMed ID: 26242202
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Low expression of glucocorticoid receptor alpha isoform in adult immune thrombocytopenia correlates with glucocorticoid resistance.
    Ma L; Fang M; Liang Y; Xiang Y; Jia Z; Sun X; Wang Y; Qin J
    Ann Hematol; 2013 Jul; 92(7):953-60. PubMed ID: 23435844
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes.
    Lu NZ; Cidlowski JA
    Mol Cell; 2005 Apr; 18(3):331-42. PubMed ID: 15866175
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.