223 related articles for article (PubMed ID: 21528875)
1. Direct observations of conformational distributions of intrinsically disordered p53 peptides using UV Raman and explicit solvent simulations.
Xiong K; Zwier MC; Myshakina NS; Burger VM; Asher SA; Chong LT
J Phys Chem A; 2011 Sep; 115(34):9520-7. PubMed ID: 21528875
[TBL] [Abstract][Full Text] [Related]
2. Kinetic and thermodynamic effects of phosphorylation on p53 binding to MDM2.
Yadahalli S; Neira JL; Johnson CM; Tan YS; Rowling PJE; Chattopadhyay A; Verma CS; Itzhaki LS
Sci Rep; 2019 Jan; 9(1):693. PubMed ID: 30679555
[TBL] [Abstract][Full Text] [Related]
3. The cis conformation of proline leads to weaker binding of a p53 peptide to MDM2 compared to trans.
Zhan YA; Ytreberg FM
Arch Biochem Biophys; 2015 Jun; 575():22-9. PubMed ID: 25840370
[TBL] [Abstract][Full Text] [Related]
4. Characterizing the conformational landscape of MDM2-binding p53 peptides using Molecular Dynamics simulations.
Yadahalli S; Li J; Lane DP; Gosavi S; Verma CS
Sci Rep; 2017 Nov; 7(1):15600. PubMed ID: 29142290
[TBL] [Abstract][Full Text] [Related]
5. Determinants of specificity of MDM2 for the activation domains of p53 and p65: proline27 disrupts the MDM2-binding motif of p53.
Zondlo SC; Lee AE; Zondlo NJ
Biochemistry; 2006 Oct; 45(39):11945-57. PubMed ID: 17002294
[TBL] [Abstract][Full Text] [Related]
6. Multiple peptide conformations give rise to similar binding affinities: molecular simulations of p53-MDM2.
Dastidar SG; Lane DP; Verma CS
J Am Chem Soc; 2008 Oct; 130(41):13514-5. PubMed ID: 18800837
[TBL] [Abstract][Full Text] [Related]
7. Impact of Ser17 Phosphorylation on the Conformational Dynamics of the Oncoprotein MDM2.
Bueren-Calabuig JA; Michel J
Biochemistry; 2016 May; 55(17):2500-9. PubMed ID: 27050388
[TBL] [Abstract][Full Text] [Related]
8. Impact of the K24N mutation on the transactivation domain of p53 and its binding to murine double-minute clone 2.
Zhan YA; Wu H; Powell AT; Daughdrill GW; Ytreberg FM
Proteins; 2013 Oct; 81(10):1738-47. PubMed ID: 23609977
[TBL] [Abstract][Full Text] [Related]
9. Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway.
Hu M; Gu L; Li M; Jeffrey PD; Gu W; Shi Y
PLoS Biol; 2006 Feb; 4(2):e27. PubMed ID: 16402859
[TBL] [Abstract][Full Text] [Related]
10. Microsecond simulations of mdm2 and its complex with p53 yield insight into force field accuracy and conformational dynamics.
Pantelopulos GA; Mukherjee S; Voelz VA
Proteins; 2015 Sep; 83(9):1665-76. PubMed ID: 26138282
[TBL] [Abstract][Full Text] [Related]
11. Modulation of the p53-MDM2 interaction by phosphorylation of Thr18: a computational study.
Lee HJ; Srinivasan D; Coomber D; Lane DP; Verma CS
Cell Cycle; 2007 Nov; 6(21):2604-11. PubMed ID: 17957142
[TBL] [Abstract][Full Text] [Related]
12. Design of a novel MDM2 binding peptide based on the p53 family.
Madhumalar A; Lee HJ; Brown CJ; Lane D; Verma C
Cell Cycle; 2009 Sep; 8(17):2828-36. PubMed ID: 19713735
[TBL] [Abstract][Full Text] [Related]
13. Protein-peptide molecular docking with large-scale conformational changes: the p53-MDM2 interaction.
Ciemny MP; Debinski A; Paczkowska M; Kolinski A; Kurcinski M; Kmiecik S
Sci Rep; 2016 Dec; 6():37532. PubMed ID: 27905468
[TBL] [Abstract][Full Text] [Related]
14. Binding Ensembles of
Lang L; Perez A
Molecules; 2021 Jan; 26(1):. PubMed ID: 33401765
[TBL] [Abstract][Full Text] [Related]
15. Structure of the stapled p53 peptide bound to Mdm2.
Baek S; Kutchukian PS; Verdine GL; Huber R; Holak TA; Lee KW; Popowicz GM
J Am Chem Soc; 2012 Jan; 134(1):103-6. PubMed ID: 22148351
[TBL] [Abstract][Full Text] [Related]
16. Efficient Atomistic Simulation of Pathways and Calculation of Rate Constants for a Protein-Peptide Binding Process: Application to the MDM2 Protein and an Intrinsically Disordered p53 Peptide.
Zwier MC; Pratt AJ; Adelman JL; Kaus JW; Zuckerman DM; Chong LT
J Phys Chem Lett; 2016 Sep; 7(17):3440-5. PubMed ID: 27532687
[TBL] [Abstract][Full Text] [Related]
17. Conformational changes of the p53-binding cleft of MDM2 revealed by molecular dynamics simulations.
Espinoza-Fonseca LM; Trujillo-Ferrara JG
Biopolymers; 2006 Nov; 83(4):365-73. PubMed ID: 16817233
[TBL] [Abstract][Full Text] [Related]
18. Structural Adaptation of Secondary p53 Binding Sites on MDM2 and MDMX.
Higbee PS; Dayhoff GW; Anbanandam A; Varma S; Daughdrill G
J Mol Biol; 2024 Jul; 436(13):168626. PubMed ID: 38810774
[TBL] [Abstract][Full Text] [Related]
19. The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo.
Shimizu H; Burch LR; Smith AJ; Dornan D; Wallace M; Ball KL; Hupp TR
J Biol Chem; 2002 Aug; 277(32):28446-58. PubMed ID: 11925449
[TBL] [Abstract][Full Text] [Related]
20. High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx.
Czarna A; Popowicz GM; Pecak A; Wolf S; Dubin G; Holak TA
Cell Cycle; 2009 Apr; 8(8):1176-84. PubMed ID: 19305137
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
