176 related articles for article (PubMed ID: 21528880)
1. Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods.
Baumann M; Baxendale IR; Kuratli C; Ley SV; Martin RE; Schneider J
ACS Comb Sci; 2011 Jul; 13(4):405-13. PubMed ID: 21528880
[TBL] [Abstract][Full Text] [Related]
2. Innovative approaches to the design and synthesis of small molecule libraries.
Nelson A; Roche D
Bioorg Med Chem; 2015 Jun; 23(11):2613. PubMed ID: 25766626
[No Abstract] [Full Text] [Related]
3. Synthesis of 1,4,5 trisubstituted γ-lactams via a 3-component cascade reaction.
Petersen MÅ; Mortensen MA; Cohrt AE; Petersen R; Wu P; Fleury-Brégeot N; Morgentin R; Lardy C; Nielsen TE; Clausen MH
Bioorg Med Chem; 2015 Jun; 23(11):2695-8. PubMed ID: 25684425
[TBL] [Abstract][Full Text] [Related]
4. Parallel synthesis of trisubstituted formamidines: a facile and versatile procedure.
Porcheddu A; Giacomelli G; Piredda I
J Comb Chem; 2009; 11(1):126-30. PubMed ID: 19053503
[TBL] [Abstract][Full Text] [Related]
5. Lead-oriented synthesis: Investigation of organolithium-mediated routes to 3-D scaffolds and 3-D shape analysis of a virtual lead-like library.
Lüthy M; Wheldon MC; Haji-Cheteh C; Atobe M; Bond PS; O'Brien P; Hubbard RE; Fairlamb IJ
Bioorg Med Chem; 2015 Jun; 23(11):2680-94. PubMed ID: 25936257
[TBL] [Abstract][Full Text] [Related]
6. Microwave-assisted, divergent solution-phase synthesis of 1,3,6-trisubstituted pyrazolo[3,4-d]pyrimidines.
Liu J; Wang X
ACS Comb Sci; 2011 Jul; 13(4):414-20. PubMed ID: 21528879
[TBL] [Abstract][Full Text] [Related]
7. Column chromatography-free solution-phase synthesis of a natural piper-amide-like compound library.
Kim S; Lim C; Lee S; Lee S; Cho H; Lee JY; Shim DS; Park HD; Kim S
ACS Comb Sci; 2013 Apr; 15(4):208-15. PubMed ID: 23458110
[TBL] [Abstract][Full Text] [Related]
8. Current parallel chemistry principles and practice: application to the discovery of biologically active molecules.
Edwards PJ
Curr Opin Drug Discov Devel; 2009 Nov; 12(6):899-914. PubMed ID: 19894197
[TBL] [Abstract][Full Text] [Related]
9. Combinatorial library design from reagent pharmacophore fingerprints.
Chen H; Engkvist O; Blomberg N
Methods Mol Biol; 2011; 685():135-52. PubMed ID: 20981522
[TBL] [Abstract][Full Text] [Related]
10. Rapid synthesis of an array of trisubstituted urea-based soluble epoxide hydrolase inhibitors facilitated by a novel solid-phase method.
Kowalski JA; Swinamer AD; Muegge I; Eldrup AB; Kukulka A; Cywin CL; De Lombaert S
Bioorg Med Chem Lett; 2010 Jun; 20(12):3703-7. PubMed ID: 20472432
[TBL] [Abstract][Full Text] [Related]
11. Synthesis of isoxazolo[5,4-b]pyridines by microwave-assisted multi-component reactions in water.
Tu SJ; Zhang XH; Han ZG; Cao XD; Wu SS; Yan S; Hao WJ; Zhang G; Ma N
J Comb Chem; 2009; 11(3):428-32. PubMed ID: 19364093
[TBL] [Abstract][Full Text] [Related]
12. Combinatorial chemistry and the synthesis of compound libraries.
Breinbauer R; Mentel M
Methods Mol Biol; 2009; 572():73-80. PubMed ID: 20694686
[TBL] [Abstract][Full Text] [Related]
13. Disubstituted 1-aryl-4-aminopiperidine library synthesis using computational drug design and high-throughput batch and flow technologies.
Bryan MC; Hein CD; Gao H; Xia X; Eastwood H; Bruenner BA; Louie SW; Doherty EM
ACS Comb Sci; 2013 Sep; 15(9):503-11. PubMed ID: 23927004
[TBL] [Abstract][Full Text] [Related]
14. Structure-based generation of viable leads from small combinatorial libraries.
Laird ER; Blake JF
Curr Opin Drug Discov Devel; 2004 May; 7(3):354-9. PubMed ID: 15216940
[TBL] [Abstract][Full Text] [Related]
15. The design and synthesis of libraries for the discovery of antibacterial and antifungal substances.
Edwards PJ
Drug Discov Today; 2011 Mar; 16(5-6):278-9. PubMed ID: 21277383
[No Abstract] [Full Text] [Related]
16. Small molecule library synthesis using segmented flow.
Thompson CM; Poole JL; Cross JL; Akritopoulou-Zanze I; Djuric SW
Molecules; 2011 Nov; 16(11):9161-77. PubMed ID: 22048699
[TBL] [Abstract][Full Text] [Related]
17. Molecular library design using multi-objective optimization methods.
Nicolaou CA; Kannas CC
Methods Mol Biol; 2011; 685():53-69. PubMed ID: 20981518
[TBL] [Abstract][Full Text] [Related]
18. Practical synthesis of 5-aryl-3-alkylsulfonyl-phenol and 5-aryl-3-arylsulfonyl-phenol libraries.
Jeges G; Nagy T; Meszaros T; Kovacs J; Dorman G; Kowalczyk A; Goodnow RA
J Comb Chem; 2009 Mar; 11(2):327-34. PubMed ID: 19206513
[TBL] [Abstract][Full Text] [Related]
19. Solid-phase parallel synthesis of drug-like artificial 2H-benzopyran libraries.
Lee T; Gong YD
Molecules; 2012 May; 17(5):5467-96. PubMed ID: 22572931
[TBL] [Abstract][Full Text] [Related]
20. Customizable Generation of Synthetically Accessible, Local Chemical Subspaces.
Pottel J; Moitessier N
J Chem Inf Model; 2017 Mar; 57(3):454-467. PubMed ID: 28234470
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]