These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 21531559)

  • 1. Quinazolinedione sulfonamides: a novel class of competitive AMPA receptor antagonists with oral activity.
    Koller M; Lingenhoehl K; Schmutz M; Vranesic IT; Kallen J; Auberson YP; Carcache DA; Mattes H; Ofner S; Orain D; Urwyler S
    Bioorg Med Chem Lett; 2011 Jun; 21(11):3358-61. PubMed ID: 21531559
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 6-Amino quinazolinedione sulfonamides as orally active competitive AMPA receptor antagonists.
    Orain D; Ofner S; Koller M; Carcache DA; Froestl W; Allgeier H; Rasetti V; Nozulak J; Mattes H; Soldermann N; Floersheim P; Desrayaud S; Kallen J; Lingenhoehl K; Urwyler S
    Bioorg Med Chem Lett; 2012 Jan; 22(2):996-9. PubMed ID: 22197388
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and Synthesis of Selurampanel, a Novel Orally Active and Competitive AMPA Receptor Antagonist.
    Orain D; Tasdelen E; Haessig S; Koller M; Picard A; Dubois C; Lingenhoehl K; Desrayaud S; Floersheim P; Carcache D; Urwyler S; Kallen J; Mattes H
    ChemMedChem; 2017 Feb; 12(3):197-201. PubMed ID: 27863026
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new antagonists at ionotropic glutamate receptors: molecular modeling and pharmacological studies.
    Colotta V; Lenzi O; Catarzi D; Varano F; Squarcialupi L; Costagli C; Galli A; Ghelardini C; Pugliese AM; Maraula G; Coppi E; Pellegrini-Giampietro DE; Pedata F; Sabbadin D; Moro S
    Eur J Med Chem; 2012 Aug; 54():470-82. PubMed ID: 22704999
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New 7,8-ethylenedioxy-2,3-benzodiazepines as noncompetitive AMPA receptor antagonists.
    Zappalà M; Pellicanò A; Micale N; Menniti FS; Ferreri G; De Sarro G; Grasso S; De Micheli C
    Bioorg Med Chem Lett; 2006 Jan; 16(1):167-70. PubMed ID: 16216501
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and anticonvulsant evaluation of N-substituted isoquinoline AMPA receptor antagonists.
    Gitto R; De Luca L; Pagano B; Citraro R; De Sarro G; Costa L; Ciranna L; Chimirri A
    Bioorg Med Chem; 2008 Mar; 16(5):2379-84. PubMed ID: 18077172
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, biological properties, and molecular modeling investigations of novel 3,4-diarylpyrazolines as potent and selective CB(1) cannabinoid receptor antagonists.
    Lange JH; Coolen HK; van Stuivenberg HH; Dijksman JA; Herremans AH; Ronken E; Keizer HG; Tipker K; McCreary AC; Veerman W; Wals HC; Stork B; Verveer PC; den Hartog AP; de Jong NM; Adolfs TJ; Hoogendoorn J; Kruse CG
    J Med Chem; 2004 Jan; 47(3):627-43. PubMed ID: 14736243
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heterocyclic 1,7-disubstituted indole sulfonamides are potent and selective human EP3 receptor antagonists.
    Hategan G; Polozov AM; Zeller W; Cao H; Mishra RK; Kiselyov AS; Ramirez J; Halldorsdottir G; Andrésson T; Gurney ME; Singh J
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6797-800. PubMed ID: 19836233
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CNS depressant and anticonvulsant activities of some novel 3-[5-substituted 1,3,4-thiadiazole-2-yl]-2-styryl quinazoline-4(3H)-ones.
    Jatav V; Mishra P; Kashaw S; Stables JP
    Eur J Med Chem; 2008 Sep; 43(9):1945-54. PubMed ID: 18222569
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activity.
    Sleebs BE; Czabotar PE; Fairbrother WJ; Fairlie WD; Flygare JA; Huang DC; Kersten WJ; Koehler MF; Lessene G; Lowes K; Parisot JP; Smith BJ; Smith ML; Souers AJ; Street IP; Yang H; Baell JB
    J Med Chem; 2011 Mar; 54(6):1914-26. PubMed ID: 21366295
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and QSAR of quinazoline sulfonamides as highly potent human histamine H4 receptor inverse agonists.
    Smits RA; Adami M; Istyastono EP; Zuiderveld OP; van Dam CM; de Kanter FJ; Jongejan A; Coruzzi G; Leurs R; de Esch IJ
    J Med Chem; 2010 Mar; 53(6):2390-400. PubMed ID: 20192225
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 3,5-Dihydro-4H-2,3-benzodiazepine-4-thiones: a new class of AMPA receptor antagonists.
    Chimirri A; De Sarro G; De Sarro A; Gitto R; Quartarone S; Zappalà M; Constanti A; Libri V
    J Med Chem; 1998 Aug; 41(18):3409-16. PubMed ID: 9719593
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB(1) receptor antagonists.
    Lange JH; van der Neut MA; den Hartog AP; Wals HC; Hoogendoorn J; van Stuivenberg HH; van Vliet BJ; Kruse CG
    Bioorg Med Chem Lett; 2010 Mar; 20(5):1752-7. PubMed ID: 20137935
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of a novel and highly potent noncompetitive AMPA receptor antagonist.
    Gitto R; Barreca ML; De Luca L; De Sarro G; Ferreri G; Quartarone S; Russo E; Constanti A; Chimirri A
    J Med Chem; 2003 Jan; 46(1):197-200. PubMed ID: 12502375
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 8-(1H-imidazol-1-yl)-7-nitro-4(5H)-imidazo[1,2-alpha]quinoxalinone and related compounds: synthesis and structure-activity relationships for the AMPA-type non-NMDA receptor.
    Ohmori J; Shimizu-Sasamata M; Okada M; Sakamoto S
    J Med Chem; 1997 Jun; 40(13):2053-63. PubMed ID: 9207947
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a novel clinical AMPA receptor positive modulator.
    Ward SE; Harries M; Aldegheri L; Andreotti D; Ballantine S; Bax BD; Harris AJ; Harker AJ; Lund J; Melarange R; Mingardi A; Mookherjee C; Mosley J; Neve M; Oliosi B; Profeta R; Smith KJ; Smith PW; Spada S; Thewlis KM; Yusaf SP
    J Med Chem; 2010 Aug; 53(15):5801-12. PubMed ID: 20614889
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonists: synthesis and structure-activity relationships of 6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-pyrido[2,3-b]pyrazinedione and related compounds.
    Ohmori J; Kubota H; Shimizu-Sasamata M; Okada M; Sakamoto S
    J Med Chem; 1996 Mar; 39(6):1331-8. PubMed ID: 8632440
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sulfonamide derivatives of thiazolidin-4-ones with anticonvulsant activity against two seizure models: synthesis and pharmacological evaluation.
    Siddiqui N; Arshad MF; Khan SA; Ahsan W
    J Enzyme Inhib Med Chem; 2010 Aug; 25(4):485-91. PubMed ID: 20233086
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure based evolution of a novel series of positive modulators of the AMPA receptor.
    Jamieson C; Maclean JK; Brown CI; Campbell RA; Gillen KJ; Gillespie J; Kazemier B; Kiczun M; Lamont Y; Lyons AJ; Moir EM; Morrow JA; Pantling J; Rankovic Z; Smith L
    Bioorg Med Chem Lett; 2011 Jan; 21(2):805-11. PubMed ID: 21190850
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, anticonvulsant activity and molecular modeling study of some new hydrazinecarbothioamide, benzenesulfonohydrazide, and phenacylacetohydrazide analogues of 4(3H)-quinazolinone.
    Al-Salem HS; Hegazy GH; El-Taher KE; El-Messery SM; Al-Obaid AM; El-Subbagh HI
    Bioorg Med Chem Lett; 2015 Apr; 25(7):1490-9. PubMed ID: 25754489
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.