322 related articles for article (PubMed ID: 21533284)
1. Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers.
Helland Å; Anglesio MS; George J; Cowin PA; Johnstone CN; House CM; Sheppard KE; Etemadmoghadam D; Melnyk N; Rustgi AK; Phillips WA; Johnsen H; Holm R; Kristensen GB; Birrer MJ; ; Pearson RB; Børresen-Dale AL; Huntsman DG; deFazio A; Creighton CJ; Smyth GK; Bowtell DD
PLoS One; 2011 Apr; 6(4):e18064. PubMed ID: 21533284
[TBL] [Abstract][Full Text] [Related]
2. The MYCN-HMGA2-CDKN2A pathway in non-small cell lung carcinoma--differences in histological subtypes.
Eide HA; Halvorsen AR; Bjaanæs MM; Piri H; Holm R; Solberg S; Jørgensen L; Brustugun OT; Kiserud CE; Helland Å
BMC Cancer; 2016 Feb; 16():71. PubMed ID: 26858029
[TBL] [Abstract][Full Text] [Related]
3. LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.
Molenaar JJ; Domingo-Fernández R; Ebus ME; Lindner S; Koster J; Drabek K; Mestdagh P; van Sluis P; Valentijn LJ; van Nes J; Broekmans M; Haneveld F; Volckmann R; Bray I; Heukamp L; Sprüssel A; Thor T; Kieckbusch K; Klein-Hitpass L; Fischer M; Vandesompele J; Schramm A; van Noesel MM; Varesio L; Speleman F; Eggert A; Stallings RL; Caron HN; Versteeg R; Schulte JH
Nat Genet; 2012 Nov; 44(11):1199-206. PubMed ID: 23042116
[TBL] [Abstract][Full Text] [Related]
4. MYCN/LIN28B/Let-7/HMGA2 pathway implicated by meta-analysis of GWAS in suppression of post-natal proliferation thereby potentially contributing to aging.
Keane M; de Magalhães JP
Mech Ageing Dev; 2013; 134(7-8):346-8. PubMed ID: 23639551
[TBL] [Abstract][Full Text] [Related]
5. Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma.
Powers JT; Tsanov KM; Pearson DS; Roels F; Spina CS; Ebright R; Seligson M; de Soysa Y; Cahan P; Theißen J; Tu HC; Han A; Kurek KC; LaPier GS; Osborne JK; Ross SJ; Cesana M; Collins JJ; Berthold F; Daley GQ
Nature; 2016 Jul; 535(7611):246-51. PubMed ID: 27383785
[TBL] [Abstract][Full Text] [Related]
6. The oncogenic triangle of HMGA2, LIN28B and IGF2BP1 antagonizes tumor-suppressive actions of the let-7 family.
Busch B; Bley N; Müller S; Glaß M; Misiak D; Lederer M; Vetter M; Strauß HG; Thomssen C; Hüttelmaier S
Nucleic Acids Res; 2016 May; 44(8):3845-64. PubMed ID: 26917013
[TBL] [Abstract][Full Text] [Related]
7. MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma.
Beckers A; Van Peer G; Carter DR; Gartlgruber M; Herrmann C; Agarwal S; Helsmoortel HH; Althoff K; Molenaar JJ; Cheung BB; Schulte JH; Benoit Y; Shohet JM; Westermann F; Marshall GM; Vandesompele J; De Preter K; Speleman F
Cancer Lett; 2015 Sep; 366(1):123-32. PubMed ID: 26123663
[TBL] [Abstract][Full Text] [Related]
8. Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma.
Buechner J; Tømte E; Haug BH; Henriksen JR; Løkke C; Flægstad T; Einvik C
Br J Cancer; 2011 Jul; 105(2):296-303. PubMed ID: 21654684
[TBL] [Abstract][Full Text] [Related]
9. MUC1-C Induces the LIN28B→LET-7→HMGA2 Axis to Regulate Self-Renewal in NSCLC.
Alam M; Ahmad R; Rajabi H; Kufe D
Mol Cancer Res; 2015 Mar; 13(3):449-60. PubMed ID: 25368430
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells.
Buechner J; Henriksen JR; Haug BH; Tømte E; Flaegstad T; Einvik C
Differentiation; 2011 Jan; 81(1):25-34. PubMed ID: 20980091
[TBL] [Abstract][Full Text] [Related]
11. Genomic imbalances are involved in miR-30c and let-7a deregulation in ovarian tumors: implications for HMGA2 expression.
Agostini A; Brunetti M; Davidson B; Tropé CG; Heim S; Panagopoulos I; Micci F
Oncotarget; 2017 Mar; 8(13):21554-21560. PubMed ID: 28423547
[TBL] [Abstract][Full Text] [Related]
12. MYCN-regulated miRNA-92 inhibits secretion of the tumor suppressor DICKKOPF-3 (DKK3) in neuroblastoma.
Haug BH; Henriksen JR; Buechner J; Geerts D; Tømte E; Kogner P; Martinsson T; Flægstad T; Sveinbjørnsson B; Einvik C
Carcinogenesis; 2011 Jul; 32(7):1005-12. PubMed ID: 21572098
[TBL] [Abstract][Full Text] [Related]
13. [Overexpression of high mobility group A2 and its correlation with microRNA let-7 family in serous ovarian cancers].
Yang J; Zhang Q; Dong JQ; Chang XH; He XJ
Beijing Da Xue Xue Bao Yi Xue Ban; 2012 Oct; 44(5):749-54. PubMed ID: 23073586
[TBL] [Abstract][Full Text] [Related]
14. HMGA2: a biomarker significantly overexpressed in high-grade ovarian serous carcinoma.
Mahajan A; Liu Z; Gellert L; Zou X; Yang G; Lee P; Yang X; Wei JJ
Mod Pathol; 2010 May; 23(5):673-81. PubMed ID: 20228781
[TBL] [Abstract][Full Text] [Related]
15. Lin28B/Let-7 Regulates Expression of Oct4 and Sox2 and Reprograms Oral Squamous Cell Carcinoma Cells to a Stem-like State.
Chien CS; Wang ML; Chu PY; Chang YL; Liu WH; Yu CC; Lan YT; Huang PI; Lee YY; Chen YW; Lo WL; Chiou SH
Cancer Res; 2015 Jun; 75(12):2553-65. PubMed ID: 25858147
[TBL] [Abstract][Full Text] [Related]
16. ID2 expression is not associated with MYCN amplification or expression in human neuroblastomas.
Wang Q; Hii G; Shusterman S; Mosse Y; Winter CL; Guo C; Zhao H; Rappaport E; Hogarty MD; Maris JM
Cancer Res; 2003 Apr; 63(7):1631-5. PubMed ID: 12670915
[TBL] [Abstract][Full Text] [Related]
17. Expression of MYCN in pediatric synovial sarcoma.
Somers GR; Zielenska M; Abdullah S; Sherman C; Chan S; Thorner PS
Mod Pathol; 2007 Jul; 20(7):734-41. PubMed ID: 17464317
[TBL] [Abstract][Full Text] [Related]
18. FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients.
Tassi RA; Todeschini P; Siegel ER; Calza S; Cappella P; Ardighieri L; Cadei M; Bugatti M; Romani C; Bandiera E; Zanotti L; Tassone L; Guarino D; Santonocito C; Capoluongo ED; Beltrame L; Erba E; Marchini S; D'Incalci M; Donzelli C; Santin AD; Pecorelli S; Sartori E; Bignotti E; Odicino F; Ravaggi A
J Exp Clin Cancer Res; 2017 May; 36(1):63. PubMed ID: 28482906
[TBL] [Abstract][Full Text] [Related]
19. TRIM71 suppresses tumorigenesis via modulation of Lin28B-let-7-HMGA2 signaling.
Yin J; Kim TH; Park N; Shin D; Choi HI; Cho S; Park JB; Kim JH
Oncotarget; 2016 Nov; 7(48):79854-79868. PubMed ID: 27821801
[TBL] [Abstract][Full Text] [Related]
20. Lin28 promotes transformation and is associated with advanced human malignancies.
Viswanathan SR; Powers JT; Einhorn W; Hoshida Y; Ng TL; Toffanin S; O'Sullivan M; Lu J; Phillips LA; Lockhart VL; Shah SP; Tanwar PS; Mermel CH; Beroukhim R; Azam M; Teixeira J; Meyerson M; Hughes TP; Llovet JM; Radich J; Mullighan CG; Golub TR; Sorensen PH; Daley GQ
Nat Genet; 2009 Jul; 41(7):843-8. PubMed ID: 19483683
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
