These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

317 related articles for article (PubMed ID: 21536589)

  • 1. FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3.
    Araujo J; Breuer P; Dieringer S; Krauss S; Dorn S; Zimmermann K; Pfeifer A; Klockgether T; Wuellner U; Evert BO
    Hum Mol Genet; 2011 Aug; 20(15):2928-41. PubMed ID: 21536589
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Upregulation of miR-25 and miR-181 Family Members Correlates with Reduced Expression of ATXN3 in Lymphocytes from SCA3 Patients.
    Krauss S; Nalavade R; Weber S; Carter K; Evert BO
    Microrna; 2019; 8(1):76-85. PubMed ID: 30147021
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3.
    Mueller T; Breuer P; Schmitt I; Walter J; Evert BO; Wüllner U
    Hum Mol Genet; 2009 Sep; 18(17):3334-43. PubMed ID: 19542537
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3).
    Hübener J; Weber JJ; Richter C; Honold L; Weiss A; Murad F; Breuer P; Wüllner U; Bellstedt P; Paquet-Durand F; Takano J; Saido TC; Riess O; Nguyen HP
    Hum Mol Genet; 2013 Feb; 22(3):508-18. PubMed ID: 23100324
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aqueous extract of Glycyrrhiza inflata inhibits aggregation by upregulating PPARGC1A and NFE2L2-ARE pathways in cell models of spinocerebellar ataxia 3.
    Chen CM; Weng YT; Chen WL; Lin TH; Chao CY; Lin CH; Chen IC; Lee LC; Lin HY; Wu YR; Chen YC; Chang KH; Tang HY; Cheng ML; Lee-Chen GJ; Lin JY
    Free Radic Biol Med; 2014 Jun; 71():339-350. PubMed ID: 24675225
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Decreased antioxidant enzyme activity and increased mitochondrial DNA damage in cellular models of Machado-Joseph disease.
    Yu YC; Kuo CL; Cheng WL; Liu CS; Hsieh M
    J Neurosci Res; 2009 Jun; 87(8):1884-91. PubMed ID: 19185026
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Silencing mutant ATXN3 expression resolves molecular phenotypes in SCA3 transgenic mice.
    Rodríguez-Lebrón E; Costa Mdo C; Luna-Cancalon K; Peron TM; Fischer S; Boudreau RL; Davidson BL; Paulson HL
    Mol Ther; 2013 Oct; 21(10):1909-18. PubMed ID: 23820820
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gene expression profiling in ataxin-3 expressing cell lines reveals distinct effects of normal and mutant ataxin-3.
    Evert BO; Vogt IR; Vieira-Saecker AM; Ozimek L; de Vos RA; Brunt ER; Klockgether T; Wüllner U
    J Neuropathol Exp Neurol; 2003 Oct; 62(10):1006-18. PubMed ID: 14575237
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3.
    Gao R; Liu Y; Silva-Fernandes A; Fang X; Paulucci-Holthauzen A; Chatterjee A; Zhang HL; Matsuura T; Choudhary S; Ashizawa T; Koeppen AH; Maciel P; Hazra TK; Sarkar PS
    PLoS Genet; 2015 Jan; 11(1):e1004834. PubMed ID: 25590633
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of spinocerebellar ataxia type 3 mouse models identifies early gain-of-function, cell-autonomous transcriptional changes in oligodendrocytes.
    Ramani B; Panwar B; Moore LR; Wang B; Huang R; Guan Y; Paulson HL
    Hum Mol Genet; 2017 Sep; 26(17):3362-3374. PubMed ID: 28854700
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Absence of ataxin-3 leads to cytoskeletal disorganization and increased cell death.
    Rodrigues AJ; do Carmo Costa M; Silva TL; Ferreira D; Bajanca F; Logarinho E; Maciel P
    Biochim Biophys Acta; 2010 Oct; 1803(10):1154-63. PubMed ID: 20637808
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ataxin-3 protein modification as a treatment strategy for spinocerebellar ataxia type 3: removal of the CAG containing exon.
    Evers MM; Tran HD; Zalachoras I; Pepers BA; Meijer OC; den Dunnen JT; van Ommen GJ; Aartsma-Rus A; van Roon-Mom WM
    Neurobiol Dis; 2013 Oct; 58():49-56. PubMed ID: 23659897
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Druggable genome screen identifies new regulators of the abundance and toxicity of ATXN3, the Spinocerebellar Ataxia type 3 disease protein.
    Ashraf NS; Sutton JR; Yang Y; Ranxhi B; Libohova K; Shaw ED; Barget AJ; Todi SV; Paulson HL; Costa MDC
    Neurobiol Dis; 2020 Apr; 137():104697. PubMed ID: 31783119
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FOXO4 induces human plasminogen activator inhibitor-1 gene expression via an indirect mechanism by modulating HIF-1alpha and CREB levels.
    Dimova EY; Samoylenko A; Kietzmann T
    Antioxid Redox Signal; 2010 Aug; 13(4):413-24. PubMed ID: 20136501
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.
    Chatterjee A; Saha S; Chakraborty A; Silva-Fernandes A; Mandal SM; Neves-Carvalho A; Liu Y; Pandita RK; Hegde ML; Hegde PM; Boldogh I; Ashizawa T; Koeppen AH; Pandita TK; Maciel P; Sarkar PS; Hazra TK
    PLoS Genet; 2015 Jan; 11(1):e1004749. PubMed ID: 25633985
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD.
    Switonski PM; Szlachcic WJ; Krzyzosiak WJ; Figiel M
    Neurobiol Dis; 2015 Jan; 73():174-88. PubMed ID: 25301414
    [TBL] [Abstract][Full Text] [Related]  

  • 17. miR-25 alleviates polyQ-mediated cytotoxicity by silencing ATXN3.
    Huang F; Zhang L; Long Z; Chen Z; Hou X; Wang C; Peng H; Wang J; Li J; Duan R; Xia K; Chuang DM; Tang B; Jiang H
    FEBS Lett; 2014 Dec; 588(24):4791-8. PubMed ID: 25451224
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aqueous extract of Gardenia jasminoides targeting oxidative stress to reduce polyQ aggregation in cell models of spinocerebellar ataxia 3.
    Chang KH; Chen WL; Wu YR; Lin TH; Wu YC; Chao CY; Lin JY; Lee LC; Chen YC; Lee-Chen GJ; Chen CM
    Neuropharmacology; 2014 Jun; 81():166-75. PubMed ID: 24486383
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A mutant ataxin-3 fragment results from processing at a site N-terminal to amino acid 190 in brain of Machado-Joseph disease-like transgenic mice.
    Colomer Gould VF; Goti D; Pearce D; Gonzalez GA; Gao H; Bermudez de Leon M; Jenkins NA; Copeland NG; Ross CA; Brown DR
    Neurobiol Dis; 2007 Sep; 27(3):362-9. PubMed ID: 17632007
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Polyglutamine-expanded ataxin-3 is degraded by autophagy].
    Xiao H; Tang J; Hu Z; Tan J; Tang B; Jiang Z
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2010 Feb; 27(1):23-8. PubMed ID: 20140862
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.