BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 21536668)

  • 1. Neutral sphingomyelinase-2 mediates growth arrest by retinoic acid through modulation of ribosomal S6 kinase.
    Clarke CJ; Mediwala K; Jenkins RW; Sutton CA; Tholanikunnel BG; Hannun YA
    J Biol Chem; 2011 Jun; 286(24):21565-76. PubMed ID: 21536668
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cells.
    Marchesini N; Osta W; Bielawski J; Luberto C; Obeid LM; Hannun YA
    J Biol Chem; 2004 Jun; 279(24):25101-11. PubMed ID: 15051724
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATRA transcriptionally induces nSMase2 through CBP/p300-mediated histone acetylation.
    Clarke CJ; Shamseddine AA; Jacob JJ; Khalife G; Burns TA; Hannun YA
    J Lipid Res; 2016 May; 57(5):868-81. PubMed ID: 27013100
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neutral sphingomyelinase 2 (nSMase2) is the primary neutral sphingomyelinase isoform activated by tumour necrosis factor-α in MCF-7 cells.
    Clarke CJ; Cloessner EA; Roddy PL; Hannun YA
    Biochem J; 2011 Apr; 435(2):381-90. PubMed ID: 21303347
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcriptional regulation of neutral sphingomyelinase 2 in all-trans retinoic acid-treated human breast cancer cell line, MCF-7.
    Ito H; Tanaka K; Hagiwara K; Kobayashi M; Hoshikawa A; Mizutani N; Takagi A; Kojima T; Sobue S; Ichihara M; Suzuki M; Tamiya-Koizumi K; Nakamura M; Banno Y; Nozawa Y; Murate T
    J Biochem; 2012 Jun; 151(6):599-610. PubMed ID: 22496486
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism.
    Marchesini N; Luberto C; Hannun YA
    J Biol Chem; 2003 Apr; 278(16):13775-83. PubMed ID: 12566438
    [TBL] [Abstract][Full Text] [Related]  

  • 7. P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest.
    Shamseddine AA; Clarke CJ; Carroll B; Airola MV; Mohammed S; Rella A; Obeid LM; Hannun YA
    Cell Death Dis; 2015 Oct; 6(10):e1947. PubMed ID: 26512957
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Src regulates cigarette smoke-induced ceramide generation via neutral sphingomyelinase 2 in the airway epithelium.
    Chung S; Vu S; Filosto S; Goldkorn T
    Am J Respir Cell Mol Biol; 2015 Jun; 52(6):738-48. PubMed ID: 25347576
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1.
    Cinq-Frais C; Coatrieux C; Grazide MH; Hannun YA; Nègre-Salvayre A; Salvayre R; Augé N
    Biochim Biophys Acta; 2013 Aug; 1831(8):1344-56. PubMed ID: 23651497
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neutral sphingomyelinase 2 deficiency increases hyaluronan synthesis by up-regulation of Hyaluronan synthase 2 through decreased ceramide production and activation of Akt.
    Qin J; Berdyshev E; Poirer C; Schwartz NB; Dawson G
    J Biol Chem; 2012 Apr; 287(17):13620-32. PubMed ID: 22383528
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The hyaluronic acid inhibitor 4-methylumbelliferone is an NSMase2 activator-role of Ceramide in MU anti-tumor activity.
    Qin J; Kilkus J; Dawson G
    Biochim Biophys Acta; 2016 Feb; 1861(2):78-90. PubMed ID: 26548718
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neutral Sphingomyelinase 2 Mediates Oxidative Stress Effects on Astrocyte Senescence and Synaptic Plasticity Transcripts.
    Zhu Z; Quadri Z; Crivelli SM; Elsherbini A; Zhang L; Tripathi P; Qin H; Roush E; Spassieva SD; Nikolova-Karakashian M; McClintock TS; Bieberich E
    Mol Neurobiol; 2022 May; 59(5):3233-3253. PubMed ID: 35294731
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stress-induced sphingolipid signaling: role of type-2 neutral sphingomyelinase in murine cell apoptosis and proliferation.
    Devillard R; Galvani S; Thiers JC; Guenet JL; Hannun Y; Bielawski J; Nègre-Salvayre A; Salvayre R; Augé N
    PLoS One; 2010 Mar; 5(3):e9826. PubMed ID: 20352118
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transcriptional regulation of neutral sphingomyelinase 2 gene expression of a human breast cancer cell line, MCF-7, induced by the anti-cancer drug, daunorubicin.
    Ito H; Murakami M; Furuhata A; Gao S; Yoshida K; Sobue S; Hagiwara K; Takagi A; Kojima T; Suzuki M; Banno Y; Tanaka K; Tamiya-Koizumi K; Kyogashima M; Nozawa Y; Murate T
    Biochim Biophys Acta; 2009; 1789(11-12):681-90. PubMed ID: 19698806
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Early activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampi.
    Gu L; Huang B; Shen W; Gao L; Ding Z; Wu H; Guo J
    J Neuroinflammation; 2013 Sep; 10():109. PubMed ID: 24007266
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Advance in research on regulatory mechanism and functions of neutral sphingomyelinse 2].
    Zhang L; Guo J
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2013 Oct; 35(5):581-5. PubMed ID: 24183051
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Up-regulation of acid sphingomyelinase during retinoic acid-induced myeloid differentiation of NB4, a human acute promyelocytic leukemia cell line.
    Murate T; Suzuki M; Hattori M; Takagi A; Kojima T; Tanizawa T; Asano H; Hotta T; Saito H; Yoshida S; Tamiya-Koizumi K
    J Biol Chem; 2002 Mar; 277(12):9936-43. PubMed ID: 11788605
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neutral sphingomyelinase 2 induces dopamine uptake through regulation of intracellular calcium.
    Kim SK; Ahn KH; Ji JE; Choi JM; Jeon HJ; Jung SY; Jung KM; Kim DK
    Cell Signal; 2010 May; 22(5):865-70. PubMed ID: 20096352
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulated translocation of neutral sphingomyelinase-2 to the plasma membrane drives insulin resistance in steatotic hepatocytes.
    El-Amouri S; Karakashian A; Bieberich E; Nikolova-Karakashian M
    J Lipid Res; 2023 Oct; 64(10):100435. PubMed ID: 37640282
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of neutral sphingomyelinase-2 (nSMase2) by tumor necrosis factor-alpha involves protein kinase C-delta in lung epithelial cells.
    Clarke CJ; Guthrie JM; Hannun YA
    Mol Pharmacol; 2008 Oct; 74(4):1022-32. PubMed ID: 18653803
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.