BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

382 related articles for article (PubMed ID: 21536673)

  • 21. Sequence of gating charge movement and pore gating in HERG activation and deactivation pathways.
    Goodchild SJ; Macdonald LC; Fedida D
    Biophys J; 2015 Mar; 108(6):1435-1447. PubMed ID: 25809256
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Multiple mechanisms underlie reduced potassium conductance in the p.T1019PfsX38 variant of hERG.
    Al Salmani MK; Tavakoli R; Zaman W; Al Harrasi A
    Physiol Rep; 2022 Jul; 10(14):e15341. PubMed ID: 35854468
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The Susceptibilities of Human Ether-à-Go-Go-Related Gene Channel with the G487R Mutation to Arrhythmogenic Factors.
    Hisajima N; Hata Y; Kinoshita K; Fukushima T; Nishida N; Kano M; Tabata T
    Biol Pharm Bull; 2015; 38(5):781-4. PubMed ID: 25947924
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Mechanistic insight into human ether-à-go-go-related gene (hERG) K+ channel deactivation gating from the solution structure of the EAG domain.
    Muskett FW; Thouta S; Thomson SJ; Bowen A; Stansfeld PJ; Mitcheson JS
    J Biol Chem; 2011 Feb; 286(8):6184-91. PubMed ID: 21135103
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER.
    Smith JL; McBride CM; Nataraj PS; Bartos DC; January CT; Delisle BP
    Am J Physiol Cell Physiol; 2011 Jul; 301(1):C75-85. PubMed ID: 21490315
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Novel characteristics of a trafficking-defective G572R-hERG channel linked to hereditary long QT syndrome.
    Lian J; Huang N; Zhou J; Ge S; Huang X; Huo J; Liu L; Xu W; Zhang S; Yang X; Zhou J; Huang C
    Can J Cardiol; 2010 Oct; 26(8):417-22. PubMed ID: 20931094
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Targeted activation of human ether-à-go-go-related gene channels rescues electrical instability induced by the R56Q+/- long QT syndrome variant.
    Venkateshappa R; Hunter DV; Muralidharan P; Nagalingam RS; Huen G; Faizi S; Luthra S; Lin E; Cheng YM; Hughes J; Khelifi R; Dhunna DP; Johal R; Sergeev V; Shafaattalab S; Julian LM; Poburko DT; Laksman Z; Tibbits GF; Claydon TW
    Cardiovasc Res; 2023 Nov; 119(15):2522-2535. PubMed ID: 37739930
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Identification and functional characterization of the human ether-a-go-go-related gene Q738X mutant associated with hereditary long QT syndrome type 2.
    Han SN; Yang SH; Zhang Y; Sun XY; Duan YY; Hu XJ; Fan TL; Huang CZ; Yang G; Zhang Z; Zhang L
    Int J Mol Med; 2014 Sep; 34(3):810-5. PubMed ID: 24993425
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Role of intracellular domains in the function of the herg potassium channel.
    Al-Owais M; Bracey K; Wray D
    Eur Biophys J; 2009 Jun; 38(5):569-76. PubMed ID: 19172259
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Investigation of PAS and CNBH domain interactions in hERG channels and effects of long-QT syndrome-causing mutations with surface plasmon resonance.
    Soohoo SM; Tiwari PB; Suzuki YJ; Brelidze TI
    J Biol Chem; 2022 Jan; 298(1):101433. PubMed ID: 34801551
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency.
    Paulussen A; Raes A; Matthijs G; Snyders DJ; Cohen N; Aerssens J
    J Biol Chem; 2002 Dec; 277(50):48610-6. PubMed ID: 12354768
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Blockade of permeation by potassium but normal gating of the G628S nonconducting hERG channel mutant.
    Es-Salah-Lamoureux Z; Xiong PY; Goodchild SJ; Ahern CA; Fedida D
    Biophys J; 2011 Aug; 101(3):662-70. PubMed ID: 21806934
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels.
    Gianulis EC; Liu Q; Trudeau MC
    J Gen Physiol; 2013 Oct; 142(4):351-66. PubMed ID: 24043860
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Voltage-shift of the current activation in HERG S4 mutation (R534C) in LQT2.
    Nakajima T; Furukawa T; Hirano Y; Tanaka T; Sakurada H; Takahashi T; Nagai R; Itoh T; Katayama Y; Nakamura Y; Hiraoka M
    Cardiovasc Res; 1999 Nov; 44(2):283-93. PubMed ID: 10690305
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of the cyclic-nucleotide-binding domain as a conserved determinant of ion-channel cell-surface localization.
    Akhavan A; Atanasiu R; Noguchi T; Han W; Holder N; Shrier A
    J Cell Sci; 2005 Jul; 118(Pt 13):2803-12. PubMed ID: 15961404
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The G604S-hERG mutation alters the biophysical properties and exerts a dominant-negative effect on expression of hERG channels in HEK293 cells.
    Huo J; Zhang Y; Huang N; Liu P; Huang C; Guo X; Jiang W; Zhou N; Grace A; Huang CL; Ma A
    Pflugers Arch; 2008 Aug; 456(5):917-28. PubMed ID: 18386051
    [TBL] [Abstract][Full Text] [Related]  

  • 37. HERG channel (dys)function revealed by dynamic action potential clamp technique.
    Berecki G; Zegers JG; Verkerk AO; Bhuiyan ZA; de Jonge B; Veldkamp MW; Wilders R; van Ginneken AC
    Biophys J; 2005 Jan; 88(1):566-78. PubMed ID: 15475579
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Differential Effects of Remdesivir and Lumacaftor on Homomeric and Heteromeric hERG Channels.
    Campagna N; Wall E; Lee K; Guo J; Li W; Yang T; Baranchuk A; El-Diasty M; Zhang S
    Mol Pharmacol; 2023 Oct; 104(4):164-173. PubMed ID: 37419691
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating.
    Viloria CG; Barros F; Giráldez T; Gómez-Varela D; de la Peña P
    Biophys J; 2000 Jul; 79(1):231-46. PubMed ID: 10866950
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mouse ERG K(+) channel clones reveal differences in protein trafficking and function.
    Lin EC; Moungey BM; Lim E; Concannon SP; Anderson CL; Kyle JW; Makielski JC; Balijepalli SY; January CT
    J Am Heart Assoc; 2014 Dec; 3(6):e001491. PubMed ID: 25497881
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 20.