BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 21538436)

  • 1. Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis.
    Meyer zu Schwabedissen HE; Ware JA; Finkelstein D; Chaudhry AS; Mansell S; Leon-Ponte M; Strom SC; Zaher H; Schwarz UI; Freeman DJ; Schuetz EG; Tirona RG; Kim RB
    Hepatology; 2011 Aug; 54(2):644-54. PubMed ID: 21538436
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Contribution of hepatic organic anion-transporting polypeptides to docetaxel uptake and clearance.
    Lee HH; Leake BF; Teft W; Tirona RG; Kim RB; Ho RH
    Mol Cancer Ther; 2015 Apr; 14(4):994-1003. PubMed ID: 25695959
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.
    Lu H; Choudhuri S; Ogura K; Csanaky IL; Lei X; Cheng X; Song PZ; Klaassen CD
    Toxicol Sci; 2008 May; 103(1):35-45. PubMed ID: 18296417
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.
    Zaher H; Meyer zu Schwabedissen HE; Tirona RG; Cox ML; Obert LA; Agrawal N; Palandra J; Stock JL; Kim RB; Ware JA
    Mol Pharmacol; 2008 Aug; 74(2):320-9. PubMed ID: 18413659
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of organic anion transporting polypeptide 1b2 knockout rats generated by CRISPR/Cas9: a novel model for drug transport and hyperbilirubinemia disease.
    Ma X; Shang X; Qin X; Lu J; Liu M; Wang X
    Acta Pharm Sin B; 2020 May; 10(5):850-860. PubMed ID: 32528832
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice.
    Csanaky IL; Lu H; Zhang Y; Ogura K; Choudhuri S; Klaassen CD
    Hepatology; 2011 Jan; 53(1):272-81. PubMed ID: 20949553
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake.
    Niemi M; Pasanen MK; Neuvonen PJ
    Pharmacol Rev; 2011 Mar; 63(1):157-81. PubMed ID: 21245207
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Organic Anion-Transporting Polypeptide 1B1/1B3-Mediated Hepatic Uptake Determines the Pharmacokinetics of Large Lipophilic Acids: In Vitro-In Vivo Evaluation in Cynomolgus Monkey.
    Eng H; Bi YA; West MA; Ryu S; Yamaguchi E; Kosa RE; Tess DA; Griffith DA; Litchfield J; Kalgutkar AS; Varma MVS
    J Pharmacol Exp Ther; 2021 Apr; 377(1):169-180. PubMed ID: 33509903
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gender, but not CYP7A1 or SLCO1B1 polymorphism, affects the fasting plasma concentrations of bile acids in human beings.
    Xiang X; Backman JT; Neuvonen PJ; Niemi M
    Basic Clin Pharmacol Toxicol; 2012 Mar; 110(3):245-52. PubMed ID: 21902813
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice.
    Slijepcevic D; Roscam Abbing RLP; Katafuchi T; Blank A; Donkers JM; van Hoppe S; de Waart DR; Tolenaars D; van der Meer JHM; Wildenberg M; Beuers U; Oude Elferink RPJ; Schinkel AH; van de Graaf SFJ
    Hepatology; 2017 Nov; 66(5):1631-1643. PubMed ID: 28498614
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Organic anion transporter 1B1: an important factor in hepatic thyroid hormone and estrogen transport and metabolism.
    van der Deure WM; Friesema EC; de Jong FJ; de Rijke YB; de Jong FH; Uitterlinden AG; Breteler MM; Peeters RP; Visser TJ
    Endocrinology; 2008 Sep; 149(9):4695-701. PubMed ID: 18499754
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2.
    Meyer Zu Schwabedissen HE; Ware JA; Tirona RG; Kim RB
    Mol Pharm; 2009; 6(6):1790-7. PubMed ID: 19400585
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gender-divergent profile of bile acid homeostasis during aging of mice.
    Fu ZD; Csanaky IL; Klaassen CD
    PLoS One; 2012; 7(3):e32551. PubMed ID: 22403674
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Methotrexate pharmacokinetics in transgenic mice with liver-specific expression of human organic anion-transporting polypeptide 1B1 (SLCO1B1).
    van de Steeg E; van der Kruijssen CM; Wagenaar E; Burggraaff JE; Mesman E; Kenworthy KE; Schinkel AH
    Drug Metab Dispos; 2009 Feb; 37(2):277-81. PubMed ID: 19022939
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overexpression of cholesterol 7α-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis.
    Li T; Matozel M; Boehme S; Kong B; Nilsson LM; Guo G; Ellis E; Chiang JY
    Hepatology; 2011 Mar; 53(3):996-1006. PubMed ID: 21319191
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Influence of non-steroidal anti-inflammatory drugs on organic anion transporting polypeptide (OATP) 1B1- and OATP1B3-mediated drug transport.
    Kindla J; Müller F; Mieth M; Fromm MF; König J
    Drug Metab Dispos; 2011 Jun; 39(6):1047-53. PubMed ID: 21389119
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Editor's Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARα-Dependent Manner.
    Zhang Y; Lickteig AJ; Csanaky IL; Klaassen CD
    Toxicol Sci; 2017 Dec; 160(2):351-360. PubMed ID: 28973556
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel.
    Iusuf D; Hendrikx JJ; van Esch A; van de Steeg E; Wagenaar E; Rosing H; Beijnen JH; Schinkel AH
    Int J Cancer; 2015 Jan; 136(1):225-33. PubMed ID: 24825069
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.
    Zimmerman EI; Hu S; Roberts JL; Gibson AA; Orwick SJ; Li L; Sparreboom A; Baker SD
    Clin Cancer Res; 2013 Mar; 19(6):1458-66. PubMed ID: 23340295
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hepatic OATP1B transporters and nuclear receptors PXR and CAR: interplay, regulation of drug disposition genes, and single nucleotide polymorphisms.
    Meyer zu Schwabedissen HE; Kim RB
    Mol Pharm; 2009; 6(6):1644-61. PubMed ID: 19558188
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.