These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

287 related articles for article (PubMed ID: 21540331)

  • 1. Two distinct conformations of helix 6 observed in antagonist-bound structures of a beta1-adrenergic receptor.
    Moukhametzianov R; Warne T; Edwards PC; Serrano-Vega MJ; Leslie AG; Tate CG; Schertler GF
    Proc Natl Acad Sci U S A; 2011 May; 108(20):8228-32. PubMed ID: 21540331
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure of a beta1-adrenergic G-protein-coupled receptor.
    Warne T; Serrano-Vega MJ; Baker JG; Moukhametzianov R; Edwards PC; Henderson R; Leslie AG; Tate CG; Schertler GF
    Nature; 2008 Jul; 454(7203):486-91. PubMed ID: 18594507
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor.
    Warne T; Moukhametzianov R; Baker JG; Nehmé R; Edwards PC; Leslie AG; Schertler GF; Tate CG
    Nature; 2011 Jan; 469(7329):241-4. PubMed ID: 21228877
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Observation of "ionic lock" formation in molecular dynamics simulations of wild-type beta 1 and beta 2 adrenergic receptors.
    Vanni S; Neri M; Tavernelli I; Rothlisberger U
    Biochemistry; 2009 Jun; 48(22):4789-97. PubMed ID: 19378975
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of two distinct inactive conformations of the beta2-adrenergic receptor reconciles structural and biochemical observations.
    Dror RO; Arlow DH; Borhani DW; Jensen MØ; Piana S; Shaw DE
    Proc Natl Acad Sci U S A; 2009 Mar; 106(12):4689-94. PubMed ID: 19258456
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural insights into conformational stability of wild-type and mutant beta1-adrenergic receptor.
    Balaraman GS; Bhattacharya S; Vaidehi N
    Biophys J; 2010 Jul; 99(2):568-77. PubMed ID: 20643076
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Engineering an ultra-thermostable β(1)-adrenoceptor.
    Miller JL; Tate CG
    J Mol Biol; 2011 Oct; 413(3):628-38. PubMed ID: 21907721
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.
    Bhattacharya S; Hall SE; Vaidehi N
    J Mol Biol; 2008 Oct; 382(2):539-55. PubMed ID: 18638482
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-Based Prediction of G-Protein-Coupled Receptor Ligand Function: A β-Adrenoceptor Case Study.
    Kooistra AJ; Leurs R; de Esch IJ; de Graaf C
    J Chem Inf Model; 2015 May; 55(5):1045-61. PubMed ID: 25848966
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor.
    Isogai S; Deupi X; Opitz C; Heydenreich FM; Tsai CJ; Brueckner F; Schertler GF; Veprintsev DB; Grzesiek S
    Nature; 2016 Feb; 530(7589):237-41. PubMed ID: 26840483
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GPCRs through the keyhole: the role of protein flexibility in ligand binding to β-adrenoceptors.
    Emtage AL; Mistry SN; Fischer PM; Kellam B; Laughton CA
    J Biomol Struct Dyn; 2017 Sep; 35(12):2604-2619. PubMed ID: 27532213
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conformational plasticity of ligand-bound and ternary GPCR complexes studied by
    Frei JN; Broadhurst RW; Bostock MJ; Solt A; Jones AJY; Gabriel F; Tandale A; Shrestha B; Nietlispach D
    Nat Commun; 2020 Feb; 11(1):669. PubMed ID: 32015348
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structure of oligomeric β1-adrenergic G protein-coupled receptors in ligand-free basal state.
    Huang J; Chen S; Zhang JJ; Huang XY
    Nat Struct Mol Biol; 2013 Apr; 20(4):419-25. PubMed ID: 23435379
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The hydrophobic amino acid cluster at the cytoplasmic end of transmembrane helix III modulates the coupling of the β(1)-adrenergic receptor to G(s).
    Hajjhussein H; Gardner LA; Fujii N; Anderson NM; Bahouth SW
    J Recept Signal Transduct Res; 2013 Apr; 33(2):79-88. PubMed ID: 23351074
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transferability of thermostabilizing mutations between beta-adrenergic receptors.
    Serrano-Vega MJ; Tate CG
    Mol Membr Biol; 2009 Dec; 26(8):385-96. PubMed ID: 19883298
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutagenesis within helix 6 of the human beta1-adrenergic receptor identifies Lysine324 as a residue involved in imparting the high-affinity binding state of agonists.
    Zeitoun O; Santos NM; Gardner LA; White SW; Bahouth SW
    Mol Pharmacol; 2006 Sep; 70(3):838-50. PubMed ID: 16760361
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structures of a stabilized β1-adrenoceptor bound to the biased agonists bucindolol and carvedilol.
    Warne T; Edwards PC; Leslie AG; Tate CG
    Structure; 2012 May; 20(5):841-9. PubMed ID: 22579251
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural features of β2 adrenergic receptor: crystal structures and beyond.
    Bang I; Choi HJ
    Mol Cells; 2015; 38(2):105-11. PubMed ID: 25537861
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The formation of a salt bridge between helices 3 and 6 is responsible for the constitutive activity and lack of hormone responsiveness of the naturally occurring L457R mutation of the human lutropin receptor.
    Zhang M; Mizrachi D; Fanelli F; Segaloff DL
    J Biol Chem; 2005 Jul; 280(28):26169-76. PubMed ID: 15908694
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The 2.1 Å resolution structure of cyanopindolol-bound β1-adrenoceptor identifies an intramembrane Na+ ion that stabilises the ligand-free receptor.
    Miller-Gallacher JL; Nehmé R; Warne T; Edwards PC; Schertler GF; Leslie AG; Tate CG
    PLoS One; 2014; 9(3):e92727. PubMed ID: 24663151
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.