BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 21540351)

  • 1. High-content analysis of CCR2 antagonists on human primary monocytes.
    Kredel S; Wolff M; Hobbie S; Bieler M; Gierschik P; Heilker R
    J Biomol Screen; 2011 Aug; 16(7):683-93. PubMed ID: 21540351
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Assessment of chemokine receptor function on monocytes in whole blood: In vitro and ex vivo evaluations of a CCR2 antagonist.
    Wisniewski T; Bayne E; Flanagan J; Shao Q; Wnek R; Matheravidathu S; Fischer P; Forrest MJ; Peterson L; Song X; Yang L; Demartino JA; Struthers M
    J Immunol Methods; 2010 Jan; 352(1-2):101-10. PubMed ID: 19913021
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Recent developments in CCR2 antagonists.
    Xia M; Sui Z
    Expert Opin Ther Pat; 2009 Mar; 19(3):295-303. PubMed ID: 19441905
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MCP-1/CCR2-dependent loop for fibrogenesis in human peripheral CD14-positive monocytes.
    Sakai N; Wada T; Furuichi K; Shimizu K; Kokubo S; Hara A; Yamahana J; Okumura T; Matsushima K; Yokoyama H; Kaneko S
    J Leukoc Biol; 2006 Mar; 79(3):555-63. PubMed ID: 16415174
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo.
    Han KH; Ryu J; Hong KH; Ko J; Pak YK; Kim JB; Park SW; Kim JJ
    Circulation; 2005 Mar; 111(11):1439-47. PubMed ID: 15781755
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacological characterization of INCB3344, a small molecule antagonist of human CCR2.
    Shin N; Baribaud F; Wang K; Yang G; Wynn R; Covington MB; Feldman P; Gallagher KB; Leffet LM; Lo YY; Wang A; Xue CB; Newton RC; Scherle PA
    Biochem Biophys Res Commun; 2009 Sep; 387(2):251-5. PubMed ID: 19576173
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Isolation and structures of novel fungal metabolites as chemokine receptor (CCR2) antagonists.
    Herath KB; Jayasuriya H; Ondeyka JG; Polishook JD; Bills GF; Dombrowski AW; Cabello A; Vicario PP; Zweerink H; Guan Z; Singh SB
    J Antibiot (Tokyo); 2005 Nov; 58(11):686-94. PubMed ID: 16466022
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacological profile of JNJ-27141491 [(S)-3-[3,4-difluorophenyl)-propyl]-5-isoxazol-5-yl-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxyl acid methyl ester], as a noncompetitive and orally active antagonist of the human chemokine receptor CCR2.
    Buntinx M; Hermans B; Goossens J; Moechars D; Gilissen RA; Doyon J; Boeckx S; Coesemans E; Van Lommen G; Van Wauwe JP
    J Pharmacol Exp Ther; 2008 Oct; 327(1):1-9. PubMed ID: 18599682
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective inhibition of expression of the chemokine receptor CCR2 in human monocytes by IFN-gamma.
    Penton-Rol G; Polentarutti N; Luini W; Borsatti A; Mancinelli R; Sica A; Sozzani S; Mantovani A
    J Immunol; 1998 Apr; 160(8):3869-73. PubMed ID: 9558092
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series.
    Moree WJ; Kataoka K; Ramirez-Weinhouse MM; Shiota T; Imai M; Tsutsumi T; Sudo M; Endo N; Muroga Y; Hada T; Fanning D; Saunders J; Kato Y; Myers PL; Tarby CM
    Bioorg Med Chem Lett; 2008 Mar; 18(6):1869-73. PubMed ID: 18313297
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Multiple binding sites for small-molecule antagonists at the CC chemokine receptor 2.
    Zweemer AJ; Nederpelt I; Vrieling H; Hafith S; Doornbos ML; de Vries H; Abt J; Gross R; Stamos D; Saunders J; Smit MJ; Ijzerman AP; Heitman LH
    Mol Pharmacol; 2013 Oct; 84(4):551-61. PubMed ID: 23877010
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cilostazol reduces MCP-1-induced chemotaxis and adhesion of THP-1 monocytes by inhibiting CCR2 gene expression.
    Chuang SY; Yang SH; Pang JH
    Biochem Biophys Res Commun; 2011 Jul; 411(2):402-8. PubMed ID: 21756880
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of bacterial cell wall components (PAMPs) on the expression of monocyte chemoattractant protein-1 (MCP-1), macrophage inflammatory protein-1alpha (MIP-1alpha) and the chemokine receptor CCR2 by purified human blood monocytes.
    Møller AS; Øvstebø R; Westvik AB; Joø GB; Haug KB; Kierulf P
    J Endotoxin Res; 2003; 9(6):349-60. PubMed ID: 14733721
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Acute inflammatory reactions caused by histamine via monocytes/macrophages chronically participate in the initiation and progression of atherosclerosis.
    Kimura S; Wang KY; Tanimoto A; Murata Y; Nakashima Y; Sasaguri Y
    Pathol Int; 2004 Jul; 54(7):465-74. PubMed ID: 15189499
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Blocking mast cell-mediated type I hypersensitivity in experimental allergic conjunctivitis by monocyte chemoattractant protein-1/CCR2.
    Tominaga T; Miyazaki D; Sasaki S; Mihara S; Komatsu N; Yakura K; Inoue Y
    Invest Ophthalmol Vis Sci; 2009 Nov; 50(11):5181-8. PubMed ID: 19553621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological profiling of chemokine receptor-directed compounds using high-content screening.
    Haasen D; Merk S; Seither P; Martyres D; Hobbie S; Heilker R
    J Biomol Screen; 2008 Jan; 13(1):40-53. PubMed ID: 18227225
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cloning and functional characterization of the rabbit C-C chemokine receptor 2.
    Lu D; Yuan XJ; Evans RJ; Pappas AT; Wang H; Su EW; Hamdouchi C; Venkataraman C
    BMC Immunol; 2005 Jul; 6():15. PubMed ID: 16001983
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acute excitotoxic injury induces expression of monocyte chemoattractant protein-1 and its receptor, CCR2, in neonatal rat brain.
    Galasso JM; Miller MJ; Cowell RM; Harrison JK; Warren JS; Silverstein FS
    Exp Neurol; 2000 Oct; 165(2):295-305. PubMed ID: 10993690
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of 3,5-bis(trifluoromethyl)benzyl L-arylglycinamide based potent CCR2 antagonists.
    Yang L; Zhou C; Guo L; Morriello G; Butora G; Pasternak A; Parsons WH; Mills SG; MacCoss M; Vicario PP; Zweerink H; Ayala JM; Goyal S; Hanlon WA; Cascieri MA; Springer MS
    Bioorg Med Chem Lett; 2006 Jul; 16(14):3735-9. PubMed ID: 16698264
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Capped diaminopropionamide-glycine dipeptides are inhibitors of CC chemokine receptor 2 (CCR2).
    Carter PH; Brown GD; Friedrich SR; Cherney RJ; Tebben AJ; Lo YC; Yang G; Jezak H; Solomon KA; Scherle PA; Decicco CP
    Bioorg Med Chem Lett; 2007 Oct; 17(19):5455-61. PubMed ID: 17720492
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.