These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 21542029)

  • 1. Analysis of mutations in the Pig-a gene of spleen T-cells from N-ethyl-N-nitrosourea-treated fisher 344 rats.
    Miura D; Shaddock JG; Mittelstaedt RA; Dobrovolsky VN; Kimoto T; Kasahara Y; Heflich RH
    Environ Mol Mutagen; 2011 Jun; 52(5):419-23. PubMed ID: 21542029
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Development of an in vivo gene mutation assay using the endogenous Pig-A gene: II. Selection of Pig-A mutant rat spleen T-cells with proaerolysin and sequencing Pig-A cDNA from the mutants.
    Miura D; Dobrovolsky VN; Mittelstaedt RA; Kasahara Y; Katsuura Y; Heflich RH
    Environ Mol Mutagen; 2008 Oct; 49(8):622-30. PubMed ID: 18626996
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Accumulation and persistence of Pig-A mutant peripheral red blood cells following treatment of rats with single and split doses of N-ethyl-N-nitrosourea.
    Miura D; Dobrovolsky VN; Kimoto T; Kasahara Y; Heflich RH
    Mutat Res; 2009; 677(1-2):86-92. PubMed ID: 19501187
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Manifestation of Pig-a mutant bone marrow erythroids and peripheral blood erythrocytes in mice treated with N-ethyl-N-nitrosourea: direct sequencing of Pig-a cDNA from bone marrow cells negative for GPI-anchored protein expression.
    Kimoto T; Suzuki K; Kobayashi XM; Dobrovolsky VN; Heflich RH; Miura D; Kasahara Y
    Mutat Res; 2011 Jul; 723(1):36-42. PubMed ID: 21549855
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of an in vivo gene mutation assay using the endogenous Pig-A gene: I. Flow cytometric detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat.
    Miura D; Dobrovolsky VN; Kasahara Y; Katsuura Y; Heflich RH
    Environ Mol Mutagen; 2008 Oct; 49(8):614-21. PubMed ID: 18626999
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Frequency and spectrum of ethylnitrosourea-induced mutation at the hprt and lacI loci in splenic lymphocytes of exposed lacI transgenic mice.
    Walker VE; Gorelick NJ; Andrews JL; Craft TR; deBoer JG; Glickman BW; Skopek TR
    Cancer Res; 1996 Oct; 56(20):4654-61. PubMed ID: 8840980
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular analysis of in vivo mutations induced by N-ethyl-N-nitrosourea in the autosomal Tk and the X-linked Hprt genes of mouse lymphocytes.
    Dobrovolsky VN; Chen T; Heflich RH
    Environ Mol Mutagen; 1999; 34(1):30-8. PubMed ID: 10462721
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant frequency and mutational spectra in the Tk and Hprt genes of N-ethyl-N-nitrosourea-treated mouse lymphoma cellsdagger.
    Chen T; Harrington-Brock K; Moore MM
    Environ Mol Mutagen; 2002; 39(4):296-305. PubMed ID: 12112381
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Confirmation of Pig-a mutation in flow cytometry-identified CD48-deficient T-lymphocytes from F344 rats.
    Revollo J; Pearce MG; Petibone DM; Mittelstaedt RA; Dobrovolsky VN
    Mutagenesis; 2015 May; 30(3):315-24. PubMed ID: 25820172
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CD48-deficient T-lymphocytes from DMBA-treated rats have de novo mutations in the endogenous Pig-a gene.
    Dobrovolsky VN; Revollo J; Pearce MG; Pacheco-Martinez MM; Lin H
    Environ Mol Mutagen; 2015 Oct; 56(8):674-83. PubMed ID: 26033714
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Marked differences in the role of O6-alkylguanine in hprt mutagenesis in T-lymphocytes of rats exposed in vivo to ethylmethanesulfonate, N-(2-hydroxyethyl)-N-nitrosourea, or N-ethyl-N-nitrosourea.
    Jansen JG; Vrieling H; van Teijlingen CM; Mohn GR; Tates AD; van Zeeland AA
    Cancer Res; 1995 May; 55(9):1875-82. PubMed ID: 7728755
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The in vivo Pig-a gene mutation assay, a potential tool for regulatory safety assessment.
    Dobrovolsky VN; Miura D; Heflich RH; Dertinger SD
    Environ Mol Mutagen; 2010; 51(8-9):825-35. PubMed ID: 20857433
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 1,3-butadiene: cancer, mutations, and adducts. Part II: Roles of two metabolites of 1,3-butadiene in mediating its in vivo genotoxicity.
    Recio L; Saranko CJ; Steen AM
    Res Rep Health Eff Inst; 2000 Mar; (92):49-87; discussion 141-9. PubMed ID: 10925839
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of Macaca mulatta as a model for genotoxicity studies.
    Dobrovolsky VN; Shaddock JG; Mittelstaedt RA; Manjanatha MG; Miura D; Uchikawa M; Mattison DR; Morris SM
    Mutat Res; 2009 Feb; 673(1):21-8. PubMed ID: 19073277
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analysis of mutation in the rat Pig-a assay: I) studies with bone marrow erythroid cells.
    Revollo JR; Pearce MG; Dad A; Petibone DM; Robison TW; Roberts D; Dobrovolsky VN
    Environ Mol Mutagen; 2018 Oct; 59(8):722-732. PubMed ID: 30091272
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular analysis of hprt gene mutations in skin fibroblasts of rats exposed in vivo to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea.
    Jansen JG; Mohn GR; Vrieling H; van Teijlingen CM; Lohman PH; van Zeeland AA
    Cancer Res; 1994 May; 54(9):2478-85. PubMed ID: 8162597
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Spontaneous and ethylnitrosourea-induced mutation fixation and molecular spectra at the lacI transgene in the Big Blue rat-2 embryo cell line.
    Zimmer DM; Zhang XB; Harbach PR; Mayo JK; Aaron CS
    Environ Mol Mutagen; 1996; 28(4):325-33. PubMed ID: 8991060
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genotoxicity of 1,3-butadiene and its epoxy intermediates.
    Walker VE; Walker DM; Meng Q; McDonald JD; Scott BR; Seilkop SK; Claffey DJ; Upton PB; Powley MW; Swenberg JA; Henderson RF;
    Res Rep Health Eff Inst; 2009 Aug; (144):3-79. PubMed ID: 20017413
    [TBL] [Abstract][Full Text] [Related]  

  • 19. International Pig-a gene mutation assay trial: evaluation of transferability across 14 laboratories.
    Dertinger SD; Phonethepswath S; Weller P; Nicolette J; Murray J; Sonders P; Vohr HW; Shi J; Krsmanovic L; Gleason C; Custer L; Henwood A; Sweder K; Stankowski LF; Roberts DJ; Giddings A; Kenny J; Lynch AM; Defrain C; Nesslany F; van der Leede BJ; Van Doninck T; Schuermans A; Tanaka K; Hiwata Y; Tajima O; Wilde E; Elhajouji A; Gunther WC; Thiffeault CJ; Shutsky TJ; Fiedler RD; Kimoto T; Bhalli JA; Heflich RH; MacGregor JT
    Environ Mol Mutagen; 2011 Dec; 52(9):690-8. PubMed ID: 21910140
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of in vivo genotoxicity induced by N-ethyl-N-nitrosourea, benzo[a]pyrene, and 4-nitroquinoline-1-oxide in the Pig-a and gpt assays.
    Horibata K; Ukai A; Kimoto T; Suzuki T; Kamoshita N; Masumura K; Nohmi T; Honma M
    Environ Mol Mutagen; 2013 Dec; 54(9):747-54. PubMed ID: 24105957
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.