BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 21543316)

  • 1. NMR solution structure of human vaccinia-related kinase 1 (VRK1) reveals the C-terminal tail essential for its structural stability and autocatalytic activity.
    Shin J; Chakraborty G; Bharatham N; Kang C; Tochio N; Koshiba S; Kigawa T; Kim W; Kim KT; Yoon HS
    J Biol Chem; 2011 Jun; 286(25):22131-8. PubMed ID: 21543316
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of human vaccinia-related kinase 1 in complex with AMP-PNP, a non-hydrolyzable ATP analog.
    Ngow YS; Rajan S; Ye H; Yoon HS
    Protein Sci; 2019 Mar; 28(3):524-532. PubMed ID: 30461091
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Backbone ¹H, ¹³C and ¹⁵N resonance assignments of human vaccinia-related kinase 1 (VRK1).
    Shin J; Chakraborty G; Yoon HS
    Biomol NMR Assign; 2014 Apr; 8(1):29-31. PubMed ID: 23212441
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activities.
    Sanz-García M; López-Sánchez I; Lazo PA
    Mol Cell Proteomics; 2008 Nov; 7(11):2199-214. PubMed ID: 18617507
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of three paralogous members of the Mammalian vaccinia related kinase family.
    Nichols RJ; Traktman P
    J Biol Chem; 2004 Feb; 279(9):7934-46. PubMed ID: 14645249
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.
    Lopez-Borges S; Lazo PA
    Oncogene; 2000 Jul; 19(32):3656-64. PubMed ID: 10951572
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential inhibitor sensitivity between human kinases VRK1 and VRK2.
    Vázquez-Cedeira M; Barcia-Sanjurjo I; Sanz-García M; Barcia R; Lazo PA
    PLoS One; 2011; 6(8):e23235. PubMed ID: 21829721
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparative Interactomes of VRK1 and VRK3 with Their Distinct Roles in the Cell Cycle of Liver Cancer.
    Lee N; Kim DK; Han SH; Ryu HG; Park SJ; Kim KT; Choi KY
    Mol Cells; 2017 Sep; 40(9):621-631. PubMed ID: 28927264
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of bivalent cations in structural stabilities of new drug targets--vaccinia-related kinases (VRK) from molecular dynamics simulations.
    Fu T; Ren H; Zhang J; Ren P; Enyedy I; Li G
    Curr Pharm Des; 2013; 19(12):2269-81. PubMed ID: 23082977
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations.
    Couñago RM; Allerston CK; Savitsky P; Azevedo H; Godoi PH; Wells CI; Mascarello A; de Souza Gama FH; Massirer KB; Zuercher WJ; Guimarães CRW; Gileadi O
    Sci Rep; 2017 Aug; 7(1):7501. PubMed ID: 28790404
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dysregulation of Cellular VRK1, BAF, and Innate Immune Signaling by the Vaccinia Virus B12 Pseudokinase.
    Linville AC; Rico AB; Teague H; Binsted LE; Smith GL; Albarnaz JD; Wiebe MS
    J Virol; 2022 Jun; 96(11):e0039822. PubMed ID: 35543552
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Vaccinia Virus B12 Pseudokinase Represses Viral Replication via Interaction with the Cellular Kinase VRK1 and Activation of the Antiviral Effector BAF.
    Rico AB; Linville AC; Olson AT; Wang Z; Wiebe MS
    J Virol; 2021 Jan; 95(3):. PubMed ID: 33177193
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ursolic acid exerts anti-cancer activity by suppressing vaccinia-related kinase 1-mediated damage repair in lung cancer cells.
    Kim SH; Ryu HG; Lee J; Shin J; Harikishore A; Jung HY; Kim YS; Lyu HN; Oh E; Baek NI; Choi KY; Yoon HS; Kim KT
    Sci Rep; 2015 Sep; 5():14570. PubMed ID: 26412148
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Substrate profiling of human vaccinia-related kinases identifies coilin, a Cajal body nuclear protein, as a phosphorylation target with neurological implications.
    Sanz-García M; Vázquez-Cedeira M; Kellerman E; Renbaum P; Levy-Lahad E; Lazo PA
    J Proteomics; 2011 Dec; 75(2):548-60. PubMed ID: 21920476
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure and functional characterization of the atypical human kinase haspin.
    Eswaran J; Patnaik D; Filippakopoulos P; Wang F; Stein RL; Murray JW; Higgins JM; Knapp S
    Proc Natl Acad Sci U S A; 2009 Dec; 106(48):20198-203. PubMed ID: 19918057
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphorylation of vaccinia-related kinase 1 at threonine 386 transduces glucose stress signal in human liver cells.
    Yokobori K; Miyauchi Y; Williams JG; Negishi M
    Biosci Rep; 2020 Apr; 40(4):. PubMed ID: 32266931
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53.
    Valbuena A; Blanco S; Vega FM; Lazo PA
    PLoS One; 2008 Jul; 3(7):e2649. PubMed ID: 18612383
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Luteolin suppresses cancer cell proliferation by targeting vaccinia-related kinase 1.
    Kim YS; Kim SH; Shin J; Harikishore A; Lim JK; Jung Y; Lyu HN; Baek NI; Choi KY; Yoon HS; Kim KT
    PLoS One; 2014; 9(10):e109655. PubMed ID: 25310002
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner.
    Bailey FP; Byrne DP; Oruganty K; Eyers CE; Novotny CJ; Shokat KM; Kannan N; Eyers PA
    Biochem J; 2015 Apr; 467(1):47-62. PubMed ID: 25583260
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p53 Stabilization and accumulation induced by human vaccinia-related kinase 1.
    Vega FM; Sevilla A; Lazo PA
    Mol Cell Biol; 2004 Dec; 24(23):10366-80. PubMed ID: 15542844
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.