177 related articles for article (PubMed ID: 21545053)
1. Innovative fluorine-addition process could enable faster drug design and manufacture.
Future Med Chem; 2009 Sep; 1(6):1028. PubMed ID: 21545053
[No Abstract] [Full Text] [Related]
2. Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001-2011).
Wang J; Sánchez-Roselló M; Aceña JL; del Pozo C; Sorochinsky AE; Fustero S; Soloshonok VA; Liu H
Chem Rev; 2014 Feb; 114(4):2432-506. PubMed ID: 24299176
[No Abstract] [Full Text] [Related]
3. Route design, the foundation of successful chemical development.
Cornwall P; Diorazio LJ; Monks N
Bioorg Med Chem; 2018 Aug; 26(14):4336-4347. PubMed ID: 29925485
[TBL] [Abstract][Full Text] [Related]
4. Metabolic and Pharmaceutical Aspects of Fluorinated Compounds.
Johnson BM; Shu YZ; Zhuo X; Meanwell NA
J Med Chem; 2020 Jun; 63(12):6315-6386. PubMed ID: 32182061
[TBL] [Abstract][Full Text] [Related]
5. The role of fluorine in medicinal chemistry.
Shah P; Westwell AD
J Enzyme Inhib Med Chem; 2007 Oct; 22(5):527-40. PubMed ID: 18035820
[TBL] [Abstract][Full Text] [Related]
6. Data-mining for sulfur and fluorine: an evaluation of pharmaceuticals to reveal opportunities for drug design and discovery.
Ilardi EA; Vitaku E; Njardarson JT
J Med Chem; 2014 Apr; 57(7):2832-42. PubMed ID: 24102067
[TBL] [Abstract][Full Text] [Related]
7. Selective synthesis of poly-substituted fluorine-containing pyridines and dihydropyrimidines via cascade C-F bond cleavage protocol.
Chen Z; Zhu J; Xie H; Li S; Wu Y; Gong Y
Org Biomol Chem; 2011 Aug; 9(16):5682-91. PubMed ID: 21717032
[TBL] [Abstract][Full Text] [Related]
8. Analysis of the reactions used for the preparation of drug candidate molecules.
Carey JS; Laffan D; Thomson C; Williams MT
Org Biomol Chem; 2006 Jun; 4(12):2337-47. PubMed ID: 16763676
[TBL] [Abstract][Full Text] [Related]
9. Chirality and its importance in drug development: a synthetic chemist's perspective.
Roberts SM
Biochem Soc Trans; 1991 Apr; 19(2):446-53. PubMed ID: 1889627
[No Abstract] [Full Text] [Related]
10. Synthetic approaches to the 2007 new drugs.
Liu KK; Sakya SM; O'Donnell CJ; Li J
Mini Rev Med Chem; 2008 Dec; 8(14):1526-48. PubMed ID: 19075810
[TBL] [Abstract][Full Text] [Related]
11. Natural products as leads to potential drugs: an old process or the new hope for drug discovery?
Newman DJ
J Med Chem; 2008 May; 51(9):2589-99. PubMed ID: 18393402
[No Abstract] [Full Text] [Related]
12. High-throughput and parallel screening methods in asymmetric hydrogenation.
Jäkel C; Paciello R
Chem Rev; 2006 Jul; 106(7):2912-42. PubMed ID: 16836304
[No Abstract] [Full Text] [Related]
13. Starting from scratch.
Chapman T
Nature; 2004 Jul; 430(6995):113. PubMed ID: 15229610
[No Abstract] [Full Text] [Related]
14. Molecular Complexity as a Driver for Chemical Process Innovation in the Pharmaceutical Industry.
Caille S; Cui S; Faul MM; Mennen SM; Tedrow JS; Walker SD
J Org Chem; 2019 Apr; 84(8):4583-4603. PubMed ID: 30916557
[TBL] [Abstract][Full Text] [Related]
15. Synthetic approaches to the 2010 new drugs.
Liu KK; Sakya SM; O'Donnell CJ; Flick AC; Ding HX
Bioorg Med Chem; 2012 Feb; 20(3):1155-74. PubMed ID: 22261026
[TBL] [Abstract][Full Text] [Related]
16. Chemical library synthesis using convergent approaches.
Beeler AB; Schaus SE; Porco JA
Curr Opin Chem Biol; 2005 Jun; 9(3):277-84. PubMed ID: 15939329
[TBL] [Abstract][Full Text] [Related]
17. Modern Approaches for Asymmetric Construction of Carbon-Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs.
Zhu Y; Han J; Wang J; Shibata N; Sodeoka M; Soloshonok VA; Coelho JAS; Toste FD
Chem Rev; 2018 Apr; 118(7):3887-3964. PubMed ID: 29608052
[TBL] [Abstract][Full Text] [Related]
18. Fluorine in medicinal chemistry.
Böhm HJ; Banner D; Bendels S; Kansy M; Kuhn B; Müller K; Obst-Sander U; Stahl M
Chembiochem; 2004 May; 5(5):637-43. PubMed ID: 15122635
[TBL] [Abstract][Full Text] [Related]
19. On the art of compiling and using 'drug-like' chemical fragment spaces.
Degen J; Wegscheid-Gerlach C; Zaliani A; Rarey M
ChemMedChem; 2008 Oct; 3(10):1503-7. PubMed ID: 18792903
[No Abstract] [Full Text] [Related]
20. Preface: Additive manufacturing in pharmaceutical product design.
Rantanen J; Fatouros DG
Adv Drug Deliv Rev; 2021 Nov; 178():113991. PubMed ID: 34582829
[No Abstract] [Full Text] [Related]
[Next] [New Search]
