177 related articles for article (PubMed ID: 21545152)
1. Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1.
Duncan KE; Dempsey BR; Killip LE; Adams J; Bailey ML; Lajoie GA; Litchfield DW; Brandl CJ; Shaw GS; Shilton BH
J Med Chem; 2011 Jun; 54(11):3854-65. PubMed ID: 21545152
[TBL] [Abstract][Full Text] [Related]
2. Membrane permeable cyclic peptidyl inhibitors against human Peptidylprolyl Isomerase Pin1.
Liu T; Liu Y; Kao HY; Pei D
J Med Chem; 2010 Mar; 53(6):2494-501. PubMed ID: 20180533
[TBL] [Abstract][Full Text] [Related]
3. Structural basis for high-affinity peptide inhibition of human Pin1.
Zhang Y; Daum S; Wildemann D; Zhou XZ; Verdecia MA; Bowman ME; Lücke C; Hunter T; Lu KP; Fischer G; Noel JP
ACS Chem Biol; 2007 May; 2(5):320-8. PubMed ID: 17518432
[TBL] [Abstract][Full Text] [Related]
4. Structure-based design of novel human Pin1 inhibitors (II).
Dong L; Marakovits J; Hou X; Guo C; Greasley S; Dagostino E; Ferre R; Johnson MC; Kraynov E; Thomson J; Pathak V; Murray BW
Bioorg Med Chem Lett; 2010 Apr; 20(7):2210-4. PubMed ID: 20207139
[TBL] [Abstract][Full Text] [Related]
5. Stereospecific gating of functional motions in Pin1.
Namanja AT; Wang XJ; Xu B; Mercedes-Camacho AY; Wilson KA; Etzkorn FA; Peng JW
Proc Natl Acad Sci U S A; 2011 Jul; 108(30):12289-94. PubMed ID: 21746900
[TBL] [Abstract][Full Text] [Related]
6. Structure-based design of novel human Pin1 inhibitors (III): optimizing affinity beyond the phosphate recognition pocket.
Guo C; Hou X; Dong L; Marakovits J; Greasley S; Dagostino E; Ferre R; Johnson MC; Humphries PS; Li H; Paderes GD; Piraino J; Kraynov E; Murray BW
Bioorg Med Chem Lett; 2014 Sep; 24(17):4187-91. PubMed ID: 25091930
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of the novel elemonic acid derivatives as Pin1 inhibitors.
Li X; Li L; Zhou Q; Zhang N; Zhang S; Zhao R; Liu D; Jing Y; Zhao L
Bioorg Med Chem Lett; 2014 Dec; 24(24):5612-5615. PubMed ID: 25466185
[TBL] [Abstract][Full Text] [Related]
8. Conformation-directed catalysis and coupled enzyme-substrate dynamics in Pin1 phosphorylation-dependent cis-trans isomerase.
Velazquez HA; Hamelberg D
J Phys Chem B; 2013 Oct; 117(39):11509-17. PubMed ID: 23980573
[TBL] [Abstract][Full Text] [Related]
9. Structure-based design of novel human Pin1 inhibitors (I).
Guo C; Hou X; Dong L; Dagostino E; Greasley S; Ferre R; Marakovits J; Johnson MC; Matthews D; Mroczkowski B; Parge H; Vanarsdale T; Popoff I; Piraino J; Margosiak S; Thomson J; Los G; Murray BW
Bioorg Med Chem Lett; 2009 Oct; 19(19):5613-6. PubMed ID: 19729306
[TBL] [Abstract][Full Text] [Related]
10. [Recent advances in the study of pin1 and its inhibitors].
Zhang CJ; Zhang ZH; Xu BL; Wang YL
Yao Xue Xue Bao; 2008 Jan; 43(1):9-17. PubMed ID: 18357725
[TBL] [Abstract][Full Text] [Related]
11. Substrate-based design of reversible Pin1 inhibitors.
Zhang Y; Füssel S; Reimer U; Schutkowski M; Fischer G
Biochemistry; 2002 Oct; 41(39):11868-77. PubMed ID: 12269831
[TBL] [Abstract][Full Text] [Related]
12. On the benefit of bivalency in peptide ligand/pin1 interactions.
Daum S; Lücke C; Wildemann D; Schiene-Fischer C
J Mol Biol; 2007 Nov; 374(1):147-61. PubMed ID: 17931657
[TBL] [Abstract][Full Text] [Related]
13. A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state.
Xu GG; Zhang Y; Mercedes-Camacho AY; Etzkorn FA
Biochemistry; 2011 Nov; 50(44):9545-50. PubMed ID: 21980916
[TBL] [Abstract][Full Text] [Related]
14. Regulation of Pin1 peptidyl-prolyl cis/trans isomerase activity by its WW binding module on a multi-phosphorylated peptide of Tau protein.
Smet C; Wieruszeski JM; Buée L; Landrieu I; Lippens G
FEBS Lett; 2005 Aug; 579(19):4159-64. PubMed ID: 16024016
[TBL] [Abstract][Full Text] [Related]
15. Peptide binding induces large scale changes in inter-domain mobility in human Pin1.
Jacobs DM; Saxena K; Vogtherr M; Bernado P; Pons M; Fiebig KM
J Biol Chem; 2003 Jul; 278(28):26174-82. PubMed ID: 12686540
[TBL] [Abstract][Full Text] [Related]
16. The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif.
Xu N; Tochio N; Wang J; Tamari Y; Uewaki J; Utsunomiya-Tate N; Igarashi K; Shiraki T; Kobayashi N; Tate S
Biochemistry; 2014 Sep; 53(34):5568-78. PubMed ID: 25100325
[TBL] [Abstract][Full Text] [Related]
17. Modulating the Affinities of Phosphopeptides for the Human Pin1 WW Domain Using 4-Substituted Proline Derivatives.
Huang KY; Horng JC
Biochemistry; 2015 Oct; 54(40):6186-94. PubMed ID: 26406962
[TBL] [Abstract][Full Text] [Related]
18. Thermodynamics of phosphopeptide binding to the human peptidyl prolyl cis/trans isomerase Pin1.
Daum S; Fanghänel J; Wildemann D; Schiene-Fischer C
Biochemistry; 2006 Oct; 45(39):12125-35. PubMed ID: 17002312
[TBL] [Abstract][Full Text] [Related]
19. Pin1 inhibitors: Pitfalls, progress and cellular pharmacology.
Moore JD; Potter A
Bioorg Med Chem Lett; 2013 Aug; 23(15):4283-91. PubMed ID: 23796453
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of novel quinazoline-derived human Pin1 inhibitors.
Zhu L; Jin J; Liu C; Zhang C; Sun Y; Guo Y; Fu D; Chen X; Xu B
Bioorg Med Chem; 2011 May; 19(9):2797-807. PubMed ID: 21504850
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
