BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

412 related articles for article (PubMed ID: 21549128)

  • 1. ALS-causing SOD1 mutations promote production of copper-deficient misfolded species.
    Ip P; Mulligan VK; Chakrabartty A
    J Mol Biol; 2011 Jun; 409(5):839-52. PubMed ID: 21549128
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Denaturational stress induces formation of zinc-deficient monomers of Cu,Zn superoxide dismutase: implications for pathogenesis in amyotrophic lateral sclerosis.
    Mulligan VK; Kerman A; Ho S; Chakrabartty A
    J Mol Biol; 2008 Nov; 383(2):424-36. PubMed ID: 18761352
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Unveiling the unfolding pathway of FALS associated G37R SOD1 mutant: a computational study.
    Milardi D; Pappalardo M; Grasso DM; La Rosa C
    Mol Biosyst; 2010 Jun; 6(6):1032-9. PubMed ID: 20485746
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS.
    Rakhit R; Robertson J; Vande Velde C; Horne P; Ruth DM; Griffin J; Cleveland DW; Cashman NR; Chakrabartty A
    Nat Med; 2007 Jun; 13(6):754-9. PubMed ID: 17486090
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A copper-deficient form of mutant Cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis.
    Tokuda E; Nomura T; Ohara S; Watanabe S; Yamanaka K; Morisaki Y; Misawa H; Furukawa Y
    Biochim Biophys Acta Mol Basis Dis; 2018 Jun; 1864(6 Pt A):2119-2130. PubMed ID: 29551730
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural instability and Cu-dependent pro-oxidant activity acquired by the apo form of mutant SOD1 associated with amyotrophic lateral sclerosis.
    Kitamura F; Fujimaki N; Okita W; Hiramatsu H; Takeuchi H
    Biochemistry; 2011 May; 50(20):4242-50. PubMed ID: 21506602
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanical probes of SOD1 predict systematic trends in metal and dimer affinity of ALS-associated mutants.
    Das A; Plotkin SS
    J Mol Biol; 2013 Mar; 425(5):850-74. PubMed ID: 23291526
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis.
    Watanabe S; Nagano S; Duce J; Kiaei M; Li QX; Tucker SM; Tiwari A; Brown RH; Beal MF; Hayward LJ; Culotta VC; Yoshihara S; Sakoda S; Bush AI
    Free Radic Biol Med; 2007 May; 42(10):1534-42. PubMed ID: 17448900
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metal-deficient SOD1 in amyotrophic lateral sclerosis.
    Hilton JB; White AR; Crouch PJ
    J Mol Med (Berl); 2015 May; 93(5):481-7. PubMed ID: 25754173
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Unfolding and folding kinetics of amyotrophic lateral sclerosis-associated mutant Cu,Zn superoxide dismutases.
    Rumfeldt JA; Lepock JR; Meiering EM
    J Mol Biol; 2009 Jan; 385(1):278-98. PubMed ID: 18951903
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The metal cofactor zinc and interacting membranes modulate SOD1 conformation-aggregation landscape in an in vitro ALS model.
    Sannigrahi A; Chowdhury S; Das B; Banerjee A; Halder A; Kumar A; Saleem M; Naganathan AN; Karmakar S; Chattopadhyay K
    Elife; 2021 Apr; 10():. PubMed ID: 33825682
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanism and thermodynamics of guanidinium chloride-induced denaturation of ALS-associated mutant Cu,Zn superoxide dismutases.
    Rumfeldt JA; Stathopulos PB; Chakrabarrty A; Lepock JR; Meiering EM
    J Mol Biol; 2006 Jan; 355(1):106-23. PubMed ID: 16307756
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Early steps in oxidation-induced SOD1 misfolding: implications for non-amyloid protein aggregation in familial ALS.
    Mulligan VK; Kerman A; Laister RC; Sharda PR; Arslan PE; Chakrabartty A
    J Mol Biol; 2012 Aug; 421(4-5):631-52. PubMed ID: 22542526
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutant SOD1 instability: implications for toxicity in amyotrophic lateral sclerosis.
    Tiwari A; Hayward LJ
    Neurodegener Dis; 2005; 2(3-4):115-27. PubMed ID: 16909016
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular dynamics using atomic-resolution structure reveal structural fluctuations that may lead to polymerization of human Cu-Zn superoxide dismutase.
    Strange RW; Yong CW; Smith W; Hasnain SS
    Proc Natl Acad Sci U S A; 2007 Jun; 104(24):10040-4. PubMed ID: 17548825
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Wild-type Cu/Zn-superoxide dismutase is misfolded in cerebrospinal fluid of sporadic amyotrophic lateral sclerosis.
    Tokuda E; Takei YI; Ohara S; Fujiwara N; Hozumi I; Furukawa Y
    Mol Neurodegener; 2019 Nov; 14(1):42. PubMed ID: 31744522
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Many roads lead to Rome? Multiple modes of Cu,Zn superoxide dismutase destabilization, misfolding and aggregation in amyotrophic lateral sclerosis.
    Broom HR; Rumfeldt JA; Meiering EM
    Essays Biochem; 2014; 56():149-65. PubMed ID: 25131593
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Common dynamical signatures of familial amyotrophic lateral sclerosis-associated structurally diverse Cu, Zn superoxide dismutase mutants.
    Khare SD; Dokholyan NV
    Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3147-52. PubMed ID: 16488975
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural changes to monomeric CuZn superoxide dismutase caused by the familial amyotrophic lateral sclerosis-associated mutation A4V.
    Schmidlin T; Kennedy BK; Daggett V
    Biophys J; 2009 Sep; 97(6):1709-18. PubMed ID: 19751676
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aberrantly increased hydrophobicity shared by mutants of Cu,Zn-superoxide dismutase in familial amyotrophic lateral sclerosis.
    Tiwari A; Xu Z; Hayward LJ
    J Biol Chem; 2005 Aug; 280(33):29771-9. PubMed ID: 15958382
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.